Results 181 to 190 of about 76,474 (248)

Understanding exosomes in facial esthetics and skin aging

Periodontology 2000, EarlyView.
Abstract Background Skin aging is a multifactorial process mediated by intrinsic (genetic and metabolic) and extrinsic (environmental) factors leading to functional and structural deterioration, including wrinkles, loss of collagen and elastin, as well as various pigmentation disorders.
Richard J. Miron, Catherine Davies, Anton Sculean, Paras Ahmad   +3 more
wiley   +1 more source

Antielastase and Antihyaluronidase Activity of Isomangiferin, a Xanthone with Strong Antioxidant Properties. [PDF]

Int J Mol Sci
Hering A, Szafrański K, Mikolaszek B, Milewska K, Kucher M, Komala A, Kowalewska A, Stefanowicz-Hajduk J.   +7 more
europepmc   +1 more source

Understanding extracellular vesicles in antiaging

Periodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad, Nathan E. Estrin, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source

Impact of aging on neck vasculature and brain biochemistry in female mice. [PDF]

Physiol Rep
Jones AR, Jarrahi A, Karpowich K, Moody E, Renner L, Brown LP, Tressler CM, Crouch AC.   +7 more
europepmc   +1 more source

Impaired Windkessel function and proximal aortic stiffness: Linking vascular ageing to cognitive decline

Experimental Physiology, EarlyView.
Abstract Central arterial stiffening, particularly of the proximal aorta, is increasingly recognised as a pivotal contributor to cardiovascular disease, dementia, and mild cognitive impairment. Loss of Windkessel function amplifies pulsatile pressure, reduces diastolic perfusion and accelerates microvascular damage in the brain.
Jun Sugawara, Hirofumi Tanaka
wiley   +1 more source

Subclinical Venous Injury in Transvenous Lead Extraction: Histological Correlation With Clinical Risk Factors. [PDF]

J Cardiovasc Electrophysiol
Lateef AU, Vardar U, Hochwald A, Nassar A, Ladas T, Chiriac A, Niekerk CV, Kusumoto F, Kella DK.   +8 more
europepmc   +1 more source

Tissue Structure as a Primary Factor Influencing Vascular Sealing: Results of an Ex Vivo Study on Porcine Carotid Arteries. [PDF]

Bioengineering (Basel)
Kirschbaum A, Raico D, Kirschbaum F, Jesinghaus M, Mirow N.   +4 more
europepmc   +1 more source

Contributions of vascular ageing to late‐onset Alzheimer's disease

Experimental Physiology, EarlyView.
Abstract Late‐onset Alzheimer's disease (LOAD) is an age‐related disease that is strongly associated with vascular risk factors and cerebrovascular impairments. As such, changes in the vasculature with advancing age likely contribute to LOAD, but the mechanisms underlying these contributions remain incompletely understood.
Skylyn J. Ferguson, Young Deanna Choi, Ashley E. Walker   +2 more
wiley   +1 more source

Bulk density-calibrated fiber networks reveal local weakness as the driver of protease-dependent aortic failure. [PDF]

Int J Eng Sci
Gueldner PH, Agrawal Y, Rajagopal KR, Vorp DA, Maiti S.   +4 more
europepmc   +1 more source

Lower cerebral blood flow but not cerebrovascular response in elastin haploinsufficient mice

Experimental Physiology, EarlyView.
Abstract Elastin insufficiency is associated with structural differences in the large elastic arteries and cerebral artery dysfunction. However, previous studies have not assessed potential sex differences in cerebrovascular function. We measured cerebral blood flow (CBF) using arterial spin labeling MRI at rest and in response to hypercapnia challenge
Abigail E. Cullen, Emily H. Reeve, Nick R. Winder, Grant D. Henson, Nayantara Arora, Thomas Leonhardt, Ainsley Hogan, Sahana Krishna Kumaran, Naly Setthavonsack, Victoria Krajbich, Art Riddle, Benjamin Zimmerman, Nabil J. Alkayed, Martin M. Pike, Randall L. Woltjer, Ashley E. Walker   +15 more
wiley   +1 more source