Exploring the Release of Elastin Peptides Generated from Enzymatic Hydrolysis of Bovine Elastin via Peptide Mapping [PDF]
Molecules, 2023 To enhance the understanding of enzymatic hydrolysis and to accelerate the discovery of key bioactive peptides within enzymatic products, this research focused on elastin as the substrate and investigated the variations in peptide profiles and the ...
Jianan Zhang +5 more
doaj +3 more sources
Elastin peptides in aging and pathological conditions
Biomolecular Concepts, 2013 Elastin is the protein responsible for the resilience of vertebrate tissue. It is an extremely stable protein deposited during the early stages of life and experiencing almost no renewal. As a consequence, it can be considered that each individual has an
Baud Stéphanie +8 more
doaj +3 more sources
Elastin Peptides as a Potential Disease Vector in the Pathogenesis of Pulmonary Emphysema: An Investigation of This Hypothesis [PDF]
LifeThe degradation of elastic fibers is a fundamental characteristic of pulmonary emphysema, resulting in the release of proinflammatory elastin peptides.
Jerome Cantor
doaj +2 more sources
Isolation, Purification and Characterization of Antioxidative Bioactive Elastin Peptides from Poultry Skin [PDF]
Food Science of Animal Resources, 2019 Muscle-based by-products are often undervalued although commonly reported having a high amount of natural bioactive peptides. In this study, elastin was isolated from the protein of broiler hen skin while its hydrolysate was prepared using Elastase ...
Mehdi Nadalian +4 more
doaj +2 more sources
Engineered elastin-like polypeptides: An efficient platform for enhanced cancer treatment
Frontiers in Pharmacology, 2023 Drug delivery systems (DDSs) have recently gained widespread attention for improving drug loading and delivery efficiency in treating many cancers. Elastin-like polypeptides (ELPs) are synthetic peptides derived from a precursor of elastin (tropoelastin),
Aiguo Jiang +4 more
doaj +1 more source
Recent Advances in Elastin-Based Biomaterial
Journal of Pharmacy & Pharmaceutical Sciences, 2020 Elastin is one of the main components of the extracellular matrix; it provides resistance and elasticity to a variety of tissues and organs of the human body, besides participating in cellular signaling.
María Luisa Del Prado Audelo +7 more
doaj +1 more source
The Elastin Receptor Complex: An Emerging Therapeutic Target Against Age-Related Vascular Diseases
Frontiers in Endocrinology, 2022 The incidence of cardiovascular diseases is increasing worldwide with the growing aging of the population. Biological aging has major influence on the vascular tree and is associated with critical changes in the morphology and function of the arterial ...
Dignê Tembely +12 more
doaj +1 more source
Respiratory Research, 2021 Background Elastin degradation has been established as one of the driving factors of emphysema. Elastin-derived peptides (EDPs) are shown to act as a chemoattractant for monocytes.
Vaideesh Parasaram +3 more
doaj +1 more source
Materials Today Bio, 2022 Harnessing the inflammation and angiogenesis is extremely important in wound healing. In this study, we developed bioactive elastin-based hydrogels which can recruit and modulate the innate immune cells and accelerate angiogenesis in the wound site and ...
Duo-Mei Tian +19 more
doaj +1 more source
Elastin peptides signaling relies on neuraminidase-1-dependent lactosylceramide generation. [PDF]
PLoS ONE, 2010 The sialidase activity of neuraminidase-1 (Neu-1) is responsible for ERK 1/2 pathway activation following binding of elastin peptide on the elastin receptor complex.
Anthony Rusciani +9 more
doaj +1 more source