Direct regulation of Treslin by cyclin-dependent kinase is essential for the onset of DNA replication [PDF]
Treslin, a TopBP1-interacting protein, is necessary for deoxyribonucleic acid (DNA) replication in vertebrates. Association between Treslin and TopBP1 requires cyclin-dependent kinase (Cdk) activity in Xenopus laevis egg extracts.
Dunphy, William G.+3 more
core +2 more sources
Supervariate Gel Transforms into Various Biominerals in Salt Solutions
It is revealed that common calcium‐based biominerals can form from a stable, non‐toxic ‘supervariate’ gel. This tunable gel selectively yields calcite or hydroxyapatite in carbonate/phosphate solutions, while CaCl₂ facilitates the formation of dihydrate calcium pyrophosphate, which converts to hydroxyapatite upon drying. These findings provide insights
Xinxue Tang+12 more
wiley +1 more source
The molecular chaperone Hsp90 is a component of the cap-binding complex and interacts with the translational repressor Cup during Drosophila oogenesis [PDF]
In metazoa, the spatio-temporal translation of diverse mRNAs is essential to guarantee proper oocyte maturation and early embryogenesis. The eukaryotic translation initiation factor 4E (eIF4E), which binds the 5′ cap structure of eukaryotic mRNAs ...
COZZOLINO M.+10 more
core +1 more source
Distribution of Mercury and Selenium in Egg Components and Egg-White Proteins
Methylmercuric chloride (Hg) at 20 ppM and sodium selenite (Se) at 8 ppM were fed, separately and in combination, to laying hens. Oral doses of CH/sub 3//sup 203/HgCl and H/sub 2//sup 75/SeO/sub 3/ also were given to all hens. The concentration of /sup 203/Hg and /sup 75/Se in egg white and egg yolk, and the distribution of the radioisotopes among ...
Welsonia J. Magat, Jerry L. Sell
openaire +3 more sources
An RBC membrane camouflaged, cell‐penetrating peptides R8‐based drug delivery system is constructed to achieve a synergistic combination of natural compounds triptolide (TP) and celastrol (Cel), inducing tumor cell apoptosis, reducing tumor metastasis invasion and triggering autophagy disorder in breast cancer and liver cancer.
Qian Cheng+6 more
wiley +1 more source
A Mutant \u3cem\u3edec-1\u3c/em\u3e Transgene Induces Dominant Female Sterility in \u3cem\u3eDrosophila melanogaster\u3c/em\u3e [PDF]
The Drosophila dec-1 gene produces three proproteins required for female fertility and eggshell assembly. The three proproteins are distinguished by their C termini.
Spangenberg, Daniel K., Waring, Gail L.
core +1 more source
Reducing Campylobacter jejuni colonization in broiler chickens by in-feed supplementation with hyperimmune egg yolk antibodies [PDF]
Campylobacter infections sourced mainly to poultry products, are the most important bacterial foodborne zoonoses worldwide. No effective measures to control these infections in broiler production exist to date.
Canessa, Stefano+8 more
core +1 more source
Cardiac Organoid Model Inspired Micro‐Robot Smart Patch to Treat Myocardial Infarction
The heart organoid model exhibits the acidic microenvironment characteristic of myocardial infarction, which emerges as a pivotal force propelling the movement of micro‐robots. These micro‐robots, administered through microneedles, can penetrate deep into the tissue, effectively delivering therapeutic payloads to facilitate heart repair.
Fangfang Wang+12 more
wiley +1 more source
Brownian Dynamics Simulations of Proteins in the Presence of Surfaces: Long-range Electrostatics and Mean-field Hydrodynamics [PDF]
Simulations of macromolecular diffusion and adsorption in confined environments can offer valuable mechanistic insights into numerous biophysical processes. In order to model solutes at atomic detail on relevant time scales, Brownian Dynamics simulations can be carried out with the approximation of rigid body solutes moving through a continuum solvent.
arxiv
COMPUSI BIOCHIMICI COMPLECSI CU POTENTIAL BIOTEHNOLOGIC DIN ALBUSUL OAULOR DE GAINA
Eggs are natural foods with high nutritional benefits providing an inexpensive and low calorie source of high quality protein and several important nutrients.
Felicia Boar, V. Miclea, H. Banciu
doaj +1 more source