Results 161 to 170 of about 3,747,631 (288)

Efficient Solution-Phase Synthesis of Sequence-Defined Oligourethanes with Precise Chirality Control. [PDF]

Macromol Rapid Commun
Sharma A, Samanta T, Cybińska J.
europepmc   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Leveraging ChatGPT for Report Error Audit: An Accuracy-Driven and Cost-Efficient Solution for Ophthalmic Imaging Reports. [PDF]

Ophthalmol Ther
Xu Y, Kang D, Shi D, Tham YC, Grzybowski A, Jin K.   +5 more
europepmc   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Acceptor-Bridged Engineering Enables Highly Efficient Solution-Processed Pure-Green MR-TADF OLEDs With External Quantum Efficiency of 29% and Small Roll-Off. [PDF]

Adv Sci (Weinh)
Zhuang X, Zhang Q, Wei J, Li Z, Liang B, Wang C, Bi H, Wang Y, Lu G.   +8 more
europepmc   +1 more source

Copper Bromide as an Efficient Solution-Processable Hole Transport Layer for Organic Solar Cells: Effect of Solvents. [PDF]

ACS Omega, 2019
Bhargav R, Chaudhary N, Rathi S, Shahjad, Bhardwaj D, Gupta S, Patra A.   +6 more
europepmc   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Efficient Solution-Phase Dipeptide Synthesis Using Titanium Tetrachloride and Microwave Heating. [PDF]

Int J Mol Sci
Cavallaro PA, De Santo M, Marinaro R, Belsito EL, Liguori A, Leggio A.   +5 more
europepmc   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

An innovative bio-inspired Aquila technique for efficient solution of combined power and heat economic dispatch problem. [PDF]

Sci Rep
Hakmi SH, Moustafa G, Alnami H, Mansour HSE, Ginidi A.   +4 more
europepmc   +1 more source