Results 291 to 300 of about 126,008 (360)

The Interface of Oral and Brain Health: Current Insights Into the Bidirectional Relationship Between Alzheimer's Disease and Periodontitis

CNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
Bidirectional Pathogenesis Between AD and Periodontitis. Periodontal pathogens reach the brain via hematogenous/trigeminal/oral–intestinal pathways, triggering neuroinflammation and Aβ plaques to drive AD. Conversely, AD disrupts bone homeostasis (via Aβ, endocrine/autonomic dysregulation) to aggravate periodontitis.
Weidong Zhang, Shasha Li, Yajun Cui, Yuhui Lun, Hongrui Liu, Minqi Li   +5 more
wiley   +1 more source

Pyroptosis in Peripheral Neuropathy: From Molecular Mechanisms to Therapeutic Targeting

CNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
Pyroptosis is a key inflammatory cell death pathway in peripheral neuropathy, with opposing roles: it perpetuates neuropathic pain but can be induced to kill neuroblastoma cells. This review consolidates mechanistic understanding and therapeutic strategies, arguing for a shift from disease‐centric to target‐centric treatment approaches to improve ...
Jinhuan Wei, Mingyue Liuyuan, Zhixin Ye, Xueying Wang, Xueli Zhou, Yifan Shan, Cheng He, Chunting Zhu, Chicheng Zhou, Jingyin Bao, Yonghui Zhang, Gang Chen   +11 more
wiley   +1 more source

Chemical profile, antioxidant capacity, cytotoxicity, and dual enzymatic inhibition of Sloanea medusula K.Schum. & Pittier leaves for cosmeceutical applications. [PDF]

Sci Rep
Quintero-Rincón P, Quintero-Marulanda P, Garzón-Rojas A, Pino-Benitez N, Flórez-Acosta O.   +4 more
europepmc   +1 more source

Breakdown of C3 complement and IgG in peritonitis exudate-pathophysiological aspects and therapeutic approach [PDF]

, 1988
Billing, A., Fröhlich, D., Jochum, Marianne, Kortmann, H., Redl, H., Schlag, G.   +5 more
core  

Multi‐omics analysis identifies PUS7 as an immune modulator driving NETs‐mediated macrophage polarization in pancreatic cancer

Clinical and Translational Medicine, Volume 16, Issue 1, January 2026.
PUS7 reshapes the PDAC immune landscape primarily by inducing NETs, which drive macrophage polarization from M1 to M2, fostering immune suppression and tumour progression. The inhibitory effects of S428‐1145 and DNase I on pancreatic cancer are mediated through blocking the PUS7/NETs/M2 macrophage pathway.
Jike Fang, Shiye Ruan, Yajie Wang, Yue Chen, Fuxin Huang, Zhongyan Zhang, Chuanzhao Zhang, Baohua Hou, Shanzhou Huang   +8 more
wiley   +1 more source

Correction: Neutrophils as key drivers of pulmonary fibrosis: unveiling mechanisms and therapeutic implications. [PDF]

Front Immunol
Liang X, Li Y, Tang Z, Luo Y, Liu Y.
europepmc   +1 more source

Basti treatment improved faecal calprotectin and faecal elastase of a patient of inflammatory bowel disease with sarcoidosis - a case report. [PDF]

J Ayurveda Integr Med
Kora RK, Madikonda PK, Johar B.
europepmc   +1 more source

Neutrophils as key drivers of pulmonary fibrosis: unveiling mechanisms and therapeutic implications. [PDF]

Front Immunol
Liang X, Li Y, Tang Z, Luo Y, Liu Y.
europepmc   +1 more source

In vitro and in vivo exploration of microbiome-derived yeast extract for anti-aging and skin rejuvenation. [PDF]

BMC Microbiol
Nguyen NH, Lee YI, Jang YS, Lee HK, Jung I, Lee SJ, Lee JH.   +6 more
europepmc   +1 more source

Multidisciplinary Bioanalytical Approach to Assess the Anti-Aging Properties of Flower Petals-A Promising Sustainable Cosmetic Ingredient. [PDF]

Plants (Basel)
Ivković Đ, Senćanski M, Novković M, Stojković-Filipović J, Trifković J, Ristivojević P, Krstić Ristivojević M.   +6 more
europepmc   +1 more source