Results 81 to 90 of about 113,337 (338)

Dissolving Microneedle for Maintaining the Integrity of HPV Virus‐Like Particles Enabling Durable Sterile Protection Across Various Mucosal Tissues

open access: yesAdvanced Healthcare Materials, EarlyView.
A novel dissolving microneedle platform preserves HPV virus‐like particle (VLP) immunogenicity by maintaining structural integrity, crucial for eliciting potent immune responses. Buccal administration induces robust immune response, high neutralizing antibody titers, and durable sterile protection across oral and vaginal mucosal sites.
Hyemi Kim   +12 more
wiley   +1 more source

In-situ formed elastin-based hydrogels enhance wound healing via promoting innate immune cells recruitment and angiogenesis

open access: yesMaterials Today Bio, 2022
Harnessing the inflammation and angiogenesis is extremely important in wound healing. In this study, we developed bioactive elastin-based hydrogels which can recruit and modulate the innate immune cells and accelerate angiogenesis in the wound site and ...
Duo-Mei Tian   +19 more
doaj  

Control of Elastin Synthesis

open access: yesJournal of Investigative Dermatology, 1982
mRNA was isolated from the thoracic aortas of 16-day chick embryos and used to synthesize blunt-ended heteroduplex molecules consisting of one strand of mRNA and one of cDNA using AMV reverse transcriptase and S1 nuclease. The duplexes were tailed with dCTP and hybridized to the plasmid pBR322 which had been restricted with Pst I and tailed with dGTP ...
William Burnett   +3 more
openaire   +3 more sources

The Impact of Vein Mechanical Compliance on Arteriovenous Fistula Outcomes [PDF]

open access: yes, 2016
© 2016 Elsevier Inc. Background Arteriovenous fistulae (AVFs) are the preferred access for hemodialysis but suffer a high early failure rate. The aim of this study was to determine how venous distensibility, as measured in vitro, relates to early ...
Barnes, Rachel   +4 more
core   +1 more source

Nanocarrier‐Based Targeting of Pattern Recognition Receptors as an Innovative Strategy for Enhancing Sepsis Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
This review highlights recent progress in nanocarriers targeting pattern recognition receptors (PRRs), including Toll‐like and NOD‐like receptors, for enhancing the treatment of bacterial sepsis and related complications. These nanomedicines deliver antibiotics and anti‐inflammatory agents while modulating immune responses.
Eman A. Ismail   +3 more
wiley   +1 more source

Adipocytes, aldosterone and obesity-related hypertension [PDF]

open access: yes, 2016
Understanding the mechanisms linking obesity with hypertension is important in the current obesity epidemic as it may improve therapeutic interventions.
Friederich-Persson, Malou   +3 more
core   +1 more source

Biphasic Granular Bioinks for Biofabrication of High Cell Density Constructs for Dermal Regeneration

open access: yesAdvanced Healthcare Materials, EarlyView.
This study introduces a biphasic granular bioink (µInk) that enables 3D bioprinting of high cell density constructs for dermal regeneration. The bioink promotes cell proliferation, ECM deposition, and neovascularization, leading to tissue integration and reduced scar formation in vivo.
Rozalin Shamasha   +16 more
wiley   +1 more source

Automated evaluation of probe-based confocal laser endomicroscopy in the lung.

open access: yesPLoS ONE, 2020
RATIONALE:Probe-based confocal endomicroscopy provides real time videos of autoflourescent elastin structures within the alveoli. With it, multiple changes in the elastin structure due to different diffuse parenchymal lung diseases have previously been ...
David Bondesson   +5 more
doaj   +1 more source

Immunohistochemical Study of Smooth Muscle Cells and Elastin in Goose Lungs

open access: yesFolia Veterinaria, 2022
There are many differences (morphological, physiological and mechanical) between the lungs of birds and the lungs of mammals. Birds have a more efficient exchange of oxygen and carbon dioxide than mammals. In this article, we studied the presence of four
Marettová E., Maretta M.
doaj   +1 more source

A structural approach including the behavior of collagen cross-links to model patient-specific human carotid arteries [PDF]

open access: yes, 2014
The final publication is available at Springer via http://dx.doi.org/10.1007/s10439-014-0995-7The objective of this work is to develop a remodeling model for biological matter coupling two different processes in a 3D framework: reorientation of the ...
Martínez, Miguel Angel   +2 more
core   +2 more sources

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