Results 211 to 220 of about 101,796 (243)
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The substructure of elastin

Experimental and Molecular Pathology, 1978
Abstract Samples of purified elastins from nuchal ligaments and aortas of bovines aged 6 days, 15 months, and 10 years have been used to study elastin ultrastructure. Oxalic acid-solubilized elastin samples (α-elastins) have been fractionated by gel chromatography and caused to undergo reversible phase separation (coacervation) by heating and by ...
W.J. Cliff   +3 more
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Structure of Elastin

2021
As the extracellular matrix protein, elastin is a crucial component of connective tissue in life. It is responsible for the structural integrity and function of tissues undergoing reversible extensibility or deformability, even though it may make up only a small percentage of a tissue.
Shengjie Ling, Yuelong Xiao, Ying Pei
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Elastin

2005
Elastin is a key extracellular matrix protein that is critical to the elasticity and resilience of many vertebrate tissues including large arteries, lung, ligament, tendon, skin, and elastic cartilage. Tropoelastin associates with multiple tropoelastin molecules during the major phase of elastogenesis through coacervation, where this process is ...
Suzanne M, Mithieux, Anthony S, Weiss
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The hydroxyproline of elastin

Biochimica et Biophysica Acta (BBA) - Protein Structure, 1969
Abstract The question of whether the hydroxyproline found in elastin represents contamination with collagen was studied by subjecting solubilized elastin (α- plus β-elastin) to prolonged collagenase digestion. No loss of hydroxyproline was seen, and it is concluded that hydroxyproline is indeed a constituent of elastin in which it occurs in a ...
J. Peter Bentley, Albert N. Hanson
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Radioemmunoassay of Elastin

Connective Tissue Research, 1977
Highly purified elastin was prepared from bovine ligamentum nuchae by hot alkali extraction. Antisera to the protein, developed against suspensions or acid solubilized preparations, were obtained from rabbits and guinea pigs. Of a large number of proteins, only insoluble elastin (from the aortae of several animal species) and tropoelastin, the putative
LaBella F, Houle D
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Elastin and Elastin-Based Polymers

2009
Tropoelastin, elastin and elastin-derived peptides are very interesting molecules for the production of nanodevices with different purposes. Because of its peculiar structure and physical chemical characteristics, due to alternate hydrophobic and hydrophilic domains, tropoelastin can be fragmented and each fragment used for specific functions, such as ...
QUAGLINO, Daniela   +2 more
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A microassay for elastin

Analytical Biochemistry, 1973
Abstract An assay for insoluble elastin is described. The procedure involves isolation of elastin by 5 m guanidine and autoclaving. The residue is solubilized with elastase and the protein released estimated colorimetrically. This assay method is sensitive in the range: 50–300 μg.
Yvonne Naum   +3 more
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Elastin in asthma

Pulmonary Pharmacology & Therapeutics, 2012
Extracellular matrix is generally increased in asthma, causing thickening of the airways which may either increase or decrease airway responsiveness, depending on the mechanical requirements of the deposited matrix. However, in vitro studies have shown that the altered extracellular matrix produced by asthmatic airway smooth muscle cells is able to ...
Janette K. Burgess   +2 more
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The Acidophilia of Elastin

Stain Technology, 1963
Conditions relevant to the acceptance of acid dyes by the elastin of the aorta are as follows: (a) Fixation. Cold alcohol is poor, formol-sublimate, hest; others are intermediate. (h) Acid dyes used. Bromphenol blue is best, light green is poor, acid fuchsin is unstable in alkaline solution.
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Reconstitution of Elastin

Nature, 1967
PARTRIDGE et al.1 observed that hydrolysis of pure insoluble elastin from bovine ligamentum nuchae by oxalic acid gave rise to soluble elastin consisting of two fractions: α-elastin with a mean molecular weight of 60,000–84,000; and β-elastin with a mean molecular weight of 5,000.
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