Results 151 to 160 of about 112,379 (307)

Exploring the Correlation Between Surgical Depth and Postoperative Voice Rest Duration in a Rabbit Phonomicrosurgery Model

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective The optimal duration of voice rest after phonomicrosurgery remains a subject of debate, as clinical studies on its effect on vocal fold wound healing have yielded conflicting results, and a controlled animal model for investigating voice rest is currently unavailable. This study aimed to determine the optimal postoperative voice rest
Lin‐Lin Lan   +2 more
wiley   +1 more source

In Vitro and In Vivo Evaluation of Decellularized Porcine Femoral Aorta Reinforced With Electrospun Coarse Polycaprolactone Fibers for Vascular Graft Application

open access: yesArtificial Organs, EarlyView.
This study aims to develop a hybrid small‐diameter vascular graft by combining electrospun PCL with decellularized porcine femoral aorta (PECM). The graft showed complete decellularization, strong mechanical integrity, and no layer delamination.
Hyun‐Yong Lee   +8 more
wiley   +1 more source

Identification of Autologous Tissue Sources and Optimization of a Treatment Method for Intraoperative Manufacturing of Heart Valve Constructs

open access: yesArtificial Organs, EarlyView.
The use of autologous connective tissue, such as pericardium or peritoneum, combined with controlled tissue treatment, has the potential to result in a more durable heart valve prosthesis than current commercial prostheses. ABSTRACT Introduction Valvular heart disease remains a leading cause of morbidity and mortality. Current biological and mechanical
Marvin Steitz   +17 more
wiley   +1 more source

Thrombospondin‐4 is upregulated in abdominal aortic aneurysm: A vasoprotective response with potential therapeutic relevance

open access: yesBritish Journal of Pharmacology, EarlyView.
TSP4 is upregulated in human and experimental AAA. TSP4 knockdown accelerated AAA formation and exacerbated both vascular inflammation and remodelling, emphasizing that TSP4 upregulation may represent a protective response against AAA. Our findings suggest that preserving TSP4 could be a useful strategy in the clinical management of AAA.
Laia Blanco‐Casoliva   +10 more
wiley   +1 more source

Extracellular matrix and proteolysis: mechanisms driving irreversible changes and shaping cell behavior

open access: yesThe FEBS Journal, EarlyView.
Irreversible ECM proteolysis by remodeling enzymes shapes development, homeostasis, and disease. ECM‐degrading proteases display cell specificity and are governed by shared mechanisms, exhibiting functional redundancy in generating matrikines, growth factors, and cytokines.
Inna Solomonov, Orit Kollet, Irit Sagi
wiley   +1 more source

A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

open access: yesThe FEBS Journal, EarlyView.
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou   +4 more
wiley   +1 more source

Decoding elastin-collagen resemblance in keloid scar through label-free imaging and machine learning. [PDF]

open access: yesJ Biomed Opt
Wang C   +12 more
europepmc   +1 more source

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