Results 121 to 130 of about 272,567 (316)
Efflux-mediated antifungal drug resistance
, 2009 Fungi cause serious infections in the immunocompromised and debilitated, and the incidence of invasive mycoses has increased significantly over the last 3 decades.
Cannon, Richard D. +9 more
core +1 more source
Lymphoid‐Tissue‐on‐Chip Recapitulates Human Antibody Responses In Vitro
Advanced Science, EarlyView.The presented lymphoid‐tissue‐on‐chip system allows culture of primary human tonsil cells at organotypic high density under perfusion for up to 4 weeks, emulates immune response to soluble vaccines and vaccination via peripheral antigen‐presenting cells and represents a useful tool to assess cellular interactions during homeostasis, immune responses ...
Claudia Teufel +15 more
wiley +1 more source
, 2010 Multidrug resistance efflux pumps contribute to antimicrobial and biocide resistance in Staphylococcus aureus. The detection of strains capable of efflux is time-consuming and labor-intensive using currently available techniques. A simple and inexpensive
Susan M. Seo +7 more
core +1 more source
Advanced Science, EarlyView.An activity‐dependent pathway links prefrontal circuit hypoactivity to cognitive impairment. Reduced PVA–mPFC activity upregulates NEPAS, which suppresses PTX3 secretion, leading to impaired angiogenesis, myelin deficits, and memory decline. Rescue is achieved by NEPAS knockdown or chemogenetic circuit activation.
Boya Hu +11 more
wiley +1 more source
Calcium efflux from a heavy sarcotubular fraction
, 1970 Calcium efflux has been measured from two different fractions of rabbit skeletal muscle partially loaded with calcium oxalate, under conditions in which the inward calcium pump is inoperative.
Fairhust, A., Hasselbach, W.
core +1 more source
Advanced Science, EarlyView.A biotin‐modified artificial insertion peptide functionalized three‐dimensional high‐curvature‐TiO2 nano‐interface was engineered in a microfluidic chip to improve the isolation efficiency of small extracellular vesicles (sEVs). This chip balanced affinity, releasability, and extendibility, enabling high‐throughput recovery of sEVs for downstream ...
Le Wang +7 more
wiley +1 more source
Assessing Cholesterol Efflux on Primary Human Trophoblast Cells.
Cholesterol transport across the placenta must be tightly regulated to avoid a deficiency or an oversupply of cholesterol which is transferred from the mother to the fetus.
Albrecht, Christiane +1 more
core +1 more source
Efflux pump inhibitors: a novel approach to combat efflux-mediated drug resistance in bacteria
, 2016 The increasing multi-drug resistance has become a major threat to the public health. Overexpression of multidrug efflux pumps is one of the major mechanisms of drug resistance in bacteria.
Ma, S., Venter, H., Wang, Y.
core +1 more source
Advanced Science, EarlyView.This study elucidates that β‐elemene promotes cellular uptake of L. gasseri‐derived lactate by enhancing the membrane translocation of MCT1 in a CD147‐dependent manner. Intracellular lactate, through the lactylation of RBBP4 at the K26 site, recruits EP300 to the promoter regions of downstream genes (POLD1/POLD3), catalyzing H3K27ac modification.
Jiancheng He +10 more
wiley +1 more source
, 2008 Somvadee Laohavaleeson1, Karen Lolans2,3, John P Quinn2,3,4, Joseph L Kuti1, David P Nicolau11Center for Anti-Infective Research and Development, Hartford Hospital, Hartford, CT, USA; 2John Stroger Hospital, Chicago, IL, USA; 3Chicago Infectious Disease ...
John P Quinn +4 more
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