Histone Modification Complex JMJ704‐HDA709 Negatively Regulates Salinity Tolerance in Rice
This study reveals that the rice histone demethylase JMJ704 interacts with HDA709―a H3K9ac deacetylase characterized herein―to form a chromatin‐modifying complex. Under salt stress, OsWRKY72 recruits this complex through interaction with JMJ704 to target loci, repressing the expression of oxidative stress and salt‐responsive genes via removal of ...
Jing Wang +9 more
wiley +1 more source
Correction for Huang et al., A magnesium efflux transporter required for seed development and eating quality in rice. [PDF]
europepmc +1 more source
High Free‐Volume Imidazole‐Based Ionomers for High‐Temperature Proton Exchange Membrane Fuel Cells
High free‐volume imidazole‐based ionomers (PF4IM‐72) enable enhanced phosphoric acid uptake and efficient proton transport, delivering peak power densities of 0.645 W cm−2 at 160 °C and 0.838 W cm−2 at 200 °C in HT‐PEMFCs. This work highlights a promising platform for next‐generation ionomers with improved high‐temperature performance and stability ...
Ge Chao +7 more
wiley +1 more source
ABCB6 promotes multidrug resistance in leukemia by mediating drug efflux. [PDF]
Jiao Z +10 more
europepmc +1 more source
Adsorption of Forever Chemical Pollutants: The Physical Chemistry of PFAS Near Surfaces
Current adsorption‐based remediation techniques for removing per‐ and polyfluoroalkyl substances (PFAS) from water are limited by knowledge gaps on PFAS behavior near solid surfaces. This review provides a state of the art on theoretical and experimental aspects of PFAS adsorption.
Nada Ben Amor +3 more
wiley +1 more source
Finite element modeling of sarcoplasmic reticular intraluminal Ca<sup>2+</sup> diffusional fluxes during amphibian striated muscle excitation-contraction coupling. [PDF]
Lin KJ +5 more
europepmc +1 more source
Heat Shock Protein 90: From Molecular Chaperone Function to Therapeutic Targeting in Malignancies
In this review, an integrated conceptual framework linking HSP90's molecular chaperone functions to its pathological roles in cancer is proposed. HSP90 serves as a central node that integrates oncogenic signaling, buffers proteotoxic stress, maintains cancer stem cell plasticity, and shapes tumor‐immune interactions, all of which converge to drive ...
Beibei Zhang +4 more
wiley +1 more source
Redefining Antimicrobial Resistance in <i>Acinetobacter baumannii</i>: A Mechanistic Framework Linking Intracellular Antibiotic Activity to Treatment Failure. [PDF]
Elbehiry A +3 more
europepmc +1 more source
Antimicrobial resistance caused by Gram‐negative bacteria remains difficult to overcome due to the protective outer membrane. To address this challenge, a multi‐condition constrained generative AI framework, GenMTAMP is proposed for de novo membrane‐targeting antimicrobial peptide design by integrating physicochemical and spatial structure descriptors.
Jingxiao Yu +5 more
wiley +1 more source
Cationic biocide susceptibility and tolerance-associated genes in clinical, environmental, and commensal Enterococcus isolates. [PDF]
Eldahshan MM +5 more
europepmc +1 more source

