Results 31 to 40 of about 272,567 (316)

Contribution of RND-Type Efflux Pumps in Reduced Susceptibility to Biocides in Acinetobacter baumannii

Antibiotics, 2022
Bacterial efflux pumps are among the key mechanisms of resistance against antibiotics and biocides. We investigated whether differential expression levels of the RND-type efflux pumps AdeABC and AdeIJK impacted the susceptibility to commonly used ...
Christina Meyer, Kai Lucaβen, Stefanie Gerson, Kyriaki Xanthopoulou, Thorsten Wille, Harald Seifert, Paul G. Higgins   +6 more
doaj   +1 more source

phot1 inhibition of ABCB19 primes lateral auxin fluxes in the shoot apex required for phototropism [PDF]

, 2011
It is well accepted that lateral redistribution of the phytohormone auxin underlies the bending of plant organs towards light. In monocots, photoreception occurs at the shoot tip above the region of differential growth.
Titapiwatanakun Boosaree, Lee, O.R., Wendy A. Peer, Lin Jinshan, Murphy, A.S., Kaiserli, Eirini, Ennis, M., Kaiserli, E., Yang Haibing, Lin, Jinshan, Angus S. Murphy, John M Christie, Lin, J., Ritcher, Gregory L., Boosaree Titapiwatanakun, Lee Ok Ran, Lee, Ok Ran, Yang, Haibing, Peer, W.A., Ennis, Margaret, Angus S Murphy, Gregory L. Richter, Adamec Jiri, Thomson, C.E., Richter, G.L., Haibing Yang, Adamec, J., Thomson, Catriona E., Ennis Margaret, Yang, H., Wendy A Peer, Peer, Wendy, Sullivan Stuart, Thomson Catriona E., Titapiwatanakun, B., Catriona E. Thomson, Kaiserli Eirini, Christie, J.M., Christie John M., Peer, Wendy A., Catriona E Thomson, Gregory L Richter, Margaret Ennis, Adamec, Jiri, Sullivan, S., Christie, John M., Peer Wendy A., Richter Gregory L., Eirini Kaiserli, Jiri Adamec, Stuart Sullivan, Richter, Gregory L., Ok Ran Lee, John M. Christie, Murphy Angus S., Jinshan Lin, Sullivan, Stuart, Titapiwatanakun, Boosaree, Murphy, Angus S.   +58 more
core   +1 more source

Efflux, Signaling and Warfare in a Polymicrobial World

Antibiotics, 2023
The discovery void of antimicrobial development has occurred at a time when the world has seen a rapid emergence and spread of antimicrobial resistance, the ‘perfect storm’ as it has often been described.
Ay’sha Moore-Machacek, Antje Gloe, Niall O’Leary, F. Jerry Reen   +3 more
doaj   +1 more source

Understanding adaptation to fluconazole: comparative insights into tolerance and resistance in Saccharomyces cerevisiae and Candida albicans

Frontiers in Cellular and Infection Microbiology
IntroductionAntifungal resistance and tolerance are distinct responses exhibited by fungi when exposed to drugs. While considerable research has focused on azole tolerance in the human pathogen Candida albicans, studies in other fungal species remain ...
Lijun Zheng, Yubo Dong, Jing Wang, Yonghui Jia, Weifang Wang, Yi Xu, Yi Xu, Liangsheng Guo   +7 more
doaj   +1 more source

A Major Facilitator Superfamily Transporter Regulated by the Stress-Responsive Transcription Factor Yap1 Is Required for Resistance to Fungicides, Xenobiotics, and Oxidants and Full Virulence in Alternaria alternata

Frontiers in Microbiology, 2018
Alternaria alternata relies on the ability to produce a host-selective toxin and to detoxify reactive oxygen species to successfully colonize the host. An A.
Hsien-Che Lin, Pei-Ling Yu, Li-Hung Chen, Hsieh-Chin Tsai, Kuang-Ren Chung   +4 more
doaj   +1 more source

Smart pH- and Temperature-Sensitive Micelles Based on Chitosan Grafted with Fatty Acids to Increase the Efficiency and Selectivity of Doxorubicin and Its Adjuvant Regarding the Tumor Cells

Pharmaceutics, 2023
The main factors that determine the low effectiveness of chemotherapy are the low target bioavailability of antitumor drugs and the efflux process. In attempts to overcome this problem, several approaches are proposed here.
Igor D. Zlotnikov, Dmitriy A. Streltsov, Alexander A. Ezhov, Elena V. Kudryashova   +3 more
doaj   +1 more source

Herb-Drug Pharmacokinetic Interactions: Transport and Metabolism of Indinavir in the Presence of Selected Herbal Products

Molecules, 2015
Patients receiving anti-retroviral drug treatment are sometimes simultaneously taking herbal remedies, which may result in pharmacokinetic herb-drug interactions.
Carlemi Calitz, Chrisna Gouws, Joe Viljoen, Jan Steenekamp, Lubbe Wiesner, Efrem Abay, Josias Hamman   +6 more
doaj   +1 more source

Efflux-mediated antimicrobial resistance [PDF]

Journal of Antimicrobial Chemotherapy, 2005
Antibiotic resistance continues to plague antimicrobial chemotherapy of infectious disease. And while true biocide resistance is as yet unrealized, in vitro and in vivo episodes of reduced biocide susceptibility are common and the history of antibiotic resistance should not be ignored in the development and use of biocidal agents.
openaire   +2 more sources

The roles of different pathways in the release of cholesterol from macrophages

Journal of Lipid Research, 2007
Cholesterol efflux occurs by different pathways, including transport mediated by specific proteins. We determined the effect of enriching cells with free cholesterol (FC) on the release of FC to human serum.
Maria Pia Adorni, Francesca Zimetti, Jeffrey T. Billheimer, Nan Wang, Daniel J. Rader, Michael C. Phillips, George H. Rothblat   +6 more
doaj   +1 more source

Heterologous expression of the yeast arsenite efflux system ACR3 improves Arabidopsis thaliana tolerance to arsenic stress [PDF]

, 2012
Arsenic contamination has a negative impact on crop cultivation and on human health. As yet, no proteins have been identified in plants that mediate the extrusion of arsenic. Here, we heterologously expressed the yeast (Saccharomyces cerevisiae) arsenite
Maathuis, F. J. M., Ali, W., Zhao, F-J., Isner, J-C., Liu, W., Isayenkov, S. V.   +5 more
core   +1 more source