Results 11 to 20 of about 4,755 (111)

Mutations associated with egg adaptation of influenza A(H1N1)pdm09 virus in laboratory based surveillance in China, 2009–2016

Biosafety and Health, 2019
Mutations of influenza virus associated with adaptation occurring during passage in embryonated chicken eggs could result in antigenic change or reduced vaccine effectiveness.
Lei Yang, Yanhui Cheng, Xiang Zhao, Hejiang Wei, Minju Tan, Xiyan Li, Wenfei Zhu, Weijuan Huang, Wenbing Chen, Jia Liu, Zi Li, Yuelong Shu, Dayan Wang   +12 more
doaj   +1 more source

Tropism of pandemic 2009 H1N1 influenza A virus

Frontiers in Microbiology, 2012
Substitutions at the receptor binding site of the pandemic H1N1 2009 influenza A virus (H1N1pdm) hemagglutinin (HA) gene may be critical in determining whether a virus binds to human or avian receptors.
Ririn eRamadhany, Mayo eYasugi, Shota eNakamura, Shota eNakamura, Tomo eDaidoji, Tomo eDaidoji, Yohei eWatanabe, Kazuo eTakahashi, Kazuyoshi eIkuta, Takaaki eNakaya, Takaaki eNakaya, Takaaki eNakaya   +11 more
doaj   +1 more source

Evolution of H9N2 avian influenza virus in embryonated chicken eggs with or without homologous vaccine antibodies

BMC Veterinary Research, 2018
Background Vaccines constitute a unique selective pressure, different from natural selection, drives the evolution of influenza virus. In this study, A/Chicken/Shanghai/F/1998 (H9N2) was continually passaged in specific pathogen-free embryonated chicken ...
Haiyun Jin, Wan Wang, Xueqin Yang, Hailong Su, Jiawen Fan, Rui Zhu, Shifeng Wang, Huoying Shi, Xiufan Liu   +8 more
doaj   +1 more source

A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine.

PLoS Pathogens, 2017
The effectiveness of the annual influenza vaccine has declined in recent years, especially for the H3N2 component, and is a concern for global public health.
Nicholas C Wu, Seth J Zost, Andrew J Thompson, David Oyen, Corwin M Nycholat, Ryan McBride, James C Paulson, Scott E Hensley, Ian A Wilson   +8 more
doaj   +1 more source

Attenuation of Bluetongue Virus (BTV) in an in ovo Model Is Related to the Changes of Viral Genetic Diversity of Cell-Culture Passaged BTV

Viruses, 2019
The embryonated chicken egg (ECE) is routinely used for the laboratory isolation and adaptation of Bluetongue virus (BTV) in vitro. However, its utility as an alternate animal model has not been fully explored.
Fabian Z. X. Lean, Matthew J. Neave, John R. White, Jean Payne, Teresa Eastwood, Jemma Bergfeld, Antonio Di Rubbo, Vittoria Stevens, Kelly R. Davies, Joanne Devlin, David T. Williams, John Bingham   +11 more
doaj   +1 more source

In vivo passage of Salmonella Typhimurium results in minor mutations in the bacterial genome and increases in vitro invasiveness

Veterinary Research, 2019
Eggs and raw or undercooked egg-containing food items are frequently identified as the bacterial source during epidemiolocal investigation of Salmonella outbreaks.
Andrea R. McWhorter, Rick Tearle, Talia S. Moyle, Kapil K. Chousalkar   +3 more
doaj   +1 more source

Digestion of copepod eggs by larval turbot Scophthalmus maximus and egg viability following gut passage

Marine Ecology Progress Series, 1994
Between 20.5 and 93.6 % of the subitaneous eggs of 6 species of egg-carrying copepods passed undigested through the digestive tracts of larval and early postlarval turbot Scophthalmus maximus. Viability of the eggs of Eurytemora affinis, E. velox and Euterpina acutifrons remained high on egestion (67.0 to 91.7 %), Pseudocalanus elongatus and Oncaea ...
DVP Conway, IRB McFadzen, PRG Tranter
openaire   +1 more source

Comparison of antigenic mutation during egg and cell passage cultivation of H3N2 influenza virus [PDF]

Clinical and Experimental Vaccine Research, 2020
When influenza viruses are cultured in eggs, amino acid mutations of the hemagglutinin may occur through egg adaptation. On the other hand, when influenza viruses are cultured in animal cells, no antigenic mutation occurs unlike in eggs. Therefore, we examined whether the antigenic mutations actually occurred after passage of H3N2 (A/Texas/50/2012 ...
Yong Wook Park, Yun Hee Kim, Hwan Ui Jung, Oh Seok Jeong, Eun Ji Hong, Hun Kim, Jae Il Lee   +6 more
openaire   +2 more sources

Scientific Opinion on bluetongue serotype 8

EFSA Journal, 2011
To answer a question from the European Commission on the potential special characteristics of bluetongue virus (BTV) serotype 8 (BTV‐8) compared to other serotypes and their possible impact on the epidemiology of the disease, a systematic literature ...
EFSA Panel on Animal Health and Welfare
doaj   +1 more source

Changes in the virulence ofMycobacterium aviumafter passage through embryonated hens’ eggs [PDF]

FEMS Microbiology Letters, 2000
Eight-day-old embryonated hen's eggs were used as a model to study Mycobacterium avium virulence. Strains isolated from human patients caused 20-90% mortality when eggs were infected by injection of bacterial suspensions into the amniotic sac. Virulence of examined strains subsequently decreased with passage through eggs to between 0 and 40% mortality ...
E G, Long, E P, Ewing, J H, Bartlett, C R, Horsburgh, K A, Birkness, M A, Yakrus, G W, Newman, F D, Quinn   +7 more
openaire   +3 more sources