Results 161 to 170 of about 741,369 (310)

A Robust Serum Proteomic Signature of the E2 Allele of Apolipoprotein E

open access: yesAdvanced Science, EarlyView.
This study expands a serum protein signature of the e2 allele of APOE using multiple proteomic platforms and UK Biobank replication. The signature supports the role of APOE in lipid regulation through apolipoproteins and inflammation and includes, among others, neutrophil secreted granule proteins CAMP, CTSG, DEFA3, and MPO that point to inhibition of ...
Paola Sebastiani   +20 more
wiley   +1 more source

Author Correction: Brain tumors induce widespread disruption of calvarial bone and alteration of skull marrow immune landscape. [PDF]

open access: yesNat Neurosci
Dubey A   +27 more
europepmc   +1 more source

MSC Membrane‐Coated circPROSC‐siRNA Nanoparticles for Ameliorating Craniosynostosis by Inhibiting Premature Suture Ossification

open access: yesAdvanced Science, EarlyView.
CircPROSC promotes craniosynostosis by sponging miR‐6815‐5p, thereby activating WNT3A/β‐catenin signaling and enhancing RUNX2‐mediated osteogenesis. Targeted silencing of circPROSC with MSC membrane–coated siRNA nanoparticles (MM@Lipo/si‐circPROSC) delivered postnatally into cranial sutures attenuates premature suture closure in Twist1+/– mice ...
Zhenkun Weng   +6 more
wiley   +1 more source

Dual‐Laser Optical Tweezers for Photothermal Analysis of Hybrid Microgels

open access: yesAdvanced Science, EarlyView.
Dual‐laser optical tweezers unlock real‐time, single‐particle resolution of light‐driven actuation. Direct visualization and precise quantification of size changes under varying laser intensity provide new insights, overcoming limitations of conventional microscale actuator analysis.
Se‐Hyeong Jung   +4 more
wiley   +1 more source

Chemically Driven Nano‐Elastic Heterogeneities Control Fragility in Volcanic Melts

open access: yesAdvanced Science, EarlyView.
The study elucidates how nanoscale structural heterogeneity governs the mechanical behavior of volcanic glasses across compositions from basalt to rhyolite. Using a physicochemical framework, correlation length (ξ) and microscopic free volume (Vc) are derived from vibrational and physical properties, revealing systematic trends with silica content that
Michele Cassetta   +13 more
wiley   +1 more source

Nanoparticle Adjuvant Design Enhances Germinal Center Responses Targeting Conserved Subdominant Epitopes for Pan‐Coronavirus Vaccine Development

open access: yesAdvanced Science, EarlyView.
Current SARS‐CoV‐2 vaccines generate short‐lived, strain‐specific immunity. A polymeric TLR7 agonist nanoparticle (TLR7‐NP) adjuvant enhances lymph node targeting and promotes early and sustained germinal center responses toward conserved S2 epitopes of the spike protein.
Sijin Huang   +12 more
wiley   +1 more source

Bose-Einstein Condensates in Optical Lattices

open access: diamond, 2002
Wojciech Wasilewski   +2 more
openalex   +1 more source

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