Exploring the Release of Elastin Peptides Generated from Enzymatic Hydrolysis of Bovine Elastin via Peptide Mapping [PDF]
Molecules, 2023 To enhance the understanding of enzymatic hydrolysis and to accelerate the discovery of key bioactive peptides within enzymatic products, this research focused on elastin as the substrate and investigated the variations in peptide profiles and the ...
Jianan Zhang +5 more
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Elastin peptides in aging and pathological conditions [PDF]
Biomolecular Concepts, 2013 Elastin is the protein responsible for the resilience of vertebrate tissue. It is an extremely stable protein deposited during the early stages of life and experiencing almost no renewal. As a consequence, it can be considered that each individual has an
Baud Stéphanie +8 more
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Elastin Peptides as a Potential Disease Vector in the Pathogenesis of Pulmonary Emphysema: An Investigation of This Hypothesis [PDF]
LifeThe degradation of elastic fibers is a fundamental characteristic of pulmonary emphysema, resulting in the release of proinflammatory elastin peptides.
Jerome Cantor
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Isolation, Purification and Characterization of Antioxidative Bioactive Elastin Peptides from Poultry Skin [PDF]
Food Science of Animal Resources, 2019 Muscle-based by-products are often undervalued although commonly reported having a high amount of natural bioactive peptides. In this study, elastin was isolated from the protein of broiler hen skin while its hydrolysate was prepared using Elastase ...
Mehdi Nadalian +4 more
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Role of elastin peptides and elastin receptor complex in metabolic and cardiovascular diseases [PDF]
FEBS Journal, 2019 The Cardiovascular Continuum describes a sequence of events from cardiovascular risk factors to end‐stage heart disease. It includes conventional pathologies affecting cardiovascular functions such as hypertension, atherosclerosis or thrombosis and was traditionally considered from the metabolic point of view.
Amandine Wahart +2 more
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Molecules, 2019 A novel type of self-assembling peptides has been developed by introducing the basic elastomeric β-turn units of elastin protein into the amphiphilic peptide molecules.
Meiwen Cao +4 more
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Elastin peptides signaling relies on neuraminidase-1-dependent lactosylceramide generation. [PDF]
PLoS ONE, 2010 The sialidase activity of neuraminidase-1 (Neu-1) is responsible for ERK 1/2 pathway activation following binding of elastin peptide on the elastin receptor complex.
Anthony Rusciani +9 more
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Elastin in the Pathogenesis of Abdominal Aortic Aneurysm [PDF]
CellsAbdominal aortic aneurysms (AAAs) are progressive, life-threatening vascular disorders characterized by focal dilation of the abdominal aorta due to chronic weakening of the arterial wall.
Dunpeng Cai, Shi-You Chen
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Elastin peptides antagonize ceramide‐induced apoptosis
FEBS Letters, 2009 Elastin peptides regulate proliferation, chemotaxis and protease expression. The aim of this work was to assess their influence on apoptosis. Human skin fibroblast cell death was induced using C2‐ceramide in the presence or absence of elastin peptides. We show that ceramide‐induced apoptosis could be blocked by elastin peptides.
Laurent Duca, Stéphane Poitevin
exaly +4 more sources
Engineered elastin-like polypeptides: An efficient platform for enhanced cancer treatment
Frontiers in Pharmacology, 2023 Drug delivery systems (DDSs) have recently gained widespread attention for improving drug loading and delivery efficiency in treating many cancers. Elastin-like polypeptides (ELPs) are synthetic peptides derived from a precursor of elastin (tropoelastin),
Aiguo Jiang +4 more
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