Results 51 to 60 of about 253,620 (220)

Assessment of Exocrine Pancreatic Insufficiency in Type 2 Diabetic Mellitus Patients Presenting with Dyspepsia: A Cross-sectional Observational Study [PDF]

open access: yesAvicenna Journal of Medical Biochemistry
Background: Diabetes mellitus (DM) virtually affects the gastrointestinal (GI) tract in protean ways, including but not limited to small intestinal bacterial overgrowth, GI reflux disease, gastroparesis, neuropathy, pancreatopathy, and non-alcoholic ...
Nidhi Bhutra, Ravi Kant
doaj   +1 more source

Pathophysiological Mechanisms of Emaciation Syndrome in Plectropomus leopardus: Insights From Histology and Transcriptomics

open access: yesAnimal Research and One Health, EarlyView.
Integrated phenotypic, histological, transcriptomic, and validation analyses reveal that emaciation syndrome in Plectropomus leopardus is associated with intestinal structural damage, hepatic metabolic remodeling, and muscle protein degradation, highlighting coordinated multi‐tissue alterations underlying disease progression.
Zhihao Zhang   +11 more
wiley   +1 more source

Evaluation of Ionic Liquids and Ionic Liquids Active Pharmaceutical Ingredients Inhibition in Elastase Enzyme Activity

open access: yesMolecules, 2021
Human neutrophil elastase (HNE) is used as diagnostic biomarker for inflammation/infection. In this work, 10 ionic liquids (ILs) and 11 ionic liquids active pharmaceutical ingredients (ILs-APIs) were tested to evaluate the inhibition effect on the ...
Fátima A. R. Mota   +3 more
doaj   +1 more source

MurNAc‐Based Electrophilic Inhibitors of O‐Acetylpeptidoglycan Esterase (Ape): Design, Synthesis, and Kinetic Evaluation

open access: yesChemistry – A European Journal, EarlyView.
A series of N‐acetylmuramic acid (MurNAc)‐based electrophilic inhibitors targeting Ape esterase was synthesized. Their inhibitory potency ranged from micromolar to submillimolar. The study probed binding contributions of stem peptide extension, replacing the anomeric methyl group with a benzyl, and α‐fluorination of the carbonyl to enhance ...
Dmytro Voskoboinyk, Martin E. Tanner
wiley   +1 more source

New directions in diagnosis and treatment of canine acute pancreatitis [PDF]

open access: yes, 2011
Acute pancreatitis is an important disease in companion animal medicine, and diagnostic methodology available to veterinary practitioners is often limited. Evidence based principles for the management of this common disease are also lacking.
Mansfield, Caroline S.
core  

Human biomarker navigator

open access: yesiMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li   +29 more
wiley   +1 more source

Pancreatic function in children with non-alcoholic fatty pancreas disease

open access: yesZaporožskij Medicinskij Žurnal, 2019
Objective. To study the features of pancreatic function in children with pancreatic steatosis. Materials and methods. We examined 77 children; the average age of patients was (11.59 ± 2.82) years.
Yu. M. Stepanov   +5 more
doaj   +1 more source

Diagnostic Efficacy of Fecal Elastase-1 in Patients with Chronic Pancreatitis Diagnosed by Endoscopic Ultrasound [PDF]

open access: yesAl-Azhar International Medical Journal, 2000
Background: Pancreatic insufficiency in chronic pancreatitis (CP) is commonly underdiagnosed and undertreated. Endoscopic ultrasound (EUS) can diagnose CP more accurately.
Yousry Hashim   +4 more
doaj   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Urinary elastase 1 in chronic pancreatic disease

open access: yes, 1989
Serum and urine elastase 1, its renal output and clearance and urinary gamma-glutamyltransferase and ribonuclease excretions were measured in 16 patients with pancreatic cancer, 23 with chronic pancreatitis and in 22 healthy controls in order to evaluate
M. P. Panozzo   +9 more
core   +1 more source

Home - About - Disclaimer - Privacy