Results 201 to 210 of about 50,413 (250)

Inhibition of efflux pumps by FDA-approved drugs oxiconazole and sertaconazole restores antibiotic susceptibility in multidrug-resistant <i>S. aureus</i>. [PDF]

Antimicrob Agents Chemother
Ojha S, Chatterjee P, Beuria TK.
europepmc   +1 more source

The potential impact of H1 antihistamines on clinical outcomes in NSCLC patients undergoing EGFR‐TKIs treatment

British Journal of Clinical Pharmacology, EarlyView.
Background Epidermal growth factor receptor–tyrosine kinase inhibitors (EGFR‐TKIs) have substantially improved outcomes in non‐small cell lung cancer (NSCLC); however, the development of treatment resistance remains a major clinical challenge. This study examines the association between concomitant prescriptions of H1‐antihistamines (H1AHs) and ...
Van Thuan Nguyen, Ngoc Hoang Le, Nhu Quynh Phan, Toan Trung Duong, Le Thi Anh Thu, Hsuan‐Chia Yang, Chih‐Wei Huang, Min‐Huei Hsu, Jason C. Hsu, Chien‐Tien Su, Phung‐Anh Nguyen   +10 more
wiley   +1 more source

Whole-Genome Sequence Analysis to Assess Mutations in Efflux Pumps in <i>Mycobacterium tuberculosis</i>: The Influence in Drug Resistance. [PDF]

Microorganisms
Chimal-Muñoz M, Pérez-Martínez DE, Bermúdez Hernández GA, Mejía-Ponce PM, Licona-Cassani C, Muñiz-Salazar R, Montero H, Zenteno-Cuevas R.   +7 more
europepmc   +1 more source

Enhancing the Secretion Systems: Genetic Engineering of Super Bioagents for Effective Plant Disease Control

Biotechnology and Bioengineering, EarlyView.
Genetic engineering (GE) overcomes BCA limits, enabling robust, scalable crop protection. “Super Bioagents” (SBs) use optimized SSs to enhance bioactive molecule delivery. Optimizing SSs enhance precise, sustainable effector deployment for stable disease suppression. SBs use microbiome‐informed design for scalable, next‐gen sustainable crop protection.
Michael Dare Asemoloye
wiley   +1 more source

Targeting efflux pumps prevents the multi-step evolution of high-level resistance to fluoroquinolone in Pseudomonas aeruginosa. [PDF]

Microbiol Spectr
Yu X-Q, Yang H, Feng H-Z, Hou J, Tian J-Q, Niu S-M, You C-G, Tao X-Y, Zhang S-P, Wang Z-P, He Y-X.   +10 more
europepmc   +1 more source

Artificial Cell Catalysts for Biotransformation: Design Principles and Process Integration

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Artificial cell catalysts are emerging as programmable biocatalytic platforms for sustainable molecular conversion. By reconstituting enzymes and functional modules within synthetic compartments, they combine the selectivity of biological catalysis with the design flexibility of synthetic materials.
Iori Kobayashi, Shogo Yoshimoto, Katsutoshi Hori   +2 more
wiley   +1 more source

Helicobacter pylori Efflux Pumps: A Double-Edged Sword in Antibiotic Resistance and Biofilm Formation. [PDF]

Int J Mol Sci
Krzyżek P.
europepmc   +1 more source

Efflux Pumps and Porins Enhance Bacterial Tolerance to Phenolic Compounds by Inhibiting Hydroxyl Radical Generation. [PDF]

Microorganisms
Sui X, Guo L, Bao Z, Xian M, Zhao G.
europepmc   +1 more source

Virulence genes, efflux pumps, and molecular typing of Klebsiella pneumoniae isolates from North Iran. [PDF]

AMB Express
Birgani AH, Goli HR, Siadat SD, Fateh A, Nikbin VS, Sakhaee F, Ashrafian F, Haghshenas MR, Gholami M.   +8 more
europepmc   +1 more source

Identification of Compounds With Potential Dual Inhibitory Activity Against Drug Efflux Pumps in Resistant Cancer Cells and Bacteria: Protocol for a Systematic Review. [PDF]

JMIR Res Protoc
Beleva E, Diukendjieva A, Pajeva I, Tsakovska I.   +3 more
europepmc   +1 more source