Results 61 to 70 of about 119,180 (205)

CmeABC multidrug efflux pump contributes to antibiotic resistance and promotes 'Campylobacter jejuni' survival and multiplication in 'Acanthamoeba polyphaga' [PDF]

, 2017
Campylobacter jejuni is a foodborne pathogen recognized as the leading cause of human bacterial gastroenteritis. The wide use of antibiotics in medicine and in animal husbandry has led to an increased incidence of antibiotic resistance in Campylobacter ...
Alan M. Seddon, Alvarez-Ortega, Amritha Ramesh, Ana Vieira, Anacarso, Andrew J. McBain, Andrey V. Karlyshev, Axelsson-Olsson, Axelsson-Olsson, Axelsson-Olsson, Backert, Bacon, Baldvinsson, Bare, Bare, Barker, Baugh, Blanco, Bolton, Bronowski, Buckley, Bui, Bui, Cagliero, Chu, Cirillo, Dasti, Dirks, Drevets, Elsinghorst, Fernando, Goni, Gregson, Griekspoor, Hirakata, Hofreuter, Iovine, Johnson, Joshua, Karlyshev, Karlyshev, Lambrecht, Lehri, Lin, Lin, Lugert, Mavri, Olofsson, Olsson, Padilla, Piddock, Poole, Sandstrom, Siddiqui, Siddiqui, Siddiqui, Sifre, Snelling, Snelling, Stintzi, Sun, Thomas, Tosetti, Vaerewijck, Vieira, Webber, Wijdicks, Winiecka-Krusnell, Yao, Young   +69 more
core   +1 more source

Function and Inhibitory Mechanisms of Multidrug Efflux Pumps

Frontiers in Microbiology, 2021
Multidrug efflux pumps are inner membrane transporters that export multiple antibiotics from the inside to the outside of bacterial cells, contributing to bacterial multidrug resistance (MDR). Postgenomic analysis has demonstrated that numerous multidrug
Kunihiko Nishino, Seiji Yamasaki, Ryosuke Nakashima, Martijn Zwama, Mitsuko Hayashi-Nishino   +4 more
doaj   +1 more source

Comparative genomic analysis of Geobacter sulfurreducens KN400, a strain with enhanced capacity for extracellular electron transfer and electricity production [PDF]

, 2012
Peer ...
Aklujkar, Muktak, Butler, Jessica E, Lovley, Derek R, Young, Nelson D   +3 more
core   +4 more sources

Biofilm Formation and the Role of Efflux Pumps in ESKAPE Pathogens

Microorganisms
Nosocomial infections caused by ESKAPE pathogens represent a significant burden to global health. These pathogens may exhibit multidrug resistance (MDR) mechanisms, of which mechanisms such as efflux pumps and biofilm formation are gaining significant ...
Trent R. Sorenson, Kira M. Zack, Suresh G. Joshi   +2 more
doaj   +1 more source

Enhanced Efficacy of Ciprofloxacin and Tobramycin against Staphylococcus aureus When Combined with Corydalis Tuber and Berberine through Efflux Pump Inhibition

Antibiotics
One way that bacteria develop antibiotic resistance is by reducing intracellular antibiotic concentrations through efflux pumps. Therefore, enhancing the efficacy of antibiotics using efflux pump inhibitors provides a way to overcome this type of ...
Yena Seo, Minjun Kim, Tae-Jong Kim
doaj   +1 more source

Microbial Communities of the Providence River [PDF]

, 2015
The Providence River has been industrialized for over one-hundred years. Industries such as oil storage and metal recycling facilities have left high levels of pollutant metals, including lead (Pb), in the soil and water.
Kratch, Jacqueline
core   +1 more source

Dominant Role of Nucleotide Substitution in the Diversification of Serotype 3 Pneumococci over Decades and during a Single Infection [PDF]

, 2013
Streptococcus pneumoniae of serotype 3 possess a mucoid capsule and cause disease associated with high mortality rates relative to other pneumococci. Phylogenetic analysis of a complete reference genome and 81 draft sequences from clonal complex 180, the
Barquist, L, Bentley, SD, Browall, S, Croucher, NJ, Dordel, J, Feltwell, T, Fookes, MC, Gould, KA, Harris, SR, Henriques-Normark, B, Hinds, J, Inverarity, D, Mitchell, AM, Mitchell, TJ, Normark, S, Parkhill, J, Salter, SJ, Zemlickova, H   +17 more
core   +4 more sources

Microbial Primer: Multidrug efflux pumps.

Microbiology (Reading, England), 2023
Multidrug efflux pumps are molecular machines that sit in the bacterial cell membrane and pump molecules out from either the periplasm or cytoplasm to outside the cell. While involved in a variety of biological roles, they are primarily known for their contribution to antibiotic resistance by limiting the intracellular accumulation of antimicrobial ...
Siasat, Pauline Ann, Blair, Jessica M. A.   +1 more
openaire   +2 more sources

Functional characterization and discovery of modulators of SbMATE, the agronomically important aluminium tolerance transporter from Sorghum bicolor. [PDF]

, 2017
About 50% of the world's arable land is strongly acidic (pH ≤ 5). The low pH solubilizes root-toxic ionic aluminium (Al3+) species from clay minerals, driving the evolution of counteractive adaptations in cultivated crops.
Chang, Geoffrey, Doshi, Rupak, Garza, Denisse M, Kochian, Leon V, McGrath, Aaron P, Piñeros, Miguel, Szewczyk, Paul   +6 more
core   +3 more sources

Structure of the AcrAB–TolC multidrug efflux pump [PDF]

Nature, 2014
The capacity of numerous bacterial species to tolerate antibiotics and other toxic compounds arises in part from the activity of energy-dependent transporters. In Gram-negative bacteria, many of these transporters form multicomponent 'pumps' that span both inner and outer membranes and are driven energetically by a primary or secondary transporter ...
Du, Dijun, Wang, Zhao, James, Nathan R., Voss, Jarrod E., Klimont, Ewa, Ohene-Agyei, Thelma, Venter, Henrietta, Chiu, Wah, Luisi, Ben F.   +8 more
openaire   +3 more sources