Results 91 to 100 of about 459,449 (308)

Efficient top-k string similarity query algorithms

open access: yesTongxin xuebao, 2014
Computing top-k similar strings based on edit distance,i.e.,given a query string σ and string set S,finding k similar strings to σ based on edit distance from S.Firstly,two adaptive filter strategies based on length-skip index are proposed,such that to ...
Zi-yang CHEN   +3 more
doaj   +2 more sources

Efficient Implementation of Nested-Loop Multimedia Algorithms

open access: yesEURASIP Journal on Advances in Signal Processing, 2001
A novel dependence graph representation called the multiple-order dependence graph for nested-loop formulated multimedia signal processing algorithms is proposed. It allows a concise representation of an entire family of dependence graphs. This powerful
Kittitornkun Surin, Hu YuHen
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Faster Space-Efficient Algorithms for Subset Sum, k-Sum and Related Problems

open access: yes, 2016
We present space efficient Monte Carlo algorithms that solve Subset Sum and Knapsack instances with $n$ items using $O^*(2^{0.86n})$ time and polynomial space, where the $O^*(\cdot)$ notation suppresses factors polynomial in the input size.
Vyas, Nikhil   +5 more
core   +1 more source

Efficient quantum algorithms for set operations

open access: yesScientific Reports
Analyzing the relations between Boolean functions has many applications in many fields, such as database systems, cryptography, and collision problems. This paper proposes four quantum algorithms that use amplitude amplification techniques to perform set
Rehab Elgendy   +3 more
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Efficient evolutionary algorithms for optimal control

open access: yes, 2002
If optimal control problems are solved by means of gradient based local search methods, convergence to local solutions is likely. Recently, there has been an increasing interest in the use of global optimisation algorithms to solve optimal control ...
López Cruz, I.L.
core  

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Improvement of Nemhauser-Trotter Theorem and its applications in parametrized complexity

open access: yes, 2004
Let A and B be two sets of n resp. m disjoint unit disks in the plane, with m n. We consider the problem of finding a translation or rigid motion of A that maximizes the total area of overlap with B.
Cabello Justo, Sergio   +46 more
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

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