Results 31 to 40 of about 53,168 (261)

Preliminary planning efficiency evaluation for school buildings considering the tradeoffs of MOOP and planning preferences

open access: yesJournal of Civil Engineering and Management, 2014
Seismic resistance and cost effectiveness are often two important building planning objectives for architects. However, these objectives nearly always share a negative correlation with each other, which can cause planning delays and confusion.
Min-Yuan Cheng, Ching-Shan Chen
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Constructing an optimal investment portfolio for the Bank of Lithuania

open access: yesEkonomika, 2016
The main goal of this article is to illustrate the strategy, devised to improve the effectiveness of utilizing the financial assets, or in this case, the official international reserves, belonging to the Bank of Lithuania.
Birutė Galinienė   +1 more
doaj   +1 more source

Modely analýzy obalu dat s fixním součtem výstupů

open access: yesTrendy v podnikání, 2022
Traditional data envelopment analysis (DEA) models do not consider any relations with respect to the sum of values of outputs. In many real applications, the sum of outputs is predetermined and cannot be changed.
Josef Jablonský
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

A Meta-heuristic Algorithm for Portfolio Selection Problem under Cardinality and Bounding Constraints [PDF]

open access: yesپژوهشهای اقتصادی, 2008
The focus of this paper is on standard Markowitz mean–variance model and its traditional approach to solve portfolio selection problem (Quadratic Planning).
mohammad taghi Taqavi Fard   +2 more
doaj  

The impact of cryptocurrency on the efficient frontier of emerging markets

open access: yesCroatian Review of Economic, Business and Social Statistics, 2019
Cryptocurrencies are a sweltering topic in modern times of investment strategies. Since the cryptocurrency market is classified as an emerging market, in this paper a portfolio of emerging markets is compiled from the indices of four European Union (EU ...
Ćosić Karlo, Časni Anita Čeh
doaj   +1 more source

Graph Search-Based Exploration Method Using a Frontier-Graph Structure for Mobile Robots

open access: yesSensors, 2020
This paper describes a graph search-based exploration method. Segmented frontier nodes and their relative transformations constitute a frontier-graph structure.
Hyejeong Ryu
doaj   +1 more source

A new methodology for deriving the efficient frontier of stocks portfolios: An advanced risk-return model [PDF]

open access: yesJournal of Artificial Intelligence and Data Mining, 2014
In this paper after a general literature review on the concept of Efficient Frontier (EF), an important inadequacy of the Variance based models for deriving EFs and the high necessity for applying another risk measure is exemplified.
Sh. Mehrjoo, M. Jasemi, A. Mahmoudi
doaj   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

open access: yesMolecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant   +7 more
wiley   +1 more source

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