Results 91 to 100 of about 21,101 (266)

Impact of FSHB and FSHR Genes Polymorphisms on Hormonal Profile and Sperm Retrieval Outcome in Men With Klinefelter Syndrome: A Clinical–Genetic Predictive Study

Andrology, EarlyView.
ABSTRACT Background Genetic variability within the follicle‐stimulating hormone (FSH)‐related genes might contribute to phenotypic heterogeneity in patients with Klinefelter syndrome (KS), yet its clinical impact on sperm retrieval remains unclear. Objectives To investigate the association between FSHB c.211 G > T and FSHR polymorphisms (c.2039 A > G ...
Andrea Graziani, Giuseppe Grande, Maria Santa Rocca, Massimo Iafrate, Riccardo Selice, Antonella Di Mambro, Alberto Ferlin   +6 more
wiley   +1 more source

In Vitro Sperm–Epididymosomes Interaction Immediately Before Fertilization Changes Sperm Fertility Potential

Andrology, EarlyView.
ABSTRACT Background Sperm acquire fertility ability during epididymal maturation mainly in the epididymal caput and corpus, and once matured, are stored in the epididymal cauda. During storage, interactions with cauda epididymosomes (epEVs) may influence sperm fertility potential; however, the role of such interactions on sperm fertility remains ...
Maíra Bianchi Rodrigues Alves, Maria Alice de Almeida, Ana Beatriz Bossois Moura, Laura Gabrielli Haupenthal, Raissa Braido Rangel, Flávio Vieira Meirelles, Juliano Coelho da Silveira, Felipe Perecin   +7 more
wiley   +1 more source

Loss‐of‐Function Variants in CCDC189 Cause Human Oligoasthenoteratozoospermia by Disrupting Sperm Flagellar and Acrosomal Architecture

Andrology, EarlyView.
ABSTRACT Background Oligoasthenoteratozoospermia (OAT), characterized by reduced sperm count, impaired motility, and abnormal morphology, is a major cause of male infertility with substantial genetic heterogeneity. However, the underlying genetic etiology remains unresolved in a large proportion of affected individuals.
Jianteng Zhou, Ghulam Mustafa, Tingting Lin, Jingwei Ye, Huan Zhang, Hanwei Jiang, Kexin Yang, Guoning Huang, Qinghua Shi   +8 more
wiley   +1 more source

Pathophysiology of Premature Ejaculation

The Journal of Sexual Medicine, 2011
ABSTRACTIntroductionAlthough the characteristics of premature ejaculation (PE) are established, the exact aetiology is largely unknown. Genetic, neurobiological, pharmacological, psychological, urological and endocrine factors have all been proposed. In addition PE and erectile dysfunction are often co-morbid.AimThis article provides an overview of the
openaire   +2 more sources

Focal therapy using a novel cooled laser device for prostate cancer: early trial results

BJU International, EarlyView.
Objectives To determine the short‐term oncological results and safety of the ProFocal Laser Therapy for Prostate Tissue Ablation (PFLT‐PC) trial, the first phase II clinical trial of ProFocal® (Medlogical Innovations, Sydney, Australia), a novel, cooled laser focal therapy (cLFT) device for prostate cancer (PCa) treatment. Patients and Methods Men with
Jonathan Kam, Bishoy Hanna, Stuart Jackson, Stephen McCombie, George McClintock, Matthew J. Roberts, Jake Rahkala, Jeremy Teoh, Mohan Arianayagam, Bertram Canagasingham, Ahmed Saeed Goolam, Nicola Jeffery, Matthew Winter, Mohamed Khadra, Raymond Ko, Nicholas Mehan, Isaac Thangasamy, Celi Varol   +17 more
wiley   +1 more source

6‐Nitrodopamine Release From Mouse Seminal Vesicles Is Dependent on Endothelial Nitric Oxide Synthase (eNOS) Activation

Pharmacology Research & Perspectives
Human seminal vesicles present basal release of epithelium‐derived 6‐nitrodopamine (6‐ND) and this catecholamine potentiates noradrenaline‐induced contractions.
José Britto‐Júnior, Pérola Rafaella Cedano Godoy, Denis Oliveira Lima, Valéria B. deSouza, André A. Schenka, Fernanda V. Mariano, Felipe Fernandes Jacintho, Idam Hermawan, Hiroaki Shimokawa, Masato Tsutsui, Silvana Chiavegatto, Edson Antunes, Gilberto De Nucci   +12 more
doaj   +1 more source

Spontaneous miscarriage after intracytoplasmic sperm injection with frozen sperm of patients with testicular germ cell tumour

BJU International, EarlyView.
Objective To clarify the impact of chromosomal aberrations on the offspring of patients with testicular germ cell tumour (TGCT) by evaluating the outcomes of intracytoplasmic sperm injection (ICSI). Patients and Methods Under the ethical review of Yokohama City University, 12 patients with TGCT and 25 with non‐TGCT cancer who had cryopreserved sperm ...
Haru Hamada, Akifumi Ijuin, Tomonari Hayama, Naoki Tsuchiya, Sumiko Sueyoshi, Misaki Toda, Ai Miyakoshi, Mayuko Kurumizaka, Marina Saito, Yuki Oike, Hiroe Ueno, Shinnosuke Kuroda, Kazumi Takeshima, Teppei Takeshima, Shin Saito, Ryoko Asano, Taichi Mizushima, Yasushi Yumura, Hideya Sakakibara, Etsuko Miyagi, Miki Tanoshima, Mariko Murase   +21 more
wiley   +1 more source

Comparison of Current International Guidelines on Premature Ejaculation: 2024 Update

Diagnostics
Premature ejaculation (PE) is a common male sexual dysfunction that can cause significant distress in the patient and partner. This study aimed to compare the current international guidelines on PE to highlight their similarities and differences.
Lorenzo Romano, Davide Arcaniolo, Lorenzo Spirito, Carmelo Quattrone, Francesco Bottone, Savio Domenico Pandolfo, Biagio Barone, Luigi Napolitano, Francesco Ditonno, Antonio Franco, Felice Crocetto, Javier Romero-Otero, Riccardo Autorino, Marco De Sio, Celeste Manfredi   +14 more
doaj   +1 more source

Various dimensions of sexual self‐concept in middle‐aged men after vasectomy: a matched analysis

BJU International, EarlyView.
Objectives To compare men with and without vasectomy across four dimensions of sexual self‐concept—toughness, body image, sexual self‐esteem, and perceived pressure with regard to sexuality—and to examine differences in sexual behaviour and psychosocial factors.
Lilly J. Schmalbrock, Camille Nöckel, Valentin H. Meissner, Matthias Jahnen, Stefan Schiele, Martina Kron, Helga S. Schulwitz, Andreas Dinkel, Jürgen E. Gschwend, Kathleen Herkommer   +9 more
wiley   +1 more source

Ejaculation: Physiology and Dysfunction

Veterinary Clinics of North America: Equine Practice, 1992
In summary, important events of ejaculation include emission of sperm and the accessory gland fluids into the urethra, simultaneous closure of the bladder neck, and forceful ejaculation of the combined semen through the urethra. Emission and bladder neck closure are primarily alpha-adrenergically mediated thoracolumbar sympathetic reflex events with ...
openaire   +2 more sources