Results 161 to 170 of about 76,474 (248)

Male genital lichen sclerosus

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
Male genital lichen sclerosus is driven by chronic, occluded exposure of susceptible genital epithelium to urine, rather than infection or autoimmunity. This review synthesizes clinical, anatomical and molecular evidence showing how microincontinence and occlusion initiate inflammation, fibrosis and carcinogenesis, and explains the curative effect of ...
Georgios Kravvas   +3 more
wiley   +1 more source

Tropoelastin and Elastin Assembly

open access: yes
Elastic fibers are an important component of the extracellular matrix, providing stretch, resilience and cell interactivity to a broad range of elastic tissues. Elastin makes up the majority of elastic fibers and is formed by the hierarchical assembly of
Weiss, Anthony S   +5 more
core   +2 more sources

Female genital lichen sclerosus

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
This review provides a comprehensive overview of clinical presentation and emerging evidence supporting a predominantly immune‐mediated pathogenesis characterized by Th1‐skewed inflammation, epithelial dysfunction and progressive fibrosis. Contributory factors including the emerging role for occlusive exposure of susceptible epithelium to urine are ...
Ashley Spencer, Sandra Jerkovic Gulin
wiley   +1 more source

Molecular MRI monitoring of cyclodextrin therapy in murine abdominal aortic aneurysms. [PDF]

open access: yesSci Rep
Heyl JL   +14 more
europepmc   +1 more source

Cyclin‐dependent kinase 13 is indispensable for normal mouse heart development

open access: yesJournal of Anatomy, Volume 246, Issue 4, Page 616-630, April 2025.
Congenital heart disease (CHD) is the most common defect in live births. The role of cyclin‐dependent kinase (CDK13) in cardiogenesis and CHD was studied using a transgenic mouse model (Cdk13tm1b) carrying deletion of exons 3 and 4, causing loss of function.
Qazi Waheed‐Ullah   +8 more
wiley   +1 more source

Soft Tissue Substitutes: Current Biomaterials and Indications at Teeth and Implant Sites

open access: yesJournal of Periodontal Research, EarlyView.
This manuscript provides an updated overview of the current evidence on soft tissue graft substitutes for teeth and dental implants. When appropriately indicated, these biomaterials offer a reliable, less invasive alternative to autogenous grafts, effectively improving root coverage, keratinized mucosa width, and soft tissue thickness with reduced ...
Lorenzo Tavelli   +4 more
wiley   +1 more source

Experimental Investigation into Bipolar Sealability of Elastin-Rich Tissue. [PDF]

open access: yesMed Sci (Basel)
Kirschbaum A   +3 more
europepmc   +1 more source

Soft‐Tissue Integration of Dental Implants: Formation, Maintenance, and Relevance for Peri‐Implant Health

open access: yesJournal of Periodontal Research, EarlyView.
Sixty years after the introduction of dental implants, it is clear that soft‐tissue integration is as essential as osseointegration. This review outlines how peri‐implant soft tissues develop, protect, and sometimes fail, revealing key knowledge gaps and new opportunities to improve long‐term implant stability.
Fabiana Aellos   +6 more
wiley   +1 more source

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