Results 101 to 110 of about 102,605 (303)

Filhos da mãe - Animus da mãe na vida do filho

Self, 2019
Este artigo tem por objetivo refletir sobre as pessoas nascidas no contexto da ausência paterna, os “filhos da mãe”. A partir do entendimento do inestimável valor do fenômeno relacional humano e do funcionamento psíquico, este trabalho aplica os ...
Irene Pereira Gaeta
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Ego-net analysis in educational contexts

, 2019
This dataset illustrates an approach to conducting ego-net analysis in education. The data are provided by Dr. Christoforos Mamas, Ms. Giovanna Shaelli, and Dr. Alan J.
Mamas, Christoforos, Daly, Alan, Hartmann Schaelli, Giovanna   +2 more
core   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Freudian Psychoanalytic Exploration of Will Freeman's Transformation into an Impromptu Parent in Nick Hornby's 'About a Boy'

Journal of English Language Teaching and Literature
Through the lens of Sigmund Freud's psychoanalytic theory—specifically, the id, ego, and superego this study examines the psychological development of Will Freeman, the main character in Nick Hornby's novel About a Boy.
Muhammad Pasha Nabih Nurdin, Zuhrul Anam
doaj   +1 more source

Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up

Molecular Oncology, EarlyView.
This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani, Laura Mariën, Caro De Weerdt, Sanne Wouters, Laure‐Anne Teuwen, Hans Prenen, Katleen Janssens, Timon Vandamme   +7 more
wiley   +1 more source

Formacija »Super ego« i savjest [PDF]

, 1969
Psychicus modus reagendi, nuncupatus «Super — Ego« unus est ex septem hucusque a psychologis inventis modis qui sunt: Automaticus modus, Primitivus (Es, Ca), Persona (masque), Umbra (Schatten, Ombre), Ego (Ich, Moi), Super-ego (Ober-ich, Surmoi), Ipsum ...
Weissgerber, Josip
core   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Neural network modeling of psychoanalytic concepts

Frontiers in Systems Neuroscience
Techniques used over decades in brain-based neural network modeling are applied to understanding processes involved in psychoanalysis. Behavioral change is interpreted as a transition, using simulated annealing, from a less to a more optimal attractor in
Daniel S. Levine, Ana Maria C. Aleksandrowicz, Ana Luiza S. Verissimo Lopes   +2 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source