Results 51 to 60 of about 920,917 (297)

Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling

FEBS Open Bio, EarlyView.
Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt, Annika Winbo, Jenny Malmström   +2 more
wiley   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Unraveling Elastic Fiber-Derived Signaling in Arterial Aging and Related Arterial Diseases

Biomolecules
Arterial stiffening is a significant risk factor for the development of cardiovascular diseases, including hypertension, atherosclerosis, and arteriopathy.
Mingyi Wang, Kimberly R. McGraw, Robert E. Monticone, Gianfranco Pintus   +3 more
doaj   +1 more source

Qualitative and quantitative characterization of the Rhesus monkey (Macaca mulatta) penis [PDF]

International Brazilian Journal of Urology
Background: Knowledge of the anatomy of laboratory animals is important for experimental research. Erectile dysfunction has been studied using the penises of different laboratory animals such as rats, mice, rabbits, dogs, etc. However, these animals have
Marcelo Abidu-Figueiredo, Edilaine F. Alves, Carla B. M. Gallo, Waldemar S. Costa, Luciano A. Favorito, Francisco J. B. Sampaio   +5 more
doaj   +1 more source

Energy harvesting from sonic noises by phononic crystal fibers

Scientific Reports, 2022
In this investigation, a phononic crystal-based fiber is proposed for energy harvesting application in metalworking factories. Phononic crystal plays the role of cladding in elastic fiber structure.
Farzaneh Motaei, Ali Bahrami
doaj   +1 more source

Tropoelastin and Elastin Assembly

Frontiers in Bioengineering and Biotechnology, 2021
Elastic fibers are an important component of the extracellular matrix, providing stretch, resilience, and cell interactivity to a broad range of elastic tissues.
Jazmin Ozsvar, Jazmin Ozsvar, Chengeng Yang, Stuart A. Cain, Clair Baldock, Anna Tarakanova, Anna Tarakanova, Anthony S. Weiss, Anthony S. Weiss, Anthony S. Weiss   +9 more
doaj   +1 more source

High Resolution and Labeling Free Studying the 3D Microstructure of the Pars Tensa-Annulus Unit of Mice

Frontiers in Cell and Developmental Biology, 2021
Hearing loss is a serious illness affecting people’s normal life enormously. The acoustic properties of a tympanic membrane play an important role in hearing, and highly depend on its geometry, composition, microstructure and connection to the ...
Jian-Ping Wu, Jian-Ping Wu, Xiaojie Yang, Yilin Wang, Ben Swift, Robert Adamson, Yongchang Zheng, Rongli Zhang, Wen Zhong, Fangyi Chen, Fangyi Chen   +10 more
doaj   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Unusual remodeling of the hyalinization band in vulval lichen sclerosus by type V collagen and ECM 1 protein

Clinics, 2015
OBJECTIVES: The vulva is the primary site affected in lichen sclerosus, a chronic dermatosis in women that is histologically characterized by a zone of collagen remodeling in the superior dermis. The normal physiological properties of the vulva depend on
Charles A.P. Godoy, Walcy R. Teodoro, Ana Paula P. Velosa, Ana Lucia Garippo, Esmeralda Miristeni Eher, Edwin Roger Parra, Mirian N. Sotto, Vera L. Capelozzi   +7 more
doaj   +1 more source

Electron dense staining affinities of mouse oxytalan and elastic fibers [PDF]

, 1980
. The staining affinity of electron dense stains to mouse palatal elastic fibers and periodontal oxytalan fibers was assessed and compared. Tissues were stained routinely with uranyl acetate and lead citrate or with elastic tissue stains including: (1 ...
Avery, James K., Simmons, T. A.
core   +1 more source