Results 101 to 110 of about 272,567 (316)

A Rare Allele of ST5 From Wild Rice Enhances Salt Tolerance in Rice

Advanced Science, EarlyView.
A novel salt‐tolerance gene ST5W, characterized by a unique 36‐bp promoter insertion, is found exclusively in a small subset of Oryza rufipogon and is absent in cultivated rice. Field trials confirm ST5W significantly enhances rice yield across diverse genetic backgrounds under saline conditions.
Meng Xing, Jingfen Huang, Qiaoling Yuan, Ziyi Yang, Yanyan Wang, Mingchao Zhao, Yamin Nie, Rui Xu, Hongge Qian, Wenxi Chen, Qiaoling Zhang, Qi Du, Leiyue Geng, Yapeng Li, Ziyi Chen, Shizhuang Wang, Like Lou, Haiyuan Peng, Chongke Zheng, Xianzhi Xie, Xiaoming Zheng, Lifang Zhang, Lianguang Shang, Jiaqiang Sun, Qian Qian, Qingwen Yang, Weihua Qiao   +26 more
wiley   +1 more source

Enhancement of antimicrobial activity of pump inhibitors associating drugs

Journal of Infection in Developing Countries, 2019
Introduction: with the continuous emergence of pathogenic resistance to conventional drugs through efflux pumps, increasing efforts are directed toward discovering efflux inhibitory molecules.
Donatella Usai, Matthew Donadu, Alessandra Bua, Paola Molicotti, Stefania Zanetti, Sandra Piras, Paola Corona, Roberta Ibba, Antonio Carta   +8 more
doaj   +1 more source

Heme‐NO Dilates Arteries via Mobilization of NO Moieties From an Intracellular NO Store Within Vascular Smooth Muscle Cells

Advanced Science, EarlyView.
Nitrosyl heme emerges as an extracellular nitrodilator that dilates arteries without crossing the cell membrane. Instead, heme‐NO mobilizes NO moieties from a preformed intracellular NO store within vascular smooth muscle, providing both functional and chemical evidence for the NANOS model, revealing a previously unrecognized mechanism of arterial ...
Taiming Liu, Meijuan Zhang, Lingchao Zhu, Haiyan Ke, Amancio de Souza, Qian Li, Daniel Castella, Nicolai Lehnert, Lubo Zhang, Arlin B. Blood   +9 more
wiley   +1 more source

Drug uptake and efflux.

, 2016
(A-B) Comparison of cell uptake and efflux. A. cell uptake of oxaliplatin. 5637R cells had decreased cell uptake. B: 5637 and 5637R had similar cell efflux rates.
Momchilo Vuyisich (847600), Hongyong Zhang (783167), Amy Wang Pan (847597), Kim Mcmurry (5508017), Sisi Wang (648189), Tiffany M. Scharadin (345930), George Cimino (847599), Michael Malfatti (847601), Cheryl Gleasner (123100), Kenneth Turteltaub (847602), Patrick Chain (362521), Ralph de Vere White (847603), Maike Zimmermann (847596), Paul T. Henderson (847604), Tzu-yin Lin (783168), Chong-xian Pan (2909012), Ruth Vinall (847598), Bin Hu (122268)   +17 more
core   +1 more source

Nanocellulose Alleviates Intrahepatic Cholestasis of Pregnancy via Gut Microbiota‐Mediated Bile Acid Homeostasis

Advanced Science, EarlyView.
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu, Hongjie Dai, Xiaocui Zhong, Qibin Li, Hui Yuan, Yang Yang, Daiyong Huang, Lei Zhang, Rui Ran, Tian He, Yuanzhi Huang, Silas Villas‐Boas, Sergey Tumanov, Richard D. Cannon, Boris Novakovic, Richard Saffery, Yuhao Zhang, Xiaojing Dong, Ting‐Li Han   +18 more
wiley   +1 more source

Potassium Efflux During Apoptosis

BMB Reports, 2002
Apoptosis is responsible for normal tissue homeostasis and isknown to mediate pathological cell loss (Fulton, 1996;Nagata, 1997; Salvesen and Dixit, 1997; Wallach, 1997;Wyllie, 1998). Apoptosis is characterized by morphologicalchanges. These include cell body and nuclear breakdown,chromatin condensation and fragmentation, and formation ofapoptotic ...
Il-Seon, Park, Ja-Eun, Kim
openaire   +3 more sources

Overproduction of efflux pumps caused reduced susceptibility to carbapenem under consecutive imipenem-selected stress in Acinetobacter baumannii

, 2018
Yanpeng Zhang,1,2 Zhuocheng Li,2 Xiaolong He,1 Fanglin Ding,2 Weiqing Wu,2 Yong Luo,2 Bing Fan,2 Hong Cao1 1Department of Microbiology, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University,
Ding F, Li Z, Cao H, Zhang Y, He X, Luo Y, Wu W, Fan B   +7 more
core  

Functional analysis and NMR studies of multi-drug efflux pumps

Efflux pumps play an important role in bacterial multi-drug resistance by actively expelling antibiotics and toxic compounds from the cell. We describe an integrated workflow for the characterisation of inner membrane efflux pumps, consisting of an in ...
Bonev, Boyan B., Goode, Alice, Ralph, Dominic, Blair, Jessica M.A., Yeh, Vivien, Williams, Paul   +5 more
core   +1 more source

Role of Efflux Pumps in the in vitro Development of Ciprofloxacin Resistance in Listeria monocytogenes [PDF]

, 2018
Efflux is a primary fluoroquinolone resistance mechanism in Listeria monocytogenes. In the present study, ciprofloxacin resistant strains were selected by exposure of sensitive strain to progressively increasing concentrations of ciprofloxacin and then ...
Shengdong Ji, Gao, Wujun, Xiaobo Xu, Lei Shi, Ji, Shengdong, Ping Xu, Jiang, Xiaobing, Tao Yu, Shi, Lei, Xu, Ping, Xu, Xiaobo, Wujun Gao, Xiaobing Jiang, Yu, Tao   +13 more
core   +1 more source

Diversity of Pharmaceuticals Enhances Antibiotic Resistance in the Invertebrate Gut via Biofilm‐Mediated Mechanisms

Advanced Science, EarlyView.
Pharmaceutical diversity acts as an independent driver of antibiotic resistance in soil invertebrates. While bulk soil remains unaffected, the collembolan gut microbiome exhibits significant resistance gene enrichment under complex chemical exposure and diurnal warming.
Yi‐Fei Wang, Ya‐Ning Wang, Da Lin, Jia‐Yang Xu, Feng‐Yuan Qi, Hui‐Ling Cui, Hui‐Jie Lu, Min Qiao, Edward Topp, Dong Zhu, Matthias C. Rillig, Yong‐Guan Zhu   +11 more
wiley   +1 more source