Results 21 to 30 of about 13,438 (200)

A Fully Automatic and Efficient Methodology for Peptide Activity Identification Using Their 3D Conformations

IEEE Access, 2021
Over the past decades, the understanding of peptides and proteins biological functions has been an active research topic. Latest research works in this field have suggested that protein conformations may be a key feature for gaining insights into protein
Azzam Alwan, Remi Cogranne, Pierre Beauseroy, Edith Grall-Maes, Nicolas Belloy, Laurent Debelle, Stephanie Baud, Manuel Dauchez, Sebastien Almagro   +8 more
doaj   +1 more source

Induction and regulation of murine emphysema by elastin peptides [PDF]

American Journal of Physiology-Lung Cellular and Molecular Physiology, 2016
Emphysema is the major component of chronic obstructive pulmonary disease (COPD). During emphysema, elastin breakdown in the lung tissue originates from the release of large amounts of elastase by inflammatory cells. Elevated levels of elastin-derived peptides (EP) reflect massive pulmonary elastin breakdown in COPD patients.
Sellami, Mehdi, Meghraoui-Kheddar, Aïda, Terryn, Christine, Fichel, Caroline, Bouland, Nicole, Diebold, Marie-Danièle, Guenounou, Moncef, Héry-Huynh, Stéphanie, Le Naour, Richard   +8 more
openaire   +4 more sources

Elastin-derived peptide VGVAPG decreases differentiation of mouse embryo fibroblast (3T3-L1) cells into adipocytes

Adipocyte, 2020
Elastin is a highly elastic protein present in connective tissue. As a result of protease activity, elastin hydrolysis occurs, and during this process, elastin-derived peptides (EDPs) are released.
Konrad A. Szychowski, Bartosz Skóra, Jakub Tobiasz, Jan Gmiński   +3 more
doaj   +1 more source

Association between serum elastin-derived peptides and abdominal aortic calcification in peritoneal dialysis patients: a cross-sectional study

Renal Failure, 2021
Background Peritoneal dialysis (PD) patients experience accelerated arterial aging, which is characterized by elastin degradation. Elastin-derived peptides (EDPs) are direct products of elastin fragmentation.
Shizhu Zhao, Jingyuan Cao, Jianzhong Li, Xiaochun Yang, Peiyang Cao, Jingjing Lan, Guoyuan Lu   +6 more
doaj   +1 more source

Impairment of neutrophil reactivity to elastin peptides in COPD [PDF]

Thorax, 2013
Neutrophils play an important role in the inflammatory process associated with chronic obstructive pulmonary disease (COPD). Lung-infiltrating neutrophils secrete elastinolytic proteases that participate in elastin breakdown and the formation of elastin peptides (EPs).We hypothesized that circulating neutrophil-associated immune response may be ...
Dupont, A., Dury, S., Gafa, V., Lebargy, F., Deslée, G., Guenounou, M., Antonicelli, F., Naour R, Le   +7 more
openaire   +2 more sources

Hydrogels from the Assembly of SAA/Elastin-Inspired Peptides Reveal Non-Canonical Nanotopologies

Molecules, 2022
Peptide-based hydrogels are of great interest in the biomedical field according to their biocompatibility, simple structure and tunable properties via sequence modification.
Alessandra Scelsi, Brigida Bochicchio, Andrew M. Smith, Antonio Laezza, Alberto Saiani, Antonietta Pepe   +5 more
doaj   +1 more source

Lipid Indices, Elastin Turnover and the Development of Microvascular Complications – A Study in Diabetic Patients with Arterial Hypertension

Acta Medica Bulgarica, 2019
Background and Aims: An important factor in the development of vascular wall lesions is the degradation of the elastic fiber major protein – elastin. Elastin peptides (EDP) derived from this degradation are present in the circulation and are a stimulus ...
Nikolov A., Blazhev A., Tzekova M., Kostov K., Popovski N.   +4 more
doaj   +1 more source

Preparation and Property Analyses of Elastin Peptides from Different Freshwater Fish Sources

Shipin gongye ke-ji
In order to fully utilize freshwater fish resources and develop new sources of elastin peptides, the basic information of the whole heart and bulbus arteriosus of three common bulk freshwater fish was measured in this study, including their mass, total ...
Shunfeng TIAN, Jing SHI, Shuping MA, Mengmeng FENG, Yongkang LUO, Yanfei JIANG, Chunyue ZHAO   +6 more
doaj   +1 more source

Research Progress on the Preparation of Elastin Peptides and Their Effect on Delaying Skin Aging

Shipin gongye ke-ji
Elastin, the primary structural component of elastic fibers, serves as a vital protein that imparts elasticity and tensile resilience to skin and other connective tissues.
Jing SHI, Shuping MA, Shunfeng TIAN, Yongkang LUO, Yanfei JIANG, Chunyue ZHAO   +5 more
doaj   +1 more source

Fibrous Scaffolds From Elastin-Based Materials

Frontiers in Bioengineering and Biotechnology, 2021
Current cutting-edge strategies in biomaterials science are focused on mimicking the design of natural systems which, over millions of years, have evolved to exhibit extraordinary properties. Based on this premise, one of the most challenging tasks is to
Jose Carlos Rodriguez-Cabello, Jose Carlos Rodriguez-Cabello, Israel Gonzalez De Torre, Israel Gonzalez De Torre, Miguel González-Pérez, Miguel González-Pérez, Fernando González-Pérez, Fernando González-Pérez, Irene Montequi, Irene Montequi   +9 more
doaj   +1 more source