Results 61 to 70 of about 720,720 (308)

Advanced Experiment Design Strategies for Drug Development

open access: yesAdvanced Intelligent Discovery, EarlyView.
Wang et al. analyze 592 drug development studies published between 2020 and 2024 that applied design of experiments methodologies. The review surveys both classical and emerging approaches—including Bayesian optimization and active learning—and identifies a critical gap between advanced experimental strategies and their practical adoption in ...
Fanjin Wang   +3 more
wiley   +1 more source

Axiom System and Completeness Expression for Quantum Mechanics [PDF]

open access: yes, 2007
The standard axiomatization of quantum mechanics (QM) is not fully explicit about the role of the time-parameter. Especially, the time reference within the probability algorithm (the Born Rule, BR) is unclear.
Held, Carsten
core   +2 more sources

A Unifying Approach to Self‐Organizing Systems Interacting via Conservation Laws

open access: yesAdvanced Intelligent Discovery, EarlyView.
The article develops a unified way to model and analyze self‐organizing systems whose interactions are constrained by conservation laws. It represents physical/biological/engineered networks as graphs and builds projection operators (from incidence/cycle structure) that enforce those constraints and decompose network variables into constrained versus ...
F. Barrows   +7 more
wiley   +1 more source

Dynamic Models of Appraisal Networks Explaining Collective Learning

open access: yes, 2016
This paper proposes models of learning process in teams of individuals who collectively execute a sequence of tasks and whose actions are determined by individual skill levels and networks of interpersonal appraisals and influence.
Bullo, Francesco   +4 more
core   +1 more source

Signature of the Simplicial Supermetric [PDF]

open access: yes, 1996
We investigate the signature of the Lund-Regge metric on spaces of simplicial three-geometries which are important in some formulations of quantum gravity. Tetrahedra can be joined together to make a three-dimensional piecewise linear manifold.
Bromley B   +17 more
core   +3 more sources

Simultaneous Triangularization of Switching Linear Systems: Arbitrary Eigenvalue Assignment and Genericity

open access: yesIEEE Transactions on Automatic Control, 2016
A sufficient condition for the stability of arbitrary switching linear systems (SLSs) without control inputs is that the individual subsystems are stable and their evolution matrices are simultaneously triangularizable (ST). This sufficient condition for
H. Haimovich
semanticscholar   +1 more source

Interpretability and Representability of Commutative Algebra, Algebraic Topology, and Topological Spectral Theory for Real‐World Data

open access: yesAdvanced Intelligent Discovery, EarlyView.
This article investigates how persistent homology, persistent Laplacians, and persistent commutative algebra reveal complementary geometric, topological, and algebraic invariants or signatures of real‐world data. By analyzing shapes, synthetic complexes, fullerenes, and biomolecules, the article shows how these mathematical frameworks enhance ...
Yiming Ren, Guo‐Wei Wei
wiley   +1 more source

Infinite eigenvalue assignment for singular systems

open access: yesLinear Algebra and its Applications, 1999
The infinite eigenvalue assignment problem for singular systems described by \[ E\dot x= Ax+ Bu,\quad E, A\in\mathbb{R}^{n\times n},\quad B\in\mathbb{R}^{n\times m},\quad \text{det }E= 0\tag{1} \] is studied. Necessary and sufficient conditions are established for the existence of a state feedback for (1) such that the closed-loop system is regular and
Chu, D., Ho, D.W.C.
openaire   +1 more source

DeepMapper: Attention‐Based AutoEncoder for System Identification in Wound Healing and Stage Prediction

open access: yesAdvanced Intelligent Discovery, EarlyView.
The authors develop a deep learning model for real‐time tracking of wound progression. The deep learning framework maps the nonlinear evolution of a time series of images to a latent space, where they learn a linear representation of the dynamics. The linear model is interpretable and suitable for applications in feedback control.
Fan Lu   +11 more
wiley   +1 more source

A multiple-choice knapsack based algorithm for CDMA downlink rate differentiation under uplink coverage restrictions [PDF]

open access: yes, 2004
This paper presents an analytical model for downlink rate allocation in Code Division Multiple Access (CDMA) mobile networks. By discretizing the coverage area into small segments, the transmit power requirements are characterized via a matrix ...
Boucherie, R.J.   +2 more
core   +1 more source

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