Results 11 to 20 of about 13,438 (200)

Fingerprinting Desmosine-Containing Elastin Peptides [PDF]

Journal of the American Society for Mass Spectrometry, 2015
Elastin is a vital protein of the extracellular matrix of jawed vertebrates and provides elasticity to numerous tissues. It is secreted in the form of its soluble precursor tropoelastin, which is subsequently cross-linked in the course of the elastic fiber assembly.
Schräder, Christoph U, Heinz, Andrea, Majovsky, Petra, Schmelzer, Christian E H   +3 more
openaire   +3 more sources

Recent Advances in Elastin-Based Biomaterial

Journal of Pharmacy & Pharmaceutical Sciences, 2020
Elastin is one of the main components of the extracellular matrix; it provides resistance and elasticity to a variety of tissues and organs of the human body, besides participating in cellular signaling.
María Luisa Del Prado Audelo, Néstor Mendoza-Muñoz, Lidia Escutia-Guadarrama, David Giraldo-Gomez, Maykel González-Torres, Benjamín Florán, Hernán Cortés, Gerardo Leyva-Gomez   +7 more
doaj   +1 more source

The Elastin Receptor Complex: An Emerging Therapeutic Target Against Age-Related Vascular Diseases

Frontiers in Endocrinology, 2022
The incidence of cardiovascular diseases is increasing worldwide with the growing aging of the population. Biological aging has major influence on the vascular tree and is associated with critical changes in the morphology and function of the arterial ...
Dignê Tembely, Aubéri Henry, Laetitia Vanalderwiert, Kevin Toussaint, Amar Bennasroune, Sébastien Blaise, Hervé Sartelet, Stéphane Jaisson, Céline Galés, Laurent Martiny, Laurent Duca, Béatrice Romier-Crouzet, Pascal Maurice   +12 more
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Targeted delivery of pentagalloyl glucose inhibits matrix metalloproteinase activity and preserves elastin in emphysematous lungs

Respiratory Research, 2021
Background Elastin degradation has been established as one of the driving factors of emphysema. Elastin-derived peptides (EDPs) are shown to act as a chemoattractant for monocytes.
Vaideesh Parasaram, Xiaoying Wang, Pantrika Krisanarungson, Narendra Vyavahare   +3 more
doaj   +1 more source

Interaction between the Elastin Peptide VGVAPG and Human Elastin Binding Protein [PDF]

Journal of Biological Chemistry, 2013
The elastin binding protein (EBP), a spliced variant of lysosomal β-galactosidase, is the primary receptor of elastin peptides that have been linked to emphysema, aneurysm and cancer progression. The sequences recognized by EBP share the XGXXPG consensus pattern found in numerous matrix proteins, notably in elastin where the VGVAPG motif is repeated ...
Blanchevoye, Charlotte, Floquet, Nicolas, Scandolera, Amandine, Baud, Stéphanie, Maurice, Pascal, Bocquet, Olivier, Blaise, Sébastien, Ghoneim, Christelle, Cantarelli, Benoît, Delacoux, Frédéric, Dauchez, Manuel, Efremov, Roman G, Martiny, Laurent, Duca, Laurent, Debelle, Laurent   +14 more
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In-situ formed elastin-based hydrogels enhance wound healing via promoting innate immune cells recruitment and angiogenesis

Materials Today Bio, 2022
Harnessing the inflammation and angiogenesis is extremely important in wound healing. In this study, we developed bioactive elastin-based hydrogels which can recruit and modulate the innate immune cells and accelerate angiogenesis in the wound site and ...
Duo-Mei Tian, Huan-Huan Wan, Jia-Reng Chen, Yong-Bin Ye, Yong He, Yu Liu, Lu-Yao Tang, Zhong-Yuan He, Kai-Zheng Liu, Chong-Jian Gao, Sheng-Lin Li, Qian Xu, Zheng Yang, Chen Lai, Xiao-Jun Xu, Chang-Shun Ruan, Yun-Sheng Xu, Chao Zhang, Liang Luo, Le-Ping Yan   +19 more
doaj   +1 more source

Engineering Natural and Recombinant Silks for Sustainable Biodevices

Frontiers in Chemistry, 2022
Silk fibroin (SF) is a structural protein derived from natural silkworm silks. Materials fabricated based on SF usually inherit extraordinary physical and biological properties, including high mechanical strength, toughness, optical transparency ...
Xinchen Shen, Haoyuan Shi, Hongda Wei, Boxuan Wu, Qingyuan Xia, Jingjie Yeo, Wenwen Huang, Wenwen Huang   +7 more
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The liquid structure of elastin

eLife, 2017
The protein elastin imparts extensibility, elastic recoil, and resilience to tissues including arterial walls, skin, lung alveoli, and the uterus. Elastin and elastin-like peptides are hydrophobic, disordered, and undergo liquid-liquid phase separation ...
Sarah Rauscher, Régis Pomès
doaj   +1 more source

Characterization of novel interactions with membrane NEU1 highlights new regulatory functions for the Elastin Receptor Complex in monocyte interaction with endothelial cells

Cell & Bioscience, 2021
Background Vascular aging is associated with remodeling of elastin, one of the main extracellular matrix component of the arterial wall, and production of elastin-derived peptides (EDP).
Olivier Bocquet, Dignê Tembely, Damien Rioult, Christine Terryn, Béatrice Romier, Amar Bennasroune, Sébastien Blaise, Hervé Sartelet, Laurent Martiny, Laurent Duca, Pascal Maurice   +10 more
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Exploring the Therapeutic Potential of Elastase Inhibition in Age-Related Macular Degeneration in Mouse and Human

Cells, 2023
Abnormal turnover of the extracellular matrix (ECM) protein elastin has been linked to AMD pathology. Elastin is a critical component of Bruch’s membrane (BrM), an ECM layer that separates the retinal pigment epithelium (RPE) from the underlying ...
Soumya Navneet, Carlene Brandon, Kit Simpson, Bärbel Rohrer   +3 more
doaj   +1 more source