Results 111 to 120 of about 289,071 (336)
Advanced Science, EarlyView.The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang +15 more
wiley +1 more source
Scientific and technological challenges of recombinant egg protein production
BMC BiotechnologyEggs are among the most widely consumed and versatile animal-derived foods and are valued for their exceptional nutritional and functional properties. However, conventional egg production is associated with significant environmental, ethical, and health ...
Franziska Beck +3 more
doaj +1 more source
Advanced Science, EarlyView.Genome‐wide, high‐resolution profiling of hydroxymethylation in mouse SCNT embryos reveals a transient, allele‐symmetric 5hmC reprogramming pattern distinct from natural embryos, with X‐chromosomes and imprinting control regions resistant to proper remodeling.
Zeming Xiang +9 more
wiley +1 more source
Photoaffinity Labeling of High Affinity Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP)-Binding Proteins in Sea Urchin Egg [PDF]
, 2011 Timothy F. Walseth +7 more
openalex +1 more source
Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth
Advanced Science, EarlyView.Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang +12 more
wiley +1 more source
Effect of immunized egg proteins on the performance and neonatal diarrhoea incidence in newborn calves. [PDF]
J Anim Physiol Anim Nutr (Berl), 2021 van Kuijk S +5 more
europepmc +1 more source
Effect of Dietary Crude Protein Levels on Egg Production, Hatchability and Post-Hatch Offspring Performance of Indigenous Chickens [PDF]
, 2010 AM King’ori +3 more
openalex +1 more source
Performance of Egg Laying Japanese Quail Hens Fed Low Protein Diet Supplemented with Protease and/or Formic Acid [PDF]
, 2022 Nada Mostafa Eltafahny +3 more
openalex +1 more source
Advanced Science, EarlyView.This study reveals that the E3 ubiquitin ligase TRIM56 exacerbates neuronal ferroptosis and brain damage by mediating K48‐linked ubiquitination and degradation of KLF4, leading to suppression of the xCT/GSH/GPX4 axis. Targeting TRIM56 alleviates cerebral ischemia‐reperfusion injury in vivo and in vitro, highlighting its therapeutic potential.
Qiangping Wang +15 more
wiley +1 more source