Results 1 to 10 of about 14,181 (179)

Detection of human elastase isoforms by the ScheBo Pancreatic Elastase 1 Test [PDF]

American Journal of Physiology - Renal Physiology, 2017
Determination of fecal pancreatic elastase content by ELISA is a reliable, noninvasive clinical test for assessing exocrine pancreatic function. Despite the widespread use of commercial tests, their exact molecular targets remain poorly characterized.
Balázs Csaba Nemeth, András SZABÓ, Eszter Hegyi   +2 more
exaly   +6 more sources

Negative impact of reduced exocrine pancreatic function on sarcopenia risk in the asymptomatic general population [PDF]

Frontiers in Nutrition
BackgroundIn patients with pancreatic disease, exocrine insufficiency facilitates sarcopenia. Here, we investigated whether impaired exocrine function in the asymptomatic general population is also associated with sarcopenia.MethodsWe pooled data from ...
Mats L. Wiese, Mats L. Wiese, Giancarlo Paradiso, Fabian Frost, Sabrina von Rheinbaben, Martin Bahls, Martin Bahls, Till Ittermann, Henry Völzke, Markus M. Lerch, Frank Ulrich Weiss, Ali A. Aghdassi   +11 more
doaj   +2 more sources

Inhibition of pancreatic elastase in silico and in vitro by Rubus rosifolius leaves extract and its constituents [PDF]

Journal of Pharmacy and Bioallied Sciences, 2020
Objective: Elastases are protease enzymes, which mainly hydrolyze proteins of the connective tissue, so they have a significant impact on human disease.
Yesi Desmiaty, Esti Mulatsari, Fadlina Chany Saputri, Muhammad Hanafi, Rini Prastiwi, Berna Elya   +5 more
doaj   +2 more sources

Clinical and Analytical Comparison of Monoclonal and Polyclonal Immunoassays for Fecal Pancreatic Elastase [PDF]

Diagnostics
Background: Numerous immunoassays have been commercialized to determine pancreatic elastase (PE) in feces in screening for exocrine pancreatic insufficiency (EPI), but how the different assays compare to one another is controversial, especially in the ...
Jasna Lenicek Krleza, Merica Aralica, Lara Milevoj Kopcinovic, Renata Zrinski Topic   +3 more
doaj   +2 more sources

Shifts in amino acids profile in chronic pancreatitis. [PDF]

PLoS ONE
BackgroundChronic pancreatitis (CP) can lead to pancreatic exocrine insufficiency (PEI), causing protein malabsorption and altered amino acid levels.
Marko Malvik, Kalle Kilk, Raili Müller, Riina Salupere, Mihkel Zilmer, Margus Lember   +5 more
doaj   +2 more sources

Specificity of a Polyclonal Fecal Elastase ELISA for CELA3. [PDF]

PLoS ONE, 2016
Elastase is a proteolytic pancreatic enzyme that passes through the gastrointestinal tract undergoing only limited degradation. ELISA tests to determine stool elastase concentrations have therefore been developed for the diagnosis of exocrine pancreatic ...
Frank Ulrich Weiss, Christoph Budde, Markus M Lerch   +2 more
doaj   +1 more source

Quantitative Edge Analysis of Pancreatic Margins in Patients with Chronic Pancreatitis: A Correlation with Exocrine Function

Diagnostics, 2023
Background: Many efforts have been made to improve accuracy and sensitivity in diagnosing chronic pancreatitis (CP), obtaining quantitative assessments related to functional data.
Maria Chiara Ambrosetti, Annamaria Grecchi, Alberto Ambrosetti, Antonio Amodio, Giancarlo Mansueto, Stefania Montemezzi, Giulia A. Zamboni   +6 more
doaj   +1 more source

Prediction of pancreatic fistula after pancreatoduodenectomy by preoperative dynamic CT and fecal elastase-1 levels. [PDF]

PLoS ONE, 2017
To validate preoperative dynamic CT and fecal elastase-1 level in predicting the development of pancreatic fistulae after pancreatoduodenectomy.For 146 consecutive patients, CT attenuation values of the nontumorous pancreatic parenchyma were ...
Jung-Hyun Kang, Joon Seong Park, Jeong-Sik Yu, Jae-Joon Chung, Joo Hee Kim, Eun-Suk Cho, Dong Sup Yoon   +6 more
doaj   +1 more source

Accuracy of simultaneous measurement of serum biomarkers: Carbohydrate antigen 19-9, pancreatic elastase-1, amylase, and lipase for diagnosing pancreatic ductal adenocarcinoma

Journal of the Formosan Medical Association, 2022
Background: Pancreatic cancer is difficult to diagnose early since tumor markers have low sensitivity and specificity. We simultaneously measured serum carbohydrate antigen (CA) 19-9, pancreatic elastase-1, lipase, and amylase, and evaluated the accuracy
Chi-Ying Yang, Ro-Ting Lin, Chi-Yi Chen, Chun-Chieh Yeh, Chao-Ming Tseng, Wen-Hsin Huang, Teng-Yu Lee, Chia-Shen Chu, Jaw-Town Lin   +8 more
doaj   +1 more source

Difference in the Faecal Elastase-1 Concentration between Resectable and Unresectable Pancreatic Cancer

The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy, 2020
Background: In the pancreatic cancer can occur pancreatic exocrine insufficiency (PEI) that can be detected by measurement of fecal elastase-1 level. The aim of this study was to identify the proportion and the degree of PEI, proportion of steatorrhea in
Abdul Rahman M, Marcellus Simadibrata, Irsan Hasan, Suhendro Suhendro, E Mudjadid   +4 more
doaj   +1 more source