Results 301 to 310 of about 785,489 (353)

Effect of EGFR-TKI targeted therapy in patients with advanced non-small cell lung cancer.

, 2022
Meihao Yan, Shanshan Chen, Hongtao Fan, Yuancheng Hong, Wencheng Huang, Zhimin Lin, Zhangchao Lai, Hong Li-yue   +7 more
openalex   +1 more source

Research advancements and evaluation of multifactor‐induced murine models for gastric cancer

Animal Models and Experimental Medicine, EarlyView.
Murine models for gastric cancer. Abstract As one of the most prevalent gastrointestinal malignancies in humans, gastric cancer (GC) is often detected at an advanced stage, resulting in a poor prognosis and ranking it the fifth leading cause of cancer‐related deaths.
Yiqing Wang, Liang Zhang, Weixu Feng, Wanfeng Liu, Xiangyang Xue, Shiyu Feng   +5 more
wiley   +1 more source

One‐Step Assembly of α‐Aryl‐Substituted DOTAs as Superior and Universal Platforms for Multifunctional Theranostics

Angewandte Chemie, EarlyView.
A one‐step multi‐component synthetic approach is reported to construct α‐aryl‐substituted DOTAs, which required tedious multi‐step synthesis in all previous works. The synthesized α‐aryl‐substituted DOTAs showed improved performance for developing multifunctional theranostics and represent a universal platform for bioconjugation. Abstract α‐Substituted
Pak‐Lun Lam, Yue Wu, Lijia Yao, Hei‐Yui Kai, Ho‐Fai Chau, Qian Zhang, Wanqi Zhou, Jean‐Claude G. Bünzli, Ka‐Leung Wong   +8 more
wiley   +2 more sources

EGFR pathway alterations correlate with rapid early progression in glioblastoma. [PDF]

J Neurooncol
Samimi K, Saini AS, Cullison K, Herr J, Mellon EA.   +4 more
europepmc   +1 more source

A Novel Chimeric Antigen Receptor (CAR) - Strategy to Target EGFR^VIII-Mutated Glioblastoma Cells via Macrophages

Kristi Vera, Gülen Esken, Jin Wook Hwang, Carine Elbaz, Diana Chaker, Noufissa Oudrhiri, Christophe Desterke, Frank Griscelli, Annelise Bennaceur-Griscelli, Ali G Turhan   +9 more
openalex   +2 more sources

Approaches to Enhance Photodynamic Therapy of Lung Cancer: Potential Application of Nanoparticles

Advanced NanoBiomed Research, EarlyView.
Bioactive ligand‐targeted nanocarriers can accommodate functionalization with numerous targeting ligands for effective delivery of photosensitizers (PSs) within targeted photodynamic therapy. Various targeting moieties including peptides, antibodies, carbohydrates, aptamers, proteins, and PS anticancer molecules can be attached to nanomaterials.
Nokuphila Winifred Nompumelelo Simelane, Heidi Abrahamse   +1 more
wiley   +1 more source

Association between caffeine and the eGFR dip after initiation of SGLT2 inhibitors in adult patients. [PDF]

Physiol Rep
Kisley Z, Kalishman AJ, Memon AA, Dhindsa SS, Edwards JC, Mosman A, Lentine KL, Kunnath P, Wood E, Miyata KN.   +9 more
europepmc   +1 more source

Nanobiotechnology‐Based Approaches for Targeted Glioma Therapy

Advanced NanoBiomed Research, EarlyView.
Nanoparticle systems cross the blood–brain barrier to deliver drugs precisely to glioma cells. Lipid, polymeric, and magnetic carriers enable controlled release, tumor targeting, and microenvironment modulation. These nanoplatforms enhance chemotherapy, radiotherapy, and immunotherapy, improving therapeutic efficacy while reducing systemic toxicity ...
Jinwei Li, Yibo He, Yang Zhang, Lining Arnold Ju, Yao Wang, Jianxuan Zhou, Yinying Chai, Xuhui Hui, ShiYuan Tong, Si Zhang, Yanli Tan, Yinyan Wang   +11 more
wiley   +1 more source

EGFR gene amplification in IDH-wildtype glioblastomas: an integrative bioinformatic and histopathological analysis using immunohistochemistry and fluorescence in situ hybridization. [PDF]

Discov Oncol
Oukhdouch A, Zinbi B, Sellami S, Rais H.
europepmc   +1 more source

The Intricate Web of MicroRNAs in Modulating EGFR-TKI Resistance in Non-Small Cell Lung Cancer: A Comprehensive Review. [PDF]

Cancer Manag Res
Xu Y, Huang J.
europepmc   +1 more source