Results 111 to 120 of about 459,449 (308)

Efficient Algorithms to Globally Balance a Binary Search Tree

open access: yes, 1984
A binary search tree can be globally balanced by readjustment of pointers or with a sorting process in O(n) time, n being the total number of nodes.
H. Chang, S. Iyengar
core  

Robust machine-learned algorithms for efficient grid operation

open access: yesEnvironmental Data Science
Increasing penetration of variable and intermittent renewable energy resources on the energy grid poses a challenge for reliable and efficient grid operation, necessitating the development of algorithms that are robust to this uncertainty.
Nicolas Christianson   +6 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

EEGRA: Energy Efficient Geographic Routing Algorithms for Wireless Sensor Network [PDF]

open access: yes, 2012
Energy efficiency is critical in wireless sensor networks (WSN) for system reliability and deployment cost. The power consumption of the communication in multi-hop WSN is primarily decided by three factors: routing distance, signal interference, and ...
Chen, Tseng-yi; Wei, Hsin-wen; Lee, Che-rung; Hsu, Tsan-sheng; Shih, Wei-kuan
core  

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Efficient algorithms for the discovery of gapped factors

open access: yesAlgorithms for Molecular Biology, 2011
Background The discovery of surprisingly frequent patterns is of paramount interest in bioinformatics and computational biology. Among the patterns considered, those consisting of pairs of solid words that co-occur within a prescribed maximum distance ...
Pizzi Cinzia   +2 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

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