Results 131 to 140 of about 16,001 (150)

Association of the Heme-Controlled eIF-2α Kinase with Spectrin-Derived Peptides

1987
Translational control of mammalian protein synthesis frequently occurs at the level of peptide initiation. One control system in particular has been intensively studied during the last decade. It involves phosphorylation and dephosphorylation of the smallest subunit (α-subunit) of initiation factor 2, eIF-2.
G, Kramer, W, Kudlicki, S, Fullilove, B, Hardesty   +3 more
openaire   +2 more sources

Rat Liver pp49, a Protein That Forms Complexes with Protein Kinase CK2, Is Composed of the β and the γ Subunits of Translation Initiation Factor eIF-2

Biochemical and Biophysical Research Communications, 1996
Comparison of the amino acid sequences of two peptides derived from proteolysis of rat liver pp49 identified it as composed of the beta-subunit and the gamma-subunit of eukaryotic initiation factor-2 (eIF-2). Partial purification of rat liver eIF-2 showed that its trimeric form (alpha beta gamma) co-eluted with protein kinase CK2.
C, Gil, M, Plana, M, Riera, E, Itarte
openaire   +2 more sources

elF-2 kinases: regulators of general and gene-specific translation initiation

Trends in Biochemical Sciences, 1994
Phosphorylation of eukaryotic initiation factor-2 (eIF-2) is an important mechanism regulating general translation initiation. Two mammalian eIF-2 kinases, the double-stranded-RNA-dependent kinase (PKR) and heme-regulated inhibitor kinase (HRI), have been characterized by sequencing, revealing shared sequence and structural features distinct from other
openaire   +2 more sources

Regulation of eukaryotic protein synthesis by protein kinases that phosphorylate initiation factor eIF-2: Further evidence for a common mechanism of inhibition of protein synthesis

Biochemical and Biophysical Research Communications, 1982
Abstract The role of reversing factor (RF) in the regulation of protein synthesis by inhibitory protein kinases that phosphorylate the 38,000-dalton subunit of initiation factor eIF-2 has been examined. Results show that as with the heme-regulated protein kinase (HRI), RF restores protein synthesis in reticulocyte lysates inhibited by translational ...
openaire   +2 more sources

Eimeria tenella Translation Initiation Factor eIF-5A That Interacts With Calcium-Dependent Protein Kinase 4 Is Involved in Host Cell Invasion

Frontiers in Cellular and Infection Microbiology, 2021
Shunhai Zhu, Qiping Zhao
exaly  

Regulation of eukaryotic protein synthesis by protein kinases that phosphorylate initiation factor eIF-2

Molecular Biology Reports, 1994
openaire   +2 more sources

A novel approach to the isolation of rabbit reticulocyte haem-controlled eIF-2α protein kinase

Biochimica Et Biophysica Acta Gene Regulatory Mechanisms, 1985
Tim Hunt, R J Jackson
exaly  

Phosphorylation of the p220 subunit of eIF-4F by cAMP dependent protein kinase and protein kinase C in vitro

Biochemical and Biophysical Research Communications, 1988
Curt H Hagedorn, R D Abramson, C H Hagedorn   +2 more
exaly  

Phospholipid-sensitive Ca2+ -dependent protein kinase phosphorylates the β subunit of eukaryotic initiation factor 2 (eIF-2)

FEBS Letters, 1983
William C Merrick, J F Kuo, R C Schatzman   +2 more
exaly  

Characterization of double-stranded-RNA-activated kinase that phosphorylates   subunit of eukaryotic initiation factor 2 (eIF-2 ) in reticulocyte lysates

Proceedings of the National Academy of Sciences of the United States of America, 1980
D H Levin, I M London, R Petryshyn
exaly