Results 251 to 260 of about 115,118 (303)

The prevalence of exocrine pancreatic insufficiency in diabetes mellitus - a multicentre study. [PDF]

Prz Gastroenterol
Kadaj-Lipka R, Wynimko M, Borowska K, Franek E, Mądro A, Skrzydło-Radomańska B, Cichoż-Lach H, Włodarczyk B, Małecka-Wojciesko E, Czkwianianc E, Adrych K, Głuszek S, Kozieł D, Rydzewska G.   +13 more
europepmc   +1 more source

Microblasting Wound Dressings Mechanically Disrupt Polymicrobial Biofilms to Enhance Healing in Treatment‐Resistant Wounds

Advanced Science, Volume 13, Issue 50, 7 September 2026.
Treatment‐resistant wounds caused by polymicrobial biofilms are refractory to conventional therapies due to the dense extracellular matrices. We developed μBLAST, a microblasting wound dressing that combines MnO2‐doped biosilica and a H2O2‐releasing mesh to generate localized oxygen microbubbles that mechanically disrupt biofilms.
Yujin Ahn, Joo Hun Lee, Christian Hurd, Jiye Lee, Junggeon Park, Adam A. Markowicz, Zheyuan Zhang, Joanne Hwang, Guillermo L. Monroy, Simon A. Rogers, Woonggyu Jung, Stephen A. Boppart, Hyunjoon Kong   +12 more
wiley   +1 more source

Delivery of Mitochondria Attenuates Elastase-Induced Abdominal Aortic Aneurysm in Mice. [PDF]

Circ Res
Cai D, Zhou R, Chen SY.
europepmc   +1 more source

p300 Degradation by the p53‐SIAH1 Axis Relieves TBK1 Acetylation to Enhance Innate Antiviral Immunity

Advanced Science, Volume 13, Issue 50, 7 September 2026.
This study identifies p300 as the acetyltransferase that acetylates TBK1 and inhibits its phosphorylation. Activation of the p53‐SIAH1 axis by immune response downregulates p300 expression to sustain innate antiviral immunity. Conditional p300 knockout in alveolar epithelial cells in vivo promotes antiviral responses and suppresses virus replication ...
Huidi Yu, Zhihao Zhan, Xiaoxiang Pan, Xinyue Zhang, Penggang Liu, Jing Sun, Xiulong Xu   +6 more
wiley   +1 more source

MLL1 Regulates T-Cell Phenotype via Notch Signaling During Abdominal Aortic Aneurysm Development. [PDF]

Arterioscler Thromb Vasc Biol
He X, Juriga N, Callow B, Salih S, Joshi A, Bogle R, Tsoi LC, Obi AT, Gudjonsson JE, Gallagher KA, Davis FM.   +10 more
europepmc   +1 more source

A Blood‐Derived Double‐Network Hydrogel with Robust Wet Adhesion for Keratinized Mucosa Regeneration via Neutrophil Phenotype Reprogramming and Mechanophysical Niche Modulation

Advanced Science, Volume 13, Issue 51, 14 September 2026.
The iPRF‐MA/Alg‐NHS/Lut@EGCG (PGAE) double‐network hydrogel achieves durable wet adhesion in the oral environment. It simultaneously reprograms neutrophils from NETosis to phagocytosis for biofilm clearance, and activates the FAK‐RhoA‐YAP mechanotransduction pathway in gingival fibroblasts to drive extracellular matrix remodeling, thereby promoting ...
Sicong Ren, Xinting Yang, Jingxia Chen, Yihan Wang, Jian Feng, Jing Zhou, Jiaxin Luo, Jingjie Zhai, Quan Lin, Yanmin Zhou   +9 more
wiley   +1 more source

Dual inhibition of neutrophil superoxide generation and elastase release <i>via</i> JNK, ERK and FAK pathways: blockade by methoxy-chalcone derivatives. [PDF]

RSC Adv
El-Gamil DS, Hammam MA, Emad M, Hafez DE, El-Shazly M, Chen YC, Wang YH, Kung PH, Korinek M, Hwang TL, Abdel-Halim M.   +10 more
europepmc   +1 more source

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, Volume 4, Issue 3, September 2026.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source

Immature Neutrophil Phenotype and Enhanced Myeloperoxidase in Male Patients With Chronic Kidney Disease and Cardiovascular Comorbidity. [PDF]

Acta Physiol (Oxf)
Vondenhoff S, Antwerpen A, Junho CVC, Martin P, Hourtz S, Zou J, Kurt B, Haas C, Fleig S, Schulte C, Lauxen J, Wessiepe M, Späte-Schulze U, Kramann R, Floege J, Soehnlein O, Jankowski J, Goettsch C, Döring Y, Kahles F, Marx N, Baaten CCFMJ, Noels H.   +22 more
europepmc   +1 more source

Harnessing blood clot as a native scaffold for orchestrating tissue repairs and regeneration

BMEMat, Volume 4, Issue 3, September 2026.
The blood clot, owing to its dynamic composition and unique microenvironment, holds significant yet underappreciated potential for tissue engineering. This review systematically summarizes the pathophysiology of clot formation, the key regulatory factors shaping its microenvironment, and its applications in both pre‐clinical and clinical settings ...
Gao‐peng Dang, Yu‐zhu Wang, Yi‐fei Wang, Que Bai, Jia‐xin Hao, Zhi‐ting Li, Xiao‐qing Cao, Yu Wei, Yue Feng, Ji‐hua Chen, Franklin R. Tay, Rui‐bing Wang, Jun‐ting Gu, Li‐na Niu   +13 more
wiley   +1 more source