Results 71 to 80 of about 427,575 (339)
ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells
FEBS Open Bio, EarlyView.Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori +8 more
wiley +1 more source
Dalcetrapib and anacetrapib differently impact HDL structure and function in rabbits and monkeys
Journal of Lipid Research, 2017 Inhibition of cholesteryl ester transfer protein (CETP) increases HDL cholesterol (HDL-C) levels. However, the circulating CETP level varies and the impact of its inhibition in species with high CETP levels on HDL structure and function remains poorly ...
Mathieu R. Brodeur +11 more
doaj +1 more source
Proximate controls on semiarid soil greenhouse gas fluxes across 3 million years of soil development [PDF]
, 2015 Soils are important sources and sinks of three greenhouse gases (GHGs): carbon dioxide (CO2), methane (CH4), and nitrous oxide (N2O). However, it is unknown whether semiarid landscapes are important contributors to global fluxes of these gases, partly ...
Hart, SC +3 more
core +1 more source
Species-specific effects of elevated ozone on wetland plants and decomposition processes [PDF]
, 2010 Seven species from two contrasting wetlands, an upland bog and a lowland rich fen in North Wales, UK, were exposed to elevated ozone (150 ppb for 5 days and 20 ppb for 2 days per week) or low ozone (20 ppb) for four weeks in solardomes.
Freeman, Chris +2 more
core +1 more source
The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
Effect of a novel nutraceutical combination on serum lipoprotein functional profile and circulating PCSK9 [PDF]
, 2017 BACKGROUND: A beneficial effect on cardiovascular risk may be obtained by improving lipid-related serum lipoprotein functions such as high-density lipoproteins (HDLs) cholesterol efflux capacity (CEC) and serum cholesterol loading capacity (CLC) and by ...
Adorni, Maria Pia +7 more
core +3 more sources
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Molecules, 2017 The potential role of non-antibiotic medicinal products in the treatment of multidrug-resistant Gram-negative bacteria has recently been investigated. It is highly likely that the presence of efflux pumps may be one of the reasons for the weak activity ...
Agnieszka E. Laudy +2 more
doaj +1 more source
The PIN-FORMED (PIN) protein family of auxin transporters [PDF]
, 2009 The PIN-FORMED (PIN) proteins are secondary transporters acting in the efflux of the plant signal molecule auxin from cells. They are asymmetrically localized within cells and their polarity determines the directionality of intercellular auxin flow.
Friml, Jiri +6 more
core +3 more sources
Potassium Efflux During Apoptosis
BMB Reports, 2002 Apoptosis is responsible for normal tissue homeostasis and isknown to mediate pathological cell loss (Fulton, 1996;Nagata, 1997; Salvesen and Dixit, 1997; Wallach, 1997;Wyllie, 1998). Apoptosis is characterized by morphologicalchanges. These include cell body and nuclear breakdown,chromatin condensation and fragmentation, and formation ofapoptotic ...
Il-Seon, Park, Ja-Eun, Kim
openaire +3 more sources