Results 71 to 80 of about 656,973 (277)
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Automatic surrogate model type selection during the optimization of expensive black-box problems [PDF]
, 2011 The use of Surrogate Based Optimization (SBO) has become commonplace for optimizing expensive black-box simulation codes. A popular SBO method is the Efficient Global Optimization (EGO) approach. However, the performance of SBO methods critically depends
Couckuyt, Ivo +3 more
core +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Psychologia a buddyzm. Czego psycholodzy mogą się nauczyć od buddystów a buddyści od psychologów?
Podstawy Edukacji, 2016 Artykuł przedstawia stanowiska psychologów, buddystów oraz psychologów-buddystów w kwestii podobieństw i różnic między metodami psychologii zachodniej i buddyzmu.
Jacek Sieradzan
doaj +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
La dificultad de llegar a acuerdos en las relaciones humanas: del control del ego a la paz interior
INFAD, 2014 Querer tener razón es la principal causa de los conflictos que afectan a las relaciones interpersonales. Y la razón de ser de dicha causa la encontramos en el Ego. (Vamos a utilizar el término Ego, como la parte del Yo que se pone al servicio del superyo,
Isaac Encinas Martín +1 more
doaj +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Self, 2019 Este trabalho trata-se de um estudo de caso, com duração de quatro anos, em sessões semanais de 50 minutos, realizadas em consultório particular. Foram utilizados o recurso das técnicas expressivas e a análise de sonhos.
Clara Rossana Ferraro de Sá
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Egomunities, Exploring Socially Cohesive Person-based Communities [PDF]
, 2011 In the last few years, there has been a great interest in detecting overlapping communities in complex networks, which is understood as dense groups of nodes featuring a low outbound density.
Chelius, Guillaume +2 more
core +4 more sources