Results 131 to 140 of about 272,567 (316)

Efflux genes and active efflux activity detection in of methicillin-resistant Staphylococcus aureus (MRSA).

, 2008
Efflux-mediated resistance has been recognized as an important contributor of antibiotic resistance in bacteria, especially in methicillin-resistant Staphylococcus aureus (MRSA) isolates.
Shuhaimi, Mustafa, Ali, Abdul Manaf, Mohtar, Mastura, Zarizal, Suhaili, Saiful, Azmi Johari, Mazurah, Mohamed Isa   +5 more
core   +1 more source

Mapping the “Supply–Demand–Flow” of Ecosystem Services for Ecosystem Management in China

Advanced Science, EarlyView.
This study develops a “supply–demand–flow” framework clarifies how ecosystem services move between regions by distinguishing potential and actual supply and demand. Using integrated biophysical–socioeconomic modeling, nine services in China were mapped.
Yikun Zhang, Yadong Yang, Yongsheng Wang, Guirui Yu   +3 more
wiley   +1 more source

N-acetylaspartate in brain - studies on efflux and function

, 2006
N-acetylaspartate (NAA) is an amino acid derivative present in high concentration in the brain. The function of NAA is still unsettled in spite of 50 years of research.
Tranberg, Mattias
core  

A new technique to measure soil CO2 efflux at constant CO2 concentration

, 2004
A new principle for measuring soil CO2 efflux at constant ambient concentration is introduced. The measuring principle relies on the continuous absorption of CO2 within the system to achieve a constant CO2 concentration inside the soil chamber at ambient
Vedove, Gemini Delle, DELLE VEDOVE, Gemini, Subke, Jens-Arne, Cotrufo, M Francesca, SUBKE J. A., Inglima, Ilaria, INGLIMA I., COTRUFO F., Peressotti, Alessandro   +8 more
core   +1 more source

Targeting Supramolecular Active Complexes of Nav1.7/Nav1.8 to Relieve Chronic Neuropathic Pain

Advanced Science, EarlyView.
In mice and patients with severe chronic neuropathic pain (NP), Nav1.7, Nav1.8, TrkB, and five cytoskeletal proteins form supramolecular active complexes (SMACs) with polygonal lattice structures as noxious signal amplifiers in dorsal root ganglion (DRG) neurons.
Liting Sun, Hang Xian, Yunxin Shi, Taotan Yang, Hongyan Shuai, Wenchao Hu, Siying Fei, Miao Xu, Taoyuan Yang, Ruilong Xia, Ting Wen, Fengting Zhu, Yan Fu, Yang Li, Wei Xia, Ran Qian, Yuanying Liu, Zhicheng Tian, Lamei Li, Qian Zhou, Lize Xiong, Rui Cong, Ceng Luo, Shengxi Wu, Xiafeng Shen, Xin Yu, Rou‐Gang Xie, Changgeng Peng   +27 more
wiley   +1 more source

Description of Two Resistance-Nodulation-Cell Division Efflux Systems Involved in Acquired Antibiotic Resistance: AxySUV in Achromobacter xylosoxidans and AinCDJ in Achromobacter insuavis

Antibiotics
Background/Objectives: Achromobacter xylosoxidans and Achromobacter insuavis are emerging opportunistic pathogens. Several Resistance-Nodulation-cell Division (RND) efflux systems are involved in intrinsic or acquired antibiotic resistance (AxyABM, AxyXY-
Arnaud Magallon, Julien Bador, Thomas Garrigos, Caroline Demeule, Anaïs Chapelle, Véronique Varin, Catherine Neuwirth, Lucie Amoureux   +7 more
doaj   +1 more source

A Chirality‐Converted Bacteriolytic Dodecapeptide Regulates Vibrio‐Induced Polymicrobial Infection and Ameliorates Invasion‐Associated Gut Microbiota Disequilibrium

Advanced Science, EarlyView.
Multidrug‐resistant Vibrio infections are rising rapidly and threaten coastal populations worldwide. This study introduces D‐zp37, a chirality‐engineered antimicrobial peptide with exceptional potency against resistant Vibrio species. D‐zp37 kills planktonic cells, blocks mixed‐species biofilms, disrupts essential bacterial stress responses, and shows ...
Ping Zeng, Qipeng Cheng, Xiaoxu Zhang, Honglan Wang, Jinghan Zhang, Xinyi Ding, Pengfei Zhang, Lanhua Yi, Kwok‐Yin Wong, Kin‐Fai Chan, Sheng Chen, Sharon Shui Yee Leung   +11 more
wiley   +1 more source

Modulation of the Pseudomonas aeruginosa quorum sensing cascade by MexT-regulated factors

mBio
Pseudomonas aeruginosa (Pa) uses quorum sensing (QS), a cell-cell communication system that enables it to sense cell density and alter gene expression.
Andrew Frando, Robert S. Parsek, Jamal Omar, Marie-Christine Groleau, Mylène C. Trottier, Nicole E. Smalley, Eric Déziel, Ajai A. Dandekar   +7 more
doaj   +1 more source

The Development and Pilot Clinical Study of CD147 Targeted Antagonistic Peptide Probe for Tumor Imaging

Advanced Science, EarlyView.
This study establishes [68Ga]Ga‐DOTA‐AP9 as a first‐in‐human CD147‐targeted PET tracer with favorable safety and specific tumor uptake. Tracer accumulation correlates with CD147 expression in patients, enabling noninvasive quantification of CD147‐positive malignancies.
Xiaokun Ma, Rui Guo, Dongfeng Niu, Yufei Song, Zhenyao Zhang, Xiangxi Meng, Lili Mao, Haifeng Huang, Hua Zhu, Zhi Yang, Teli Liu   +10 more
wiley   +1 more source

Selenocompounds as Potent Efflux Pump Inhibitors on Gram-positive Bacteria

In recent years, selenocompounds have gained increasing attention as potential anticancer and antibacterial agents. Several selenoderivatives have been confirmed to act as MDR efflux pump inhibitors, based on their in vitro results against the bacterial ...
Szemerédi, N., Kincses, A., Spengler, G., Domínguez-Álvarez, Enrique, Dózsai, D., Benito-Lama, Miguel, Csonka, Á.   +6 more
core   +1 more source