Results 41 to 50 of about 262,578 (260)

Brief images : massive pericardial effusion [PDF]

open access: yes, 2014
Significant pericardial effusions are an uncommon but very important disorder in childhood. Referring to one of the patients, cross-sectional imaging demonstrated a massive pericardial effusion. The underlying etiology here was connective tissue disease
Maharaj, Satish, Chang, Simone
core  

Ascites, pleural, and pericardial effusion in primary hypothyroidism: a rare case report

open access: yes, 2023
Hypothyroidism is caused by a deficiency of thyroid hormones and is a common endocrine disorder worldwide. It can affect nearly every organ, resulting in multiple clinical manifestations. Ascites, pleural effusion, and pericardial effusion, although less
Mogildea, Mihail   +4 more
core   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Tumor associated antigens in diagnosis of serous effusions [PDF]

open access: yes, 1988
The use of tumour associated antigens in the diagnosis of serous effusions was studied in 76 patients with benign and 200 patients with malignant disease.
Permanetter, W.   +4 more
core   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Management of Malignant Pleural Effusion (MPE) in a Tertiary Hospital in a low-income-country: Challenges and Prospects

open access: yesIbom Medical Journal, 2020
Background: In the West African sub-region, significant morbidity and mortality are known to affect patients with malignant pleural effusion (MPE) but are highly under reported unlike USA, Europe or South Africa. Aim/Objective: To review cases of MPE in
Nwafor IA   +3 more
doaj   +1 more source

THE ROLE OF N-ACETYLCYSTEINE IN THE TREATMENT OF OTITIS MEDIA WITH EFFUSION [PDF]

open access: yesBasrah Journal of Surgery, 2019
Otitis media with effusion (OME) is a chronic accumulation of fluid within the middle ear cleft and sometimes the mastoid air cells system. The disease is more common among children.
Dhiaa Fadhel   +3 more
doaj   +1 more source

Fluid Overload

open access: yesFrontiers in Veterinary Science, 2021
Fluid overload (FO) is characterized by hypervolemia, edema, or both. In clinical practice it is usually suspected when a patient shows evidence of pulmonary edema, peripheral edema, or body cavity effusion. FO may be a consequence of spontaneous disease,
Bernie Hansen
doaj   +1 more source

Prevalence of Otitis Media with Effusion in Children of Damietta Governorate (Egypt) [PDF]

open access: yesInternational Journal of Medical Arts, 2020
Background: Otitis media with effusion is a prevalent disease of pediatrics. It is usually a self-limiting disease. However, it may be complicated by serious consequences.
Mohamed Abdelazim   +2 more
doaj   +1 more source

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