Results 51 to 60 of about 357 (108)

Rousette Bat Dendritic Cells Overcome Marburg Virus-Mediated Antiviral Responses by Upregulation of Interferon-Related Genes While Downregulating Proinflammatory Disease Mediators

open access: yesmSphere, 2019
Dysregulated and maladaptive immune responses are at the forefront of human diseases caused by infection with zoonotic viral hemorrhagic fever viruses. Elucidating mechanisms of how the natural animal reservoirs of these viruses coexist with these agents
Joseph Prescott   +11 more
doaj   +1 more source

Human activities link fruit bat presence to Ebola virus disease outbreaks

open access: yesMammal Review, Volume 50, Issue 1, Page 1-10, January 2020., 2020
Forest loss and fragmentation and outbreaks of Ebola virus disease (EVD) in humans are linked. Deforestation may alter the natural circulation of viruses and change the composition, abundance, behaviour and possibly viral exposure of reservoir species. This in turn might increase contact between infected animals and humans.
Jesús Olivero   +7 more
wiley   +1 more source

Thermoregulation by captive and free-ranging Egyptian rousette bats (Rousettus aegyptiacus) in South Africa [PDF]

open access: yesJournal of Mammalogy, 2017
(Uploaded by Plazi for the Bat Literature Project) Many bats, including some small-bodied tropical and subtropical Pteropodidae, use torpor to offset energetic constraints. We tested the hypothesis that medium-sized (110–160 g) cave-roosting Egyptian rousette bats (Rousettus aegyptiacus) at the southern extent of their range are able to employ torpor ...
Barclay, Robert M.R.   +7 more
openaire   +3 more sources

Antibody Responses to Marburg Virus in Egyptian Rousette Bats and Their Role in Protection against Infection [PDF]

open access: yesViruses, 2018
Egyptian rousette bats (ERBs) are reservoir hosts for the Marburg virus (MARV). The immune dynamics and responses to MARV infection in ERBs are poorly understood, and limited information exists on the role of antibodies in protection of ERBs against MARV infection.
Nadia Storm   +3 more
openaire   +3 more sources

Natural reservoir Rousettus aegyptiacus bat host model of orthonairovirus infection identifies potential zoonotic spillover mechanisms

open access: yesScientific Reports, 2022
The human-pathogenic Kasokero virus (KASV; genus Orthonairovirus) has been isolated from the sera of Egyptian rousette bats (ERBs; Rousettus aegyptiacus) captured in Uganda and unengorged Ornithodoros (Reticulinasus) faini ticks collected from the rock ...
Amy J. Schuh   +6 more
doaj   +1 more source

Development of a reverse genetics system for Sosuga virus allows rapid screening of antiviral compounds. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2018
Sosuga virus (SOSV) is a recently discovered zoonotic paramyxovirus isolated from a single human case in 2012; it has been ecologically and epidemiologically associated with transmission by the Egyptian rousette bat (Rousettus aegyptiacus).
Stephen R Welch   +7 more
doaj   +1 more source

Paramyxo- and Coronaviruses in Rwandan Bats

open access: yesTropical Medicine and Infectious Disease, 2019
A high diversity of corona- and paramyxoviruses have been detected in different bat species at study sites worldwide, including Africa, however no biosurveillance studies from Rwanda have been reported.
Wanda Markotter   +9 more
doaj   +1 more source

Marburg and Kasokero viruses elicit differential antiviral innate immune control by their natural reservoir bat, the Egyptian rousette (Rousettus aegyptiacus)

open access: hybridAntiviral Research
Shannon G. M. Kirejczyk   +9 more
openalex   +2 more sources

Assessment of listing and categorisation of animal diseases within the framework of the Animal Health Law (Regulation (EU) No 2016/429): Ebola virus disease

open access: yesEFSA Journal, Volume 15, Issue 7, July 2017., 2017
Abstract Ebola virus disease has been assessed according to the criteria of the Animal Health Law (AHL), in particular criteria of Article 7 on disease profile and impacts, Article 5 on the eligibility of Ebola virus disease to be listed, Article 9 for the categorisation of Ebola virus disease according to disease prevention and control rules as in ...
EFSA Panel on Animal Health and Welfare (AHAW)   +26 more
wiley   +1 more source

Interferon Alpha Characterization and Its Comparative Expression in PBM Cells of Capra hircus and Antelope cervicapra Cultured in the Presence of TLR9 Agonist

open access: yesMolecular Biology International, Volume 2010, Issue 1, 2010., 2010
TLR9 plays pivotal role in innate immune responses through upregulation of costimulatory molecules and induction of proinflammatory cytokines like type I interferons including interferon alpha (IFNA). The present study characterized IFNA cDNA and predicted protein sequences in goat and black buck. Response of the PBM cells to TLR9 agonist CpG ODN C and
Ramesh Doreswamy   +7 more
wiley   +1 more source

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