Results 161 to 170 of about 111,930 (282)

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

Plasmodium falciparum impairs Ang-1 secretion by pericytes in a 3D brain microvessel model. [PDF]

EMBO Mol Med
Long RKM, Korbmacher F, Ronchi P, Fleckenstein H, Schorb M, Mirza W, Mallorquí M, Aguilar R, Moncunill G, Schwab Y, Bernabeu M.   +10 more
europepmc   +1 more source

Technical qualifications for 14 to 16 year olds : 2023 key stage 4 performance tables : process for submitting qualifications : for awarding organisations, March 2020 [PDF]

, 2020

core  

Egress-related osmiophilic bodies

, 2014
© 2014 John Wiley & Sons Ltd. Summary: Gametogenesis is the earliest event after uptake of malaria parasites by the mosquito vector, with a decisive impact on colonization of the mosquito midgut. This process is triggered by a drop in temperature and contact with mosquito molecules.
Anna Olivieri, Federica Fratini, Elena Deligianni, Tomasino Pace, Blandine Franke-Fayard, Fabiana Superti, Inga Siden-Kiamos, Chris J. Janse, Chiara Currà, Lucia Bertuccini, Eric Hanssen, Marta Ponzi, Felicia Grasso   +12 more
openaire   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

First-generation merozoites of caprine <i>Eimeria christenseni</i> are capable to invade and egress primary host endothelial cells <i>in vitro</i>. [PDF]

Front Vet Sci
Silva LMR, Ruiz A, Barba E, Lopéz-Osorio S, Molina JA, Molina JM, Taubert A, Hermosilla C.   +7 more
europepmc   +1 more source

A Verandah-Trap Hut for Studying the House-Frequenting Habits of Mosquitos and for Assessing Insecticides:The Effect of Dichlorvos(DDVP) on Egress and Mortality of Anopheles Gambiae Giles and Mansonia Uniformis (THEO.) Entering Naturaly [PDF]

, 1964
Smith, Alec
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

HSV-1 US3: A Master Mimic Hijacking Host Kinase Networks for Viral Dominance. [PDF]

J Med Virol
Hossain I, Nelson CJ, Dutta O, Mohan H, Hasan M, Kousoulas KG.   +5 more
europepmc   +1 more source

A Verandah-Trap Hut for Studying the House-Frequenting Habits of Mosquitos and for Assessing Insecticides. I. A Description of the Verandah-Trap Hut and of Studies on the Egress of Anopheles Gambiae Giles and Mansonia Uniformis (Theo.) from an Untreated hut. [PDF]

, 1965
Smith, A
core   +1 more source