Results 291 to 300 of about 775,670 (354)

Systematic review and scoring‐based selection of pharmacokinetic models for precision dosing of vancomycin in neonates and children

British Journal of Clinical Pharmacology, EarlyView.
This systematic review identified 112 population pharmacokinetic models of vancomycin in neonates and children. To support rational model selection for model‐informed precision, we developed and applied expert‐driven, transparent criteria that integrate both methodological rigour and clinical relevance.
Zoë Vander Elst, Pieter‐Jan Spiessens, Dorian Vanneste, Nada Dia, Matthias Gijsen, Isabel Spriet, Karel Allegaert, Erwin Dreesen, Anne Smits   +8 more
wiley   +1 more source

TAD boundaries and gene activity are uncoupled. [PDF]

Elife
Almansour F, Fursova NA, Keikhosravi A, Reed KSM, Larson DR, Pegoraro G, Misteli T.   +6 more
europepmc   +1 more source

Safety Profile and Tumor Response of EGFR-TKIs in Clinical Practice: A Real-World Study in Thailand. [PDF]

J Clin Med
Jainan P, Pongsathabordee C, Sadabpod K, Junkrut T, Jerasirichot T, Phetchuensakun O, Paiboonvong T, Srithonrat S.   +7 more
europepmc   +1 more source

Cardiometabolic risk burden and kidney function in middle-aged and older adults: evidence from two national, cross-sectional studies in China and the United States. [PDF]

Ren Fail
Jiang W, Zhang F, Zhang X, Zhong Y, Chen Y.   +4 more
europepmc   +1 more source

An EGFR co-amplified lncRNA HELDR promotes glioblastoma malignancy through KAT7-driven gene programs. [PDF]

Nat Cell Biol
Yu X, Song X, Schäfer RA, Meng Q, Tiek D, Wu R, He Q, Walker M, Cao Q, Yang R, Hu B, Cheng SY.   +11 more
europepmc   +1 more source

Ferulic and <i>p</i>-coumaric acid derivatives as dual EGFR-VEGFR2 inhibitors: design, semi-synthesis, and biological investigations. [PDF]

RSC Adv
Elrayess R, Nafie MS, Ahmed SA, Alkazzaz YK, Darwish KM, Gad El-Hak HN, Eltamany EE.   +6 more
europepmc   +1 more source

Targeted therapy in the treatment of lung cancer in Iceland 2010-2023. [PDF]

Acta Oncol
Tryggvadóttir SÁ, Stefánsson GV, Birgisson H, Gunnarsson Ö, Guðbjartsson T, Harðardóttir H, Hilmarsdóttir B, Barkardóttir RB, Haraldsdottir S.   +8 more
europepmc   +1 more source