Results 201 to 210 of about 76,474 (248)

Vascular smooth muscle cell mechanotransduction: Pathways, phenotypes and emerging technologies

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Vascular smooth muscle cells are exposed to mechanical stimuli from the blood flow and the extracellular matrix. The cells sense the signals from cyclic stretch, shear stress, hydrostatic pressure and matrix stiffness through specialized mechanosensors, such as mechanosensitive ion channels or cell surface receptors including ...
Nivethitha Kota Lakshminaraasimulu   +3 more
wiley   +1 more source

Caloric restriction and aerobic exercise differentially counteract muscle–tendon dysfunction following diet‐induced obesity in C57BL/6J mice

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Diet‐induced obesity induced fibro‐adipogenic remodelling of the muscle–tendon unit, characterized by increased fibrosis, reduced specific force, impaired relaxation kinetics, elevated hysteresis, and reduced aerobic capacity and glucose tolerance.
Leonardo Cesanelli   +9 more
wiley   +1 more source

Biofidelic Simulations of the Ross Procedure: Arterial Growth and Remodeling in an Anatomical Context. [PDF]

open access: yesInt J Numer Method Biomed Eng
Audenay M   +7 more
europepmc   +1 more source

Avian Eggshell Evolutionary Adaptations Inform Biomimetic Strategies for Next‑Generation Precision Cancer Theranostics

open access: yesAdvanced Oncology, Volume 1, Issue 1, December 2026.
ABSTRACT The avian eggshell is a sophisticated, multi‐functional biocomposite and, more importantly, an autonomous life‐support system evolved to safeguard embryonic development across dynamic and hostile environments. Discussing eggshell‐inspired biomaterials beyond simple structural imitation, this review translates these evolutionary survival ...
Zhiqiang Liu   +11 more
wiley   +1 more source

Autologous cutis and subcutis micrografts combined with a collagen-elastin dermal scaffold for chronic wounds: a retrospective single-arm clinical study with prospectively collected data. [PDF]

open access: yesFront Pharmacol
Ioannidis O   +13 more
europepmc   +1 more source

Radiation‐Induced Skin Injury in Cancer Radiotherapy: From Mechanisms to Management

open access: yesAdvanced Oncology, Volume 1, Issue 1, December 2026.
Radiation‐induced skin injuries (RISI) remain a significant challenge faced by cancer patients receiving radiotherapy (RT). This perspective article examines the pathophysiology of RISI and evaluates the currently existing and emerging therapeutic strategies, including stem cell‐derived exosomes and advanced hydrogels.
Zeynep Meral Toutoungi   +3 more
wiley   +1 more source

Elastin calcification during the initial stage of vascular calcification in kl/kl mice is suppressed by the calcimimetic upacicalcet. [PDF]

open access: yesSci Rep
Hasegawa T   +7 more
europepmc   +1 more source

Dermal fibroblasts cultured from aged human skin display a pro‐inflammatory phenotype

open access: yesJournal of Cell Communication and Signaling, Volume 20, Issue 4, December 2026.
Cell‐Autonomous and Microenvironment‐Driven Changes in Human Skin Dermal Fibroblasts During Aging. Aging induces a cell‐autonomous pro‐inflammatory fibroblast phenotype (independent of the ECM microenvironment), with upregulation of 300 genes primarily associated with cytokine and chemokine pathways (e.g., TNF) and downregulation of 177 genes involved ...
Yilei Cui   +6 more
wiley   +1 more source

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