Results 31 to 40 of about 253,620 (220)

Enhanced release of elastase is not concomitant with increased secretion of granulocyte-activating cytokines in whole blood from patients with sepsis [PDF]

open access: yes, 1994
Die Diskussion am Ende des Artikels wurde gelöscht (§137l UrhG).Background The proteolytic enzyme elastase released by granulocytes (polymorphonuclear leukocytes [PMN]) in high concentrations during sepsis causes degradation of essential plasma proteins,
Schildberg, Friedrich-Wilhelm   +7 more
core   +1 more source

Exocrine pancreatic function is preserved in systemic sclerosis

open access: yesArthritis Research & Therapy, 2019
Background Systemic sclerosis (SSc) has been suggested to cause exocrine pancreatic dysfunction. However, a case-control-based autopsy study failed to associate systemic sclerosis with any pancreatic histopathology.
Gracijela Bozovic   +7 more
doaj   +1 more source

Influence of SPK with Enteric Drainage on the Pancreatic Exocrine Function in Diabetic Patients with Uremia

open access: yesInternational Journal of Endocrinology, 2017
Objective. This study aimed to determine the use of fecal elastase in evaluating the effect of simultaneous pancreas–kidney transplantation with enteric drainage on the pancreatic exocrine function of diabetic patients with uremia. Methods. A total of 19
Guanghui Pei   +4 more
doaj   +1 more source

Fecal pancreatic elastase-1 levels in older individuals without known gastrointestinal diseases or diabetes mellitus

open access: yesBMC Geriatrics, 2011
Background Structural changes occur in the pancreas as a part of the natural aging process. With aging, also the incidence of maldigestive symptoms and malnutrition increases, raising the possibility that these might be caused at least in part by ...
Idziak Joanna   +6 more
doaj   +1 more source

Local lung responses following endobronchial elastase and lipopolysaccharide instillation in sheep [PDF]

open access: yes, 2006
Chronic lipopolysaccharide (LPS) exposure may contribute to the pathogenesis of a number of lung diseases including COPD and emphysema. We sought to develop a large-animal model of emphysema using repeated LPS administration into sheep lung segments.
Blundell, Richard   +8 more
core   +1 more source

Molecular Elucidation of Pancreatic Elastase Inhibition by Baicalein [PDF]

open access: yesJournal of Biomolecular Structure and Dynamics, 2020
ABSTRACT The serine protease, elastase exists in various forms and plays diverse roles in the human body. Pharmacological inhibition of elastase has been investigated for its therapeutic role in managing conditions such as diabetes, pneumonia and arthritis.
Debajeet Ghosh   +4 more
openaire   +3 more sources

Fecal elastase-1: Utility in pancreatic function in cystic fibrosis [PDF]

open access: yes, 2006
Early detection and management of pancreatic insufficiency is essential to optimize health and outcomes in cystic fibrosis patients. The gold standard measures for assessment of pancreatic function are direct pancreatic stimulation tests, which have ...
Daftary, Ameet   +3 more
core   +1 more source

The specificity of purified porcine pancreatic elastase [PDF]

open access: yesBiochemical Journal, 1969
An electrophoretically homogeneous elastase preparation free from tryptic and chymotryptic activities was obtained by chromatography on DEAE-Sephadex and CM-cellulose. This preparation exhibits a narrower specificity towards peptide bonds than that observed by Naughton & Sanger (1961).
A S, Narayanan, R A, Anwar
openaire   +2 more sources

Safety evaluation of a food enzyme containing trypsin, chymotrypsin, elastase and carboxypeptidase from porcine pancreas

open access: yesEFSA Journal, 2021
The food enzyme is a protease complex, containing trypsin (EC 3.4.21.4), chymotrypsin (EC 3.4.21.1), pancreatic elastase (EC 3.4.21.36) and carboxypeptidase B (EC 3.4.17.2), obtained from porcine pancreas by Neova Technologies Inc.
EFSA Panel on Food Contact Materials, Enzymes and Processing Aids (CEP)   +28 more
doaj   +1 more source

Prevalence of end-organ damage, beta cell reserve, and exocrine pancreas defect in fibrocalculous pancreatic diabetes: An Eastern India perspective

open access: yesIndian Journal of Endocrinology and Metabolism, 2019
Background: Data on prevalence and burden of end-organ damage in fibrocalculous pancreatic diabetes (FCPD) from eastern India is scant. This study investigated the burden of end-organ damage and exocrine pancreatic defect in FCPD patients in Eastern ...
Beatrice Anne   +5 more
doaj   +1 more source

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