Results 61 to 70 of about 112,379 (307)

Amyloidogenic Peptide Fragments Designed From Bacterial Collagen‐like Proteins Form Hydrogel

Advanced Functional Materials, EarlyView.
This study identified amyloidogenic sequence motifs in bacterial collagen‐like proteins and exploited these to design peptides that self‐assemble into β‐sheet fibers and form hydrogels. One hydrogel supported healthy fibroblast growth, showing promise for biocompatible materials. Our work demonstrates that bacterial sequences can be harnessed to create
Vamika Sagar, Xuen J Ng, Lukas Lechel, Ashish Chand Rajwar, Hendrik Bargel, Abhishek A. Jalan   +5 more
wiley   +1 more source

Applications of Elastin in Cosmetics: Prospects and Challenges

Cosmetics
Elastin is a crucial component of the extracellular matrix that plays a significant role in maintaining skin elasticity and firmness. Within the dermis, elastin works in collaboration with collagen to form supportive structures that contribute to the ...
Ting Lei, Lin Ye, Yunlin Pei, Huaiqing Sun, Chaowan Guo   +4 more
doaj   +1 more source

Plasma Soluble Human Elastin Fragments as an Intra-Aneurysmal Localized Biomarker for Ruptured Intracranial Aneurysm [PDF]

, 2018
Background—Fragmentation of the tunica media is a hallmark of intracranial aneurysm formation, often leading to aneurysmal progression and subsequent rupture.
Allan, Lauren, Hasan, David M., Hudson, Joseph, Ishii, Daizo, Jabbour, Pascal, Nakagawa, Daichi, Ortega-Gutierrez, Santiago, Samaniego, Edgar A., Teferi, Nahom, Zanaty, Mario   +9 more
core   +1 more source

2H and 13C NMR studies on the temperature-dependent water and protein dynamics in hydrated elastin, myoglobin and collagen

, 2009
2H NMR spin-lattice relaxation and line-shape analyses are performed to study the temperature-dependent dynamics of water in the hydration shells of myoglobin, elastin, and ...
Herbers, C. R., Lusceac, S. A., Vogel, M.   +2 more
core   +1 more source

Elastin is Localised to the Interfascicular Matrix of Energy Storing Tendons and Becomes Increasingly Disorganised With Ageing [PDF]

, 2017
Tendon is composed of fascicles bound together by the interfascicular matrix (IFM). Energy storing tendons are more elastic and extensible than positional tendons; behaviour provided by specialisation of the IFM to enable repeated interfascicular sliding
A Heinz, AJ Viera, B Vrhovski, C Thorpe, C Thorpe, CT Thorpe, CT Thorpe, CT Thorpe, CT Thorpe, CT Thorpe, CT Thorpe, D Bedell-Hogan, EL Batson, F Ramirez, H Birch, H Oxlund, H Tempfer, HL Birch, IM Braverman, J Fallon, JA Foster, JA Foster, JA Pierce, JE Wagenseil, JF Innes, K Kubo, KD Smith, L Nimeskern, L Robert, L Robert, M Akagawa, M Benjamin, M Luisetti, MJ Sherratt, P Berens, P Kannus, PPY Lui, R Alexander, R Ker, SA Fenwick, SE Greenwald, SG Dakin, T Watanabe, TB Csóka, TC Lee, TM Grant, TM Grant, Z Gunja-Smith, Z Liu   +48 more
core   +4 more sources

The Terminal Domains of Collagen‐Like Silk Direct Molecular Interactions and Liquid–Liquid Phase Separation‐Mediated Material Assembly

Advanced Functional Materials, EarlyView.
Terminal domains of recombinant collagen‐like silk regulate hierarchical self‐assembly across molecular and material scales. We show that terminal domains of collagen‐like silk enhance triple‐helix stability and drive liquid–liquid phase separation, enabling reversible formation of fibers and self‐healing films.
Mengjie Shen, Daniil Astapov, Nur Alia Oktaviani, Mami Goto, Keiji Numata, A. Sesilja Aranko   +5 more
wiley   +1 more source

2.8 Unique patterns of elastin degradation in ascending aortic aneurysms in bicuspid aortic valve patients

Artery Research, 2020
Background: Bicuspid aortic valve patients (BAV) are associated with increased risk of ascending aortic aneurysms. However, is unclear whether matrix degradation varies in different ascending aneurysm aetiologies.
Ya Hua Chim, Hannah Davies, Omar Nawaytou, Mark Field, Jillian Madine, Riaz Akhtar   +5 more
doaj   +1 more source

Degradation of connective tissue matrices by macrophages. III. Morphological and biochemical studies on extracellular, pericellular, and intracellular events in matrix proteolysis by macrophages in culture. [PDF]

, 1980
We have shown that macrophages in culture degrade the glycoproteins and amorphous elastin of insoluble extracellular matrices. Ultrastructural observation of the macrophage-matrix interaction revealed that connective tissue macromolecules were ...
Bainton, DF, Jones, PA, Werb, Z
core  

A double safety lock tumor-specific device for suicide gene therapy in breast cancer [PDF]

, 2020
Producción CientíficaThe complexity and continuous evolution of cancer make the design of novel strategies of treatment a constant challenge in biomedicine.
Arias Vallejo, Francisco Javier, Girotti, Alessandra, Muñoz Martínez, Raquel, Piña Lancho, María Jesús, Rodríguez Cabello, José Carlos, Serrano, Sofía   +5 more
core   +2 more sources

A Novel Decellularized Fibrocartilage Graft Promotes Tympanic Membrane Repair

Advanced Healthcare Materials, EarlyView.
An off‐the‐shelf decellularized porcine meniscus fibrocartilage graft (MEND) is engineered for pediatric tympanoplasty. Featuring a microchannel architecture that promotes host cell invasion, MEND rapidly closes tympanic membrane perforations and fully remodels in vivo, outperforming fascia and matching cartilage grafts while avoiding donor‐site ...
Paul M. Gehret, Ryan M. Friedman, Gautham Nair, Stephanie L. Fung, Dana D. Ragbirsingh, John Germiller, Riccardo Gottardi   +6 more
wiley   +1 more source