Results 151 to 160 of about 76,474 (248)

Construction and expression of recombinant human elastin with biological activities: effect of wound healing <i>in vitro</i> and <i>in vivo</i>. [PDF]

Front Bioeng Biotechnol
Zhang X, Zhou E, Liao B, Wang Y, Xiong C, Jin M, Qin P, Xiong S.   +7 more
europepmc   +1 more source

Repositioning Non‐Ablative Fractional Lasers ‐ Molecular and Histological Insights from a scoping review

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Near‐infrared non‐ablative fractional lasers (NAFL) are established for skin rejuvenation and scar treatment and have attracted interest for their expanding therapeutic potential. This scoping review aims to revisit and reposition NAFL within a fluence‐dependent continuum of tissue modulation, based on evidence from 27 studies of lasers ...
Guy Erlich, Uwe Paasch, Kevin Jacobsen, Merete Haedersdal, Uffe Høgh Olesen   +4 more
wiley   +1 more source

Sclerostin regulates bone morphogenetic protein (BMP) bioavailability through interactions with BMP complexes and fibrillin microfibrils

The FEBS Journal, EarlyView.
Sclerostin (SOST) is a multifunctional extracellular modulator of BMP and Wnt signaling. SOST binds with high affinity to fibrillin‐1 and fibrillin‐2, localizing it to fibrillin microfibrils and regulating its extracellular bioavailability. Fibrillin‐bound SOST cannot engage BMP‐7 prodomain (PD) complexes, revealing a competitive mechanism that ...
Annkatrin Correns, Fady Marcous, Steffen Lütke, Matthias Mörgelin, Philipp Barnowski, Ariane G. Furlan, Nathalie H. Schröder, Bodo Levkau, Sarah Riek, Martin Mollenhauer, Manuel Koch, Gerhard Sengle   +11 more
wiley   +1 more source

Circulating elastin fragments drive systemic aging: Where do pro-aging elastin fragments come from? A mini-review. [PDF]

Mech Ageing Dev
Quan T.
europepmc   +1 more source

Orcein is a more sensitive stain than EVG for detecting large vessel (venous) invasion in colorectal cancer

Histopathology, EarlyView.
Orcein is more sensitive than EVG for detecting intramural and extramural large vessel (venous) invasion than EVG and H&E in colorectal cancer. Background Large vessel invasion (VI) is a well‐established adverse prognostic factor in colorectal cancer (CRC).
Timothy Law, Won‐Tak Choi, Sarah E. Umetsu, Kwun Wah Wen   +3 more
wiley   +1 more source

The harnessing potential of carboxymethyl beta glucan: A driver of skin repair

International Journal of Cosmetic Science, EarlyView.
Carboxymethyl Beta‐Glucan (CM‐BG) drives skin repair through multifaceted actions, notably in wounded 3D models. It activates Dectin‐1 and mitigates inflammation (reducing pro‐inflammatory mediators, boosting anti‐inflammatory IL‐10) in cellular models, while enhancing epidermal differentiation and collagen I synthesis by fibroblasts across cellular ...
Caroline Pichon, Xavier Marat, Alice Brule, Annie Black, Audrey Gueniche   +4 more
wiley   +1 more source

Low-detergent sonication decellularization preserves extracellular matrix architecture and enhances cell infiltration in human acellular dermal matrix. [PDF]

Front Bioeng Biotechnol
Mbele M, Jay T, Khumalo NP, Bayat A.
europepmc   +1 more source

Bakuchiol: From structural mimicry to systems‐level skin biology

International Journal of Cosmetic Science, EarlyView.
Convergent outcomes, divergent mechanisms: bakuchiol vs. retinol. Bakuchiol exhibits functional convergence with retinol in improving extracellular matrix integrity, epidermal differentiation and barrier function, while operating through distinct mechanisms.
Ratan K. Chaudhuri
wiley   +1 more source

Anti-Aging Efficacy of a Home-use red and Infrared Light-Emitting Diode Mask and a Cream: Ex Vivo and Clinical Evaluations in Women With Mature Skin. [PDF]

Skin Res Technol
Bellanger A, Guéré C, Boisnic S, Godet D.   +3 more
europepmc   +1 more source

The Biological Basis of the Merlin CP‐GEP Assay: Integrin Signaling and Early Metastatic Competence in Cutaneous Melanoma

International Journal of Dermatology, EarlyView.
Merlin CP‐GEP integrates mechanistic insights into a clinically actionable assay to predict SLN metastasis risk and inform personalized management of cutaneous melanoma. ABSTRACT The recent inclusion of the Merlin clinicopathologic–gene expression profile (CP‐GEP) assay in the National Comprehensive Cancer Network (NCCN) Melanoma Guidelines represents ...
Frank Z. Jing, Alexander Meves
wiley   +1 more source