Results 61 to 70 of about 69,247 (300)

Is newly-secreted elastin cleaved to a smaller molecule before being incorporated into crosslinked elastin fibers?

, 1977
The biosynthesis of elastin was examined in matrix-free cells isolated by enzymatic digestion of aortas from 17 day old chick embryos. When the cells were incubated with (14C) proline and then were rapidly boiled in buffer containing high concentrations ...
BRESSAN, GIORGIO, Prockop DJ
core   +1 more source

Integrated Single‐Cell and Spatial Analysis Reveals a Metabolic‐Immune Axis Driving Aortic Dissection

Advanced Science, EarlyView.
Single‐cell and spatial profiling of 110 human thoracic aortic samples reveals a stromal–immune circuit driving aortic dissection. An elastin‐rich fibroblast subset is depleted with age and markedly reduced in disease, weakening aortic wall integrity.
Jing Tao, Huanjie Yang, Jiahui Yong, Xueting Chen, Qiang Zhao, Xueli Wu, Lei Yan, Li Pang, Fan Luo, Mengjun Yu, Shanshan Pan, Deyang Li, Rouxi Chen, Juan Wang, Zhensheng Dong, Fan Yang, Yue Wang, Yang Chen, Hongjian Zheng, Zhimin Yang, Zijie Wang, Karsten Kristiansen, Hui Peng, Xiaodong Fang, Juan Shen, Yining Yang   +25 more
wiley   +1 more source

Acquired Localized Cutis Laxa due to Increased Elastin Turnover

Case Reports in Dermatology, 2016
Cutis laxa is a rare disease characterized by abnormal skin wrinkling and laxity, due to decreased elastin synthesis or structural extracellular matrix defects.
Rie Harboe Nygaard, Scott Maynard, Peter Schjerling, Michael Kjaer, Klaus Qvortrup, Vilhelm A. Bohr, Lene J. Rasmussen, Gregor B.E. Jemec, Michael Heidenheim   +8 more
doaj   +1 more source

Multiresponsive Nanoscale Self-Assembly of Azurin-Elastin-like Polypeptide Fusion Protein for Enhanced Prostate Cancer Therapy

, 2023
A fusion protein composed of a bacterial protein, azurin, having antineoplastic properties and a thermally responsive structural cationic elastin-like protein (ELP), is designed, cloned, expressed, and purified.
Ritu Bhardwaj (603196), Prashant Mishra (742994)   +1 more
core   +1 more source

Enhancing Blood Circulation With Epsilon‐Near‐Zero (ENZ) Materials via the Far‐Infrared Window of Human Skin

Advanced Science, EarlyView.
Epsilon‐near‐zero (ENZ) silicon carbide enables a selective far‐infrared emitter spectrally aligned with the human skin window around 10 µm for wavelength‐matched thermal therapy. In 25 within‐subject trials (50 hands) monitored by laser speckle contrast imaging, SiC increases blood perfusion by 30.2% versus a broadband graphite emitter while ...
Wen‐Teng Yao, Shan‐Chiao Yang, Ming‐Feng Tsai, Hsuen‐Li Chen   +3 more
wiley   +1 more source

OPTIMUM METHOD FOR COMMON CARP ELASTIN EXTRACTION AND THE ANTI-OXIDANT ACTIVITY OF ELASTIN ENZYMATIC HYDROLYSATE

The Iraqi Journal of Agricultural science
This study aimed to compare five protocols to optimize elastin purification, where purification protocols for elastin generally result in greatly damaged elastin fibres and this likely influences the biological response. The optimal protocol for elastin
A. M. Kadhim A. M. Kadhim, K. A. Shakir K. A. Shakir   +1 more
doaj   +1 more source

Generation of Self‐Organizing Macrovascular Constructs by Bioprinting Human iPSC‐Derived Mesodermal Progenitor Cells

Advanced Science, EarlyView.
ABSTRACT Vascularization remains a major obstacle in tissue engineering. Here, we introduce a bioprinting strategy to generate centimeter‐scale, self‐organizing “mother vessel” constructs from iPSC‐derived hiMPCs. By optimizing bioink composition, printing was accomplished in a single‐step approach. Within one week, hiMPCs differentiated into both CD31+
Leyla E. Dogan, Nathaly A. Chicaiza‐Cabezas, Florian Kleefeldt, Philipp Wörsdörfer, Jürgen Groll, Süleyman Ergün   +5 more
wiley   +1 more source

Elastin hydrogels

, 2023
This bachelor thesis is focused on elastin hydrogels for medical application. The aim of the experimental part was using elastin as an additional substance in polysaccharide gel matrices.
Burianová, Veronika
core   +1 more source

Influence of aging on dermal elastin fiber architecture and skin firmness assessed by finite element modeling

Scientific Reports
Skin firmness and elasticity are largely determined by the dermal extracellular matrix, particularly the elastin fiber network. Age-related degradation of elastin alters its architecture, contributing to diminished skin resilience.
Fei Jiang, Takeshi Tohgasaki, Mayuko Kami, Ryota Sanuki, Yuya Nakata, Shinya Kondo, Xian Chen   +6 more
doaj   +1 more source

i‐Tac: Inverse Design of 3D‐Printed Tactile Elastomers with Tuneable Optical and Mechanical Properties

Advanced Intelligent Systems, EarlyView.
Inspired by the multi‐tissue architecture of the human fingertip dermis (A), this work introduces a mixture design using three PolyJet materials (AC/TM/GM) to expand the achievable elastomer property space (B). An inverse design pipeline (i‐Tac) is developed to map target optical/mechanical requirements to optimal material compositions (C), enabling ...
Wen Fan, Dandan Zhang
wiley   +1 more source