Results 121 to 130 of about 54,202 (287)
An Embodied Paper‐Based Microfluidic Al‐Air Battery for Enduring Untethered Insect‐Scale Robots
Advanced Science, EarlyView.This work presents a centimeter‐scale microfluidic aluminum–air battery (MFAAB) with dual‐surface anode and F−‐mediated byproduct decomposition. The design enables a high capacity of 2697.05 mAh/g Al and delivers tens of milliwatts to power LEDs, motors, and a toy car.
Yun Yang +5 more
wiley +1 more source
Combating Multi-drug Resistant Mycobacterium Species by Efflux Pump Inhibitors: Contemporary Trends
BIO IntegrationTuberculosis (TB) is caused by Mycobacterium tuberculosis (M.tb) complex (MTBC), which includes M.tb as one of the causative bacteria. In contrast, non-tuberculous mycobacteria (NTM) refers to Mycobacterium spp. that do not cause TB or leprosy (MTBC spp.,
Gautam Kumar +6 more
doaj +1 more source
Advanced Science, EarlyView.A senolytic sonovaccine platform (SenoVac) is developed, in which senescent cell‐derived vesicles serve as broad senescent cell antigen reservior. The “2‐step” click chemistry strategy for effective lymph node delivery, and ultrasound‐triggered endosomal escape to boost cross‐presentation, ensures efficient senescent cell clearance and disease ...
Liang Zhang +10 more
wiley +1 more source
Efflux pumps as antimicrobial resistance mechanisms
Annals of Medicine, 2007 Antibiotic resistance continues to hamper antimicrobial chemotherapy of infectious disease, and while biocide resistance outside of the laboratory is as yet unrealized, in vitro and in vivo episodes of reduced biocide susceptibility are not uncommon.
openaire +2 more sources
Expression of three efflux pumps
, 2002 Drug efflux is a major mechanism of resistance to drugs in both cancer cells and pathogenic microorganisms. Consequently, there is an urgent need to understand the structure, function, and expression of the multidrug resistance pumps involved so that ...
Wheeler, David Michael
core
Advanced Science, EarlyView.Antimicrobial resistance caused by Gram‐negative bacteria remains difficult to overcome due to the protective outer membrane. To address this challenge, a multi‐condition constrained generative AI framework, GenMTAMP is proposed for de novo membrane‐targeting antimicrobial peptide design by integrating physicochemical and spatial structure descriptors.
Jingxiao Yu +5 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT Vascularization remains a major obstacle in tissue engineering. Here, we introduce a bioprinting strategy to generate centimeter‐scale, self‐organizing “mother vessel” constructs from iPSC‐derived hiMPCs. By optimizing bioink composition, printing was accomplished in a single‐step approach. Within one week, hiMPCs differentiated into both CD31+
Leyla E. Dogan +5 more
wiley +1 more source
npj Antimicrobials and ResistanceMultidrug efflux pumps have been found to play a crucial role in drug resistance in bacteria and eukaryotes. In this study, we investigated the presence of functional multidrug and toxic compound extrusion (MATE) efflux pumps, inferred from whole genome ...
Asma A. Fakhoury +7 more
doaj +1 more source
The aim of the study was investigate the occurrence of multidrug resistance efflux pumps genes in local clinical isolates of Salmonella sp and try to apply efflux inhibitor for phenotypic detection besides their possibly future therapeutic uses to retain
Nuha Joseph Kandala +1 more
core +2 more sources
Identification of three outer membrane channels of RND efflux pumps.
, 2013 Identification of three outer membrane channels of RND efflux pumps.
Thomas Poyot (135820) +9 more
core +1 more source