Results 101 to 110 of about 71,112 (299)

Active efflux systems in the solvent-tolerant bacterium Pseudomonas putida S12

, 2002
The aim of the research presented in this thesis was to study the molecular mechanisms of organic solvent tolerance in Pseudomonas putida S12. This bacterium is capable of growth at saturated solvent concentrations, which are lethal to normal bacteria ...
Kieboom, J.
core  

Types and Mechanisms of Efflux Pump Systems and the Potential of Efflux Pump Inhibitors in the Restoration of Antimicrobial Susceptibility, with a Special Reference to Acinetobacter baumannii

Pathogens
Bacteria express a plethora of efflux pumps that can transport structurally varied molecules, including antimicrobial agents and antibiotics, out of cells.
Kira M. Zack, Trent Sorenson, Suresh G. Joshi   +2 more
doaj   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

The Inhibitory Effect of Artemisa quttensis Extract on norA Efflux Pump in Ciprofloxacin Resistant Staphylococcus aureus Strains Using Ethidium Bromide and Real-Time PCR Methods

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2017
Background and Objectives: norA efflux pump is one of the mechanisms of ciprofloxacin resistance in Staphylococcus aureus strains, and finding natural herbal compounds with the ability to inhibit efflux pumps is one of the recent challenges.
Amir Mirzaie, Ali Asghar Bagheri Kashtali, Hassan Noorbazargan, Seyed Ataollah Sadat Shandiz   +3 more
doaj  

Photodynamic Priming and Minocycline Overcome Chemoresistance by Reprogramming the Pancreatic Tumor Immune Microenvironment In Vivo

Advanced Science, EarlyView.
Dual priming with minocycline and photodynamic priming reprograms the pancreatic tumor microenvironment to overcome chemoresistance. By suppressing DNA repair enzyme Tdp1, inducing photooxidative damage, and enhancing irinotecan delivery via light‐activated nanoencapsulation, this strategy remodels the tumor microenvironment and drives immune ...
Fernanda V. Cabral, Jose Quilez‐Alburquerque, Olivia Mooradian, Shivendran Vytheswarran, Badri Parshad, Girgis Obaid, Huang‐Chiao Huang, Tayyaba Hasan   +7 more
wiley   +1 more source

Evaluation of efflux pump activity of multidrug-resistant Salmonella Typhimurium isolated from poultry wet markets in India

, 2019
Prasanna Vadhana Anbazhagan,1 Prasada Rao Thavitiki,2 Manasa Varra,2 Latchumikanthan Annamalai,3 Ramya Putturu,4 Venkateswara Rao Lakkineni,4 Pavan Kumar Pesingi41Department of Veterinary Microbiology, College of Veterinary Science, Sri Venkateswara ...
Putturu R, Anbazhagan PV, Lakkineni VR, Varra M, Annamalai L, Thavitiki PR, Pesingi PK   +6 more
core  

Virtual screening and biological activity evaluation of novel efflux pump inhibitors targeting RE-CmeB in Campylobacter spp.

One Health Advances
RE-CmeABC is a variant of the efflux pump CmeABC in the major zoonotic pathogen Campylobacter, which is much more potent in conferring resistance to various antibiotics for the treatment of Campylobacter infections in both veterinary and medical clinics.
Shihong Li, Cheng Zhang, Wenjun Li, Shuigen Wan, Jin Kang, Yong Liu, Hexiang Huang, Hao Li, Longhua Yang, Yanhong Shang, Chenglong Li, Xiangdang Du, Hong Yao   +12 more
doaj   +1 more source

Breaking the Bottleneck in Limit of Detection of Surface Refractive Index Sensing by Harnessing Meta‐Waveguide Microring Resonators

Advanced Science, EarlyView.
Mode splitting in meta‐waveguide microring resonators (MWMRs) effectively suppresses baseline drift and measurement noise while maintaining high refractive‐index sensitivity. This reflection‐induced mode splitting strategy enables quantitative detection of ultra‐weak surface perturbations and establishes MWMRs as a robust, drift‐immune platform for ...
Wanxin Li, Jiewen Li, Rui Li, Gina Jinna Chen, Perry Ping Shum, Yi Zou, Ray T. Chen, Yongkang Dong, Xiaochuan Xu   +8 more
wiley   +1 more source

Verapamil and its metabolite norverapamil inhibit the Mycobacterium tuberculosis MmpS5L5 efflux pump to increase bedaquiline activity

Bedaquiline is the cornerstone of a new regimen for the treatment of drug-resistant tuberculosis. However, its clinical use is threatened by the emergence of bedaquiline-resistant strains of Mycobacterium tuberculosis.
Cook, Gregory M., Chrisp, Michael T., Waller, Natalie J. E., McNeil, Matthew B., Edelstein, Paul H., Jowsey, William, Cheung, Chen-Yi, Troll, Mark, Fountain, Adam J., Ramakrishnan, Lalita, Waller, Natalie J.E., Cheung, Chen Yi, https://orcid.org/   +12 more
core   +1 more source

The effect of carbonyl cyanide m-chlorophenyl-hydrazine on antibiotic susceptibility in MDR Enterobacteriaceae isolates in Babylon, Iraq

Medical Journal of Babylon
Background: One of the efflux pump inhibitors is carbonyl cyanide 3-chlorophenylhydrazone (CCCP) that has often been found to increase the susceptibility of a number of multi-drug resistant (MDR) MDR bacteria, isolated from human clinical specimens ...
Hadeel Qasim Jebur, Alaa H. Al-Charrakh
doaj   +1 more source