Results 261 to 270 of about 785,489 (353)

Feasibility of replacing ^99mTc‐DTPA GFR measurements with eGFR from cystatin C in individuals with spinal cord injuries [PDF]

Tatiana Kristensen, Peter Oturai, Bryan Haddock, Fin Biering‐Sørensen, Christina Kruuse, Ulrik B. Andersen   +5 more
openalex   +1 more source

Identification and Mechanisms of Osteocyte Subsets Involved in the Pathological Progression of Osteoporosis

Advanced Science, EarlyView.
Osteocyte heterogeneity in bone remains poorly understood. This study identifies six distinct osteocyte subsets in mice, revealing a key subpopulation (BHR‐Ocys) that drives bone loss in osteoporosis. BHR‐Ocys promote osteoclast‐mediated resorption via a novel Sema5a‐Plxna1 signaling axis.
Zengxin Jiang, Biyu Rui, Xuecheng He, Jiajun Wang, Xiangdong Wu, Rui Shao, Xue Meng, Xiaochun Peng, Hengfeng Yuan   +8 more
wiley   +1 more source

Real-World Data: Critical Evidence to Better Understanding Kidney Benefits with Sodium-Glucose Cotransporter 2 Inhibitors. [PDF]

Kidney360
Neumiller JJ, Tuttle KR.
europepmc   +1 more source

Cancer Stem Cells Shift Metabolite Acetyl‐Coenzyme A to Abrogate the Differentiation of CD103+ T Cells

Advanced Science, EarlyView.
Lei et al. demonstrate that cancer stem cells (CSCs) play a pivotal role in impairing the differentiation of CD103+ T cells in patients with non‐small‐cell lung cancer. The key mechanism involves CSC‐derived acetyl‐CoA, which disrupts CD103+ T cell differentiation by sequentially inducing acetylation and ubiquitination of the Blimp‐1 protein. Targeting
Jiaxin Lei, Huiyan Ji, Jing Guo, Mengdi Liu, Danhua Su, Yiran Zheng, Lin Xu, Qinghua Cao, Tao Ren, Jun Gui, Zhenke Wen   +10 more
wiley   +1 more source

Novel FAK inhibitors suppress tumor growth and reverse EGFR-TKI resistance in non-small cell lung cancer. [PDF]

Cancer Drug Resist
Xu G, Pecoraro C, Vahabi M, Deng D, Cavazzoni A, Fiuji H, Lagrasta CAM, Cascioferro SM, Tiseo M, Carbone D, Avan A, Zucali PA, Assaraf YG, Peters GJ, Diana P, Giovannetti E.   +15 more
europepmc   +1 more source

Integrated ERK‐PKA‐YAP/TAZ‐SHH Signaling Orchestrates Cortical Radial Glia Identity and Lineage Diversification

Advanced Science, EarlyView.
This study shows that ERK/PKA upregulation in mammalian cortical radial glia (RGs) sustains neurogenesis and suppresses gliogenesis. YAP/TAZ activation promotes ependymal cell formation, while enhanced SHH‐SMO signaling induces astrocyte, oligodendrocytes, and olfactory bulb interneuron generation.
Zhuangzhi Zhang, Zhejun Xu, Tongye Fu, Jialin Li, Feihong Yang, Chuannan Yang, Wenhui Zheng, Zizhuo Sha, Yanjing Gao, Mengge Sun, Zhenmeiyu Li, Jing Ding, Xiaosu Li, Zhengang Yang   +13 more
wiley   +1 more source

Association of Intraindividual Difference in Cystatin C and Creatinine Estimated Glomerular Filtration Rate With Diabetes. [PDF]

J Diabetes Res
Zhang L, Yu Y, Zhao Y, Wang X.
europepmc   +1 more source

EGFR has a tumour-promoting role in liver macrophages during hepatocellular carcinoma formation

, 2014
Hanane Lanaya, Anuradha Natarajan, Karin Komposch, Liang Li, Nicole Amberg, Lei Chen, Stefanie K. Wculek, Martina Hammer, Rainer Zenz, Markus Peck‐Radosavljevic, Wolfgang Sieghart, Michael Trauner, Hongyang Wang, Maria Sibilia   +13 more
openalex   +1 more source

The power of the few [PDF]

, 2017
Chen, Ran, Gutmann, David H, Pan, Yuan
core   +2 more sources

Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy

Advanced Science, EarlyView.
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro, Yoojin Chang, Jeeyoon Kim, Seungjae Lee, Sangyun Na, Cheolhong Park, Hyunhyub Ko   +6 more
wiley   +1 more source