Results 151 to 160 of about 86,304 (284)

Wearable Tailored Passive Radiative Cooling Textile for Flexible Electronic Integration

Advanced Science, EarlyView.
A scalable, additive‐free wearable tailored passive radiative cooling textile (WRCT) with hierarchically structured fibers delivers exceptional thermal management, combining >95% solar reflectance, 0.96 mid‐infrared emissivity, and ultralow thermal conductivity (0.041 W/m·K).
Lung Chow, Jianpeng Zhang, Zehua Peng, Denglin Ye, Binbin Zhang, Jian Li, Wooyoung Park, Chentao Du, Xingcan Huang, Chun Ki Yiu, Yuze Qiu, Jingkun Zhou, Zhenlin Chen, Yuyu Gao, Weibin Zhu, Pengcheng Wu, Guangyao Zhao, Qiang Zhang, Yuan Guo, Zuowei Sun, Zhan Shen, Shuaiqi Ren, Sang Min Won, Jiyu Li, Xinge Yu   +24 more
wiley   +1 more source

Evaluation of the Phenotypic and Molecular Pattern of Efflux Pumps in Clinical Isolates of Methicillin-resistant Staphylococcus aureus

پزشکی بالینی ابن سینا, 2017
Background and Objective: Efflux pumps are regarded as one of the most important mechanisms of antibiotic resistance in this era. Staphylococcus aureus is one of the bacterial groups with efflux pumps. The pumps’ activity is coded by specific genes.
J Ghaderkhani, H Tahmasebi, B Zeyni, S Dehbashi, MR Arabestani   +4 more
doaj  

Multimodal Multiorgan‐on‐a‐Chip Platform for Probing Liver‐Tumor Interactions and Advancing Prodrug Screening

Advanced Science, EarlyView.
This work introduces a multimodal multi‐OoC platform that overcomes current limitations in liver‐tumor interaction studies and prodrug screening. By integrating dynamic microfluidic circuits, electrochemical sensing, and mass analysis, this platform enables non‐invasive, longitudinal monitoring of drug metabolism and hepatotoxicity, offering a ...
Dan Wang, Yisong Huang, Weijian Zhao, Tian Chen, Siyu Bai, Denghui Guo, Mengying Wang, Yaoyao Zhao, Liang Zhao, Guangsheng Guo, Xiayan Wang   +10 more
wiley   +1 more source

Highly Efficient Extraction of 212 Pb/212Bi from the Decay Chain of 232Th‐Based on Anion Exchange in Bromide Medium

Advanced Science, EarlyView.
This work provides an effective strategy for selectively extracting 212Pb and 212Bi from the decay chain of 232Th as well as its mechanism illustration. Using the novel strategy, 2.07 MBq of 212Pb is successfully separated from 232Th and its daughters, which enables the supply of 212Pb/212Bi directly from the abundant natural thorium resource to be ...
Lifeng Chen, Wannian Feng, Yuezhou Wei, Xuexiang He, Shaoying Wang, Zhongyuan Zhou, Qiang Wu, Ningchao Zheng, Xiangbiao Yin, Wenlong Li, Lingling Su, Shunyan Ning   +11 more
wiley   +1 more source

A FAP‐Targeted SMDC Platform Enables Synergistic Radionuclide–Chemotherapy with PET‐Guided Evaluation

Advanced Science, EarlyView.
A fibroblast activation protein (FAP)‐targeted small molecule–drug conjugate (SMDC) platform is developed to integrate PET imaging with synergistic radionuclide–chemotherapy. Linker chemistry governs stability, exposure, and tolerability, with the VC linker providing superior in vivo performance.
Ruitao Yang, Hongxin Li, Zexin Xu, Baocheng Chen, Ningjie Li, Yuhua Zhong, Kongzhen Hu   +6 more
wiley   +1 more source

Photodynamic Priming and Minocycline Overcome Chemoresistance by Reprogramming the Pancreatic Tumor Immune Microenvironment In Vivo

Advanced Science, EarlyView.
Dual priming with minocycline and photodynamic priming reprograms the pancreatic tumor microenvironment to overcome chemoresistance. By suppressing DNA repair enzyme Tdp1, inducing photooxidative damage, and enhancing irinotecan delivery via light‐activated nanoencapsulation, this strategy remodels the tumor microenvironment and drives immune ...
Fernanda V. Cabral, Jose Quilez‐Alburquerque, Olivia Mooradian, Shivendran Vytheswarran, Badri Parshad, Girgis Obaid, Huang‐Chiao Huang, Tayyaba Hasan   +7 more
wiley   +1 more source

Breaking the Bottleneck in Limit of Detection of Surface Refractive Index Sensing by Harnessing Meta‐Waveguide Microring Resonators

Advanced Science, EarlyView.
Mode splitting in meta‐waveguide microring resonators (MWMRs) effectively suppresses baseline drift and measurement noise while maintaining high refractive‐index sensitivity. This reflection‐induced mode splitting strategy enables quantitative detection of ultra‐weak surface perturbations and establishes MWMRs as a robust, drift‐immune platform for ...
Wanxin Li, Jiewen Li, Rui Li, Gina Jinna Chen, Perry Ping Shum, Yi Zou, Ray T. Chen, Yongkang Dong, Xiaochuan Xu   +8 more
wiley   +1 more source

Tyrosinase Driven‐Intracellular Polymerization of a Porphyrin Derivative Induced Immunogenic Death of Melanoma Cells and Strengthened Photodynamic Therapy

Advanced Science, EarlyView.
This study uses tyrosinase, which is highly expressed in melanoma, to drive porphyrins to polymerize and self‐assemble within tumor cells to form retented microstructures. This process induces immunogenic death and activates immune responses (M1 macrophages, dendritic cells, CD8+T cells), turning “cold” tumors into “hot” tumors.
Mian Tang, Junteng Qiu, Yunfeng Lu, Yahui Song, Xinyu Zhou, Tianshun Duan, Xuanqi Peng, Caixia Yin, Cheng Gao, Ruibing Wang   +9 more
wiley   +1 more source

Intestinal Source Control of Lipid Metabolism by Enzyme‐Probiotic Encapsulated, Spatiotemporal Crosslinked, and Small Intestine‐Adhesive Hydrogel Microspheres

Advanced Science, EarlyView.
A thiol‐modified alginate hydrogel microsphere‐encapsulated enzyme‐probiotic biohybrid (AKK‐COD) system has been developed to address the spatiotemporal delivery and colonization challenges of small intestine‐targeted probiotic for lipid metabolism regulation. The system exerts sequential functions of intragastric protection, small intestinal adhesion,
Xiaolin Wu, Weiwen Liang, Siqi He, Guangyuan Chen, Hui Zhou, Xinglong Wang, Yifei Li, Dingcai Wu, Bingna Zheng, Ruoxu Dou, Rongkang Huang   +10 more
wiley   +1 more source

A Viscous DES‐AAV‐Foxo1 Delivery System With High Transfection Efficiency for the Treatment of Corneal Endothelial Dysfunction by Restoring Mitochondria‐ER Contacts

Advanced Science, EarlyView.
High glucose triggers corneal endothelial dysfunction by impairing FOXO1‐mediated ITPR1 transcription, leading to disrupted mitochondria‐associated membrane (MAM) integrity and defective ER‐to‐mitochondria Ca2+ transfer. This study develops an innovative viscous DES‐AAV‐Foxo1 delivery system with enhanced transfection efficiency. This non‐invasive gene
Hongran Zhao, Xiaoyu Li, Hongwei Wang, Zongyi Li, Qun Wang, Yangyang Zhang, Xu Jing, Xia Qi, Qingjun Zhou, Shengqian Dou, Lixin Xie   +10 more
wiley   +1 more source