Results 121 to 130 of about 675,397 (326)

Freudian Psychoanalytic Exploration of Will Freeman's Transformation into an Impromptu Parent in Nick Hornby's 'About a Boy'

open access: yesJournal of English Language Teaching and Literature
Through the lens of Sigmund Freud's psychoanalytic theory—specifically, the id, ego, and superego this study examines the psychological development of Will Freeman, the main character in Nick Hornby's novel About a Boy.
Muhammad Pasha Nabih Nurdin, Zuhrul Anam
doaj   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

A MORALIDADE DA GLOBALIZAÇÃO

open access: yesRevista Latinoamericana de Bioética, 2010
El artículo reflexiona sobre el proceso de la globalización y los impactos del consumo en las sociedades contemporáneas, estableciendo relación entre este fenómeno y los procesos culturales y sociales de la construcción de la identidad así como respecto ...
DORA PORTO
doaj  

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

open access: yesAging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath   +3 more
wiley   +1 more source

Fragile egos [PDF]

open access: yesNature Clinical Practice Gastroenterology & Hepatology, 2007
openaire   +2 more sources

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

open access: yesAging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Deterioro de la creación científica en el ámbito educativo: una perspectiva evolucionista

open access: yesRevista Complutense de Educación, 2003
Este articulo trata de la incidencia de los circulos autocompllacientes de investigacion en la calidad de la investigacion cientifica. La tesis central es que este fenomeno, especialmente caracteristico en educacion, lastra y sesga el conocimiento ...
AGUSTÍN DE LA Herrán Gascón
doaj  

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