Results 21 to 30 of about 985,633 (279)
Role of efflux pumps in reduced susceptibility to tigecycline in Acinetobacter baumannii
New Microbes and New Infections, 2019 Acinetobacter baumannii is an important human pathogen responsible for a various type of infections. These bacterial strains are generally resistant to numerous antibiotics.
S.H. Ardehali +5 more
doaj +2 more sources
Effects of efflux pumps on antifungal activity of chitosan against Candida albicans [PDF]
Journal of Oral MicrobiologyBackground Antifungal resistance is a major problem, commonly caused by drug-efflux pump overexpression. To evaluate if chitosan could be effective in drug-resistant Candida infections, we investigated the effects of efflux pumps on antifungal activity ...
Sureeporn Muangsawat +5 more
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Microbiology, 2023 The problem of antibiotic resistance among pathogenic bacteria has reached a crisis level. The treatment options against infections caused by multiple drug-resistant bacteria are shrinking gradually. The current pace of the discovery of new antibacterial
Amit Gaurav +4 more
semanticscholar +1 more source
Role of Efflux Pumps on Antimicrobial Resistance in Pseudomonas aeruginosa
International Journal of Molecular Sciences, 2022 Antimicrobial resistance is an old and silent pandemic. Resistant organisms emerge in parallel with new antibiotics, leading to a major global public health crisis over time.
A. Lorusso +4 more
semanticscholar +1 more source
EFFLUX PUMPS AS A PHARMACOLOGICAL TARGET TO COMBAT ANTIBIOTIC RESISTANCE
Медична наука України, 2023 Backround. Antibiotic resistance is the resistance of bacteria to antimicrobial drugs to which they were previously sensitive. A particular danger is the spread of multidrug-resistant healthcare-associated infections of "ESKAPE" group.
M.V. Khaitovych
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PLoS Biology, 2022 Bacteria have membrane-spanning efflux pumps to secrete toxic compounds ranging from heavy metal ions to organic chemicals, including antibiotic drugs.
Christopher J Stubenrauch +3 more
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Susceptibility Tests and Predictions of Transporter Profile in Serratia Species
Microorganisms, 2022 Disinfectants and biosecurity are critically important to control microbial diseases. Resistance to disinfectants compromises sectors such as agriculture and healthcare systems.
Gunther J. Staats +3 more
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Microbiology, 2023 Drug efflux pumps transport antimicrobial agents out of bacteria, thereby reducing the intracellular antimicrobial concentration, which is associated with intrinsic and acquired bacterial resistance to these antimicrobials.
S. Yamasaki +4 more
semanticscholar +1 more source
mSystems, 2021 Multidrug resistance (MDR) efflux pumps are involved in bacterial intrinsic resistance to multiple antimicrobials. Expression of MDR efflux pumps can be either constitutive or transiently induced by various environmental signals, which are typically ...
Di-Yin Li +7 more
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Physiological Functions of Bacterial "Multidrug" Efflux Pumps.
Chemical Reviews, 2021 Bacterial multidrug efflux pumps have come to prominence in human and veterinary pathogenesis because they help bacteria protect themselves against the antimicrobials used to overcome their infections.
P. Henderson +5 more
semanticscholar +1 more source