Results 51 to 60 of about 48,983 (153)
Mechanisms of RND multidrug efflux pumps [PDF]
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2009 RND (Resistance-Nodulation-Division) family transporters are widespread especially among Gram-negative bacteria, and catalyze the active efflux of many antibiotics and chemotherapeutic agents. They have very large periplasmic domains, and form tripartite complexes with outer membrane channels and periplasmic adaptor proteins.
Hiroshi, Nikaido, Yumiko, Takatsuka
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The putative drug efflux systems of the Bacillus cereus group. [PDF]
PLoS ONE, 2017 The Bacillus cereus group of bacteria includes seven closely related species, three of which, B. anthracis, B. cereus and B. thuringiensis, are pathogens of humans, animals and/or insects.
Karl A Hassan +11 more
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Role of H- and D- MATE-type transporters from multidrug resistant clinical isolates of Vibrio fluvialis in conferring fluoroquinolone resistance. [PDF]
PLoS ONE, 2012 BACKGROUND: The study seeks to understand the role of efflux pumps in multidrug resistance displayed by the clinical isolates of Vibrio fluvialis, a pathogen known to cause cholera-like diarrhoea.
Priyabrata Mohanty +2 more
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Evidence of an Efflux Pump in Serratia marcescens [PDF]
Microbial Drug Resistance, 2000 Spontaneous mutants resistant to fluoroquinolones were obtained by exposing Serratia marcescens NIMA (wild-type strain) to increasing concentrations of ciprofloxacin both in liquid and on solid media.
Berlanga Herranz, Mercedes +4 more
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Inhibitors of bacterial efflux pumps that also inhibit efflux pumps of cancer cells.
Anticancer research, 2012 Bacteria and cancer cells frequently increase their resistance to chemotherapeutics as a consequence of therapy. Whenever studied, refractory response to chemotherapy is due to the over-expression of efflux pumps that render the bacterium or cancer cell resistant not only to the agent used for therapy, but to many, if not all other agents as well ...
Amaral, Leonard +6 more
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Synthetic feedback loop model for increasing microbial biofuel production using a biosensor
Frontiers in Microbiology, 2012 Current biofuel production methods use engineered bacteria to break down cellulose and convert it to biofuel. A major challenge in microbial fuel production is that increasing biofuel yields can be limited by the toxicity of the biofuel to the organism ...
Mary eHarrison, Mary eDunlop
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Restoration of Antibiotic Effectiveness with P. hartigii Extract Against Multidrug-Resistant E. coli
Medical Sciences ForumAntibiotic resistance poses a critical threat to global health, largely driven by bacterial efflux pumps that expel antibiotics and reduce their efficacy.
Eda Altınöz +2 more
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Frontiers in MicrobiologyMulti-drug resistance (MDR) bacteria pose a significant global health challenge, primarily driven by the activity of multi-drug efflux pumps and their intimate coupling to bacterial membrane bioenergetics.
Ajay Pratap Singh Hada +5 more
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Microbiology SpectrumCryptococcosis is a systemic mycosis affecting immunocompromised individuals (mainly C. neoformans) and immunocompetent hosts (mainly C. gattii). Effective treatment remains challenging due to antifungal resistance, driven by efflux pumps, target enzyme ...
Gabriel Rezende Pimenta +6 more
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Iranian Journal of MicrobiologyBackground and Objectives: Pseudomonas aeruginosa (P. aeruginosa), a multidrug-resistant bacterium, represents a considerable risk in healthcare environments owing to its capacity to induce various infections. The resistance of P.
Fahad Ullah +9 more
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