Results 21 to 30 of about 8,274 (166)

HES and EGPA: Two Sides of the Same Coin.

, 2023
Elevated eosinophil counts are implicated in multiple diseases, from relatively prevalent organ-specific disorders such as severe eosinophilic asthma, to rare multisystem disorders such as hypereosinophilic syndrome (HES) and eosinophilic granulomatosis ...
Akuthota, Praveen, Kwon, Namhee, Steinfeld, Jonathan, Roufosse, Florence, Khoury, Paneez   +4 more
core   +1 more source

A Retrospective Review of 1821 Cases of Eosinophilia in a Single-Center Study in Eastern China. [PDF]

EJHaem
ABSTRACT Objective: Our study aims to explore the types of diseases that may cause eosinophilia and the changes in the disease spectrum of different degrees of eosinophilia. Methods We retrospectively analyzed patients who were admitted to the First Affiliated Hospital of Soochow University from July 1, 2023 to June 30, 2024, and had at least twice ...
Ma Y, Wang L, Cheng Y, Yang X, Chen S.
europepmc   +2 more sources

Update on eosinophilic granulomatosis with polyangiitis

Allergology International, 2019
Eosinophilic granulomatosis with polyangiitis (EGPA) (formerly Churg-Strauss syndrome) is a rare form of anti-neutrophil cytoplasm antibody (ANCA)-associated vasculitis characterized by eosinophil-rich granulomatous inflammation and small to medium-size ...
Shunsuke Furuta, Taro Iwamoto, Hiroshi Nakajima   +2 more
doaj   +1 more source

Targeting the interleukin-5 pathway in EGPA: Evidence, uncertainties and opportunities

, 2022
Only a minority of patients with eosinophilic granulomatosis with polyangiitis (EGPA) can be weaned-off glucocorticoids (GC) using conventional treatment strategies.
Vaglio A., Del Giacco S., Berti A., Atzeni F., Salvarani C., Emmi G., Dagna L.   +6 more
core   +2 more sources

Benralizumab monotherapy was insufficient to induce remission in patients with active eosinophilic granulomatosis with polyangiitis

Respiratory Medicine Case Reports, 2022
Eosinophils play an important pathogenetic role in the development of eosinophilic granulomatosis with polyangiitis (EGPA). EGPA has long been treated with systemic corticosteroids and immunosuppressive agents.
Osamu Matsuno, Seijiro Minamoto
doaj   +1 more source

Insights from Social Media on the Patient Experience of Living With Rare Eosinophil-Driven Diseases

Journal of Patient Experience, 2022
Eosinophilic granulomatosis with polyangiitis (EGPA) and hypereosinophilic syndrome (HES) are driven by persistently high eosinophil numbers, causing damage to tissues and organs.
Mary Jo Strobel, Debbie Alves MA, Florence Roufosse MD, PhD, Zeina Antoun MD, Namhee Kwon MD, Lee Baylis MD, Michael E Wechsler MD, MMSc   +6 more
doaj   +1 more source

The Diagnostic Challenge of Eosinophilic Granulomatosis With Polyangiitis Presenting as Acute Eosinophilic Myocarditis: Case Report and Literature Review

Frontiers in Cardiovascular Medicine, 2022
Eosinophilic granulomatosis with polyangiitis (EGPA) is a systemic vasculitis involving small-to-medium-sized vessels characterized by asthma, vasculitis, and peripheral eosinophilia.
Hiroyuki Yamamoto, Katsuya Hashimoto, Yoshihiko Ikeda, Jun Isogai, Toru Hashimoto   +4 more
doaj   +1 more source

New perspectives in eosinophilic granulomatosis with polyangiitis (EGPA): report of the first meeting of the European EGPA Study Group.

, 2020
The European Eosinophilic Granulomatosis with Polyangiitis (EGPA) study group first gathered in Firenze in December 2018. The discussion was centred around the clinical and therapeutic needs in EGPA which still remain unmet.

core   +2 more sources

Pinhole-Like Central Bronchial Narrowing: A Rare Reversible Manifestation of Eosinophilic Bronchial Inflammation. [PDF]

Respirol Case Rep
Eosinophilic bronchial inflammation can cause severe central bronchial narrowing and recurrent atelectasis, even in patients with well‐controlled asthma. Endobronchial biopsy can establish the diagnosis and identify this potentially reversible, corticosteroid‐responsive condition.
Kizawa R, Saito Z, Minekawa K, Takatsuka M, Kitayama T, Yoshida M, Numata T, Araya J.   +7 more
europepmc   +2 more sources

Eosinophilic granulomatosis with polyangiitis across the eosinophilic spectrum: from molecular mechanisms to practical differential diagnosis and targeted therapy

Rheumatology
Introduction Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis defined by asthma, hypereosinophilia, and multiorgan involvement.
Aleksandra Hus, Małgorzata Wisłowska
doaj   +1 more source